Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 78

1.

β-Eliminative releasable linkers adapted for bioconjugation of macromolecules to phenols.

Schneider EL, Robinson L, Reid R, Ashley GW, Santi DV.

Bioconjug Chem. 2013 Dec 18;24(12):1990-7. doi: 10.1021/bc4002882. Epub 2013 Nov 20.

PMID:
24171387
2.

Predictable and tunable half-life extension of therapeutic agents by controlled chemical release from macromolecular conjugates.

Santi DV, Schneider EL, Reid R, Robinson L, Ashley GW.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6211-6. doi: 10.1073/pnas.1117147109. Epub 2012 Apr 2.

3.

Hydrogel drug delivery system with predictable and tunable drug release and degradation rates.

Ashley GW, Henise J, Reid R, Santi DV.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2318-23. doi: 10.1073/pnas.1215498110. Epub 2013 Jan 23.

4.

Macromolecular prodrug that provides the irinotecan (CPT-11) active-metabolite SN-38 with ultralong half-life, low C(max), and low glucuronide formation.

Santi DV, Schneider EL, Ashley GW.

J Med Chem. 2014 Mar 27;57(6):2303-14. doi: 10.1021/jm401644v. Epub 2014 Mar 6.

PMID:
24494988
5.

Mutual prodrugs containing bio-cleavable and drug releasable disulfide linkers.

Jain AK, Gund MG, Desai DC, Borhade N, Senthilkumar SP, Dhiman M, Mangu NK, Mali SV, Dubash NP, Halder S, Satyam A.

Bioorg Chem. 2013 Aug;49:40-8. doi: 10.1016/j.bioorg.2013.06.007. Epub 2013 Jul 3.

PMID:
23886697
6.

Undesired versus designed enzymatic cleavage of linkers for liver targeting.

Chirapu SR, Bauman JN, Eng H, Goosen TC, Strelevitz TJ, Sinha SC, Dow RL, Finn MG.

Bioorg Med Chem Lett. 2014 Feb 15;24(4):1144-7. doi: 10.1016/j.bmcl.2013.12.126. Epub 2014 Jan 8.

7.

Releasable PEGylation of proteins with customized linkers.

Filpula D, Zhao H.

Adv Drug Deliv Rev. 2008 Jan 3;60(1):29-49. Epub 2007 Aug 16. Review.

PMID:
17884239
8.

Linear and branched bicin linkers for releasable PEGylation of macromolecules: controlled release in vivo and in vitro from mono- and multi-PEGylated proteins.

Zhao H, Yang K, Martinez A, Basu A, Chintala R, Liu HC, Janjua A, Wang M, Filpula D.

Bioconjug Chem. 2006 Mar-Apr;17(2):341-51.

PMID:
16536464
9.

Elongated multiple electronic cascade and cyclization spacer systems in activatible anticancer prodrugs for enhanced drug release.

de Groot FM, Loos WJ, Koekkoek R, van Berkom LW, Busscher GF, Seelen AE, Albrecht C, de Bruijn P, Scheeren HW.

J Org Chem. 2001 Dec 28;66(26):8815-30.

PMID:
11749612
10.

Chemical adaptor systems.

Shabat D, Amir RJ, Gopin A, Pessah N, Shamis M.

Chemistry. 2004 Jun 7;10(11):2626-34. Review.

PMID:
15195294
11.

Comparison of the chemical properties of a novel amino-linker with various amino modifications.

Kojima N, Takebayashi T, Mikami A, Sugino M, Ohtsuka E, Komatsu Y.

Nucleic Acids Symp Ser (Oxf). 2008;(52):463-4. doi: 10.1093/nass/nrn235.

PMID:
18776454
12.

Structure-based design of 7-carbamate analogs of geldanamycin.

Rastelli G, Tian ZQ, Wang Z, Myles D, Liu Y.

Bioorg Med Chem Lett. 2005 Nov 15;15(22):5016-21.

PMID:
16165354
13.

Application of base cleavable safety catch linkers to solid phase library production.

Wade WS, Yang F, Sowin TJ.

J Comb Chem. 2000 May-Jun;2(3):266-75.

PMID:
10827935
14.

A carbamate-based approach to primaquine prodrugs: antimalarial activity, chemical stability and enzymatic activation.

Mata G, do Rosário VE, Iley J, Constantino L, Moreira R.

Bioorg Med Chem. 2012 Jan 15;20(2):886-92. doi: 10.1016/j.bmc.2011.11.059. Epub 2011 Dec 3.

PMID:
22189276
15.

Inhibition of carbonic anhydrases I and II by N-unsubstituted carbamate esters.

Parr JS, Khalifah RG.

J Biol Chem. 1992 Dec 15;267(35):25044-50.

16.

Reduction of the pesticides oxamyl and methomyl by FeII: effect of pH and inorganic ligands.

Strathmann TJ, Stone AT.

Environ Sci Technol. 2002 Feb 15;36(4):653-61.

PMID:
11878379
17.

Dethiobiotin synthetase: the carbonylation of 7,8-diaminonanoic acid proceeds regiospecifically via the N7-carbamate.

Gibson KJ, Lorimer GH, Rendina AR, Taylor WS, Cohen G, Gatenby AA, Payne WG, Roe DC, Lockett BA, Nudelman A, et al.

Biochemistry. 1995 Sep 5;34(35):10976-84. Erratum in: Biochemistry 1995 Dec 5;34(48):15880.

PMID:
7669755
18.

Controlled release of proteins from their poly(ethylene glycol) conjugates: drug delivery systems employing 1,6-elimination.

Greenwald RB, Yang K, Zhao H, Conover CD, Lee S, Filpula D.

Bioconjug Chem. 2003 Mar-Apr;14(2):395-403.

PMID:
12643750
19.

New detachable poly(ethylene glycol) conjugates: cysteine-cleavable lipopolymers regenerating natural phospholipid, diacyl phosphatidylethanolamine.

Zalipsky S, Qazen M, Walker JA 2nd, Mullah N, Quinn YP, Huang SK.

Bioconjug Chem. 1999 Sep-Oct;10(5):703-7.

PMID:
10502334

Supplemental Content

Support Center