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Items: 1 to 20 of 132


A derivative of chrysin suppresses two-stage skin carcinogenesis by inhibiting mitogen- and stress-activated kinase 1.

Liu H, Hwang J, Li W, Choi TW, Liu K, Huang Z, Jang JH, Thimmegowda NR, Lee KW, Ryoo IJ, Ahn JS, Bode AM, Zhou X, Yang Y, Erikson RL, Kim BY, Dong Z.

Cancer Prev Res (Phila). 2014 Jan;7(1):74-85. doi: 10.1158/1940-6207.CAPR-13-0133. Epub 2013 Oct 29.


Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation.

Kim HG, Lee KW, Cho YY, Kang NJ, Oh SM, Bode AM, Dong Z.

Cancer Res. 2008 Apr 1;68(7):2538-47. doi: 10.1158/0008-5472.CAN-07-6597.


Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors.

Chiou YS, Sang S, Cheng KH, Ho CT, Wang YJ, Pan MH.

Carcinogenesis. 2013 Jun;34(6):1315-22. doi: 10.1093/carcin/bgt042. Epub 2013 Feb 5.


Kaempferol targets RSK2 and MSK1 to suppress UV radiation-induced skin cancer.

Yao K, Chen H, Liu K, Langfald A, Yang G, Zhang Y, Yu DH, Kim MO, Lee MH, Li H, Bae KB, Kim HG, Ma WY, Bode AM, Dong Z, Dong Z.

Cancer Prev Res (Phila). 2014 Sep;7(9):958-967. doi: 10.1158/1940-6207.CAPR-14-0126. Epub 2014 Jul 3.


Docosahexaenoic acid inhibits UVB-induced activation of NF-κB and expression of COX-2 and NOX-4 in HR-1 hairless mouse skin by blocking MSK1 signaling.

Rahman M, Kundu JK, Shin JW, Na HK, Surh YJ.

PLoS One. 2011;6(11):e28065. doi: 10.1371/journal.pone.0028065. Epub 2011 Nov 28.


Involvement of ERKs and mitogen- and stress-activated protein kinase in UVC-induced phosphorylation of ATF2 in JB6 cells.

Zhu F, Zhang Y, Bode AM, Dong Z.

Carcinogenesis. 2004 Oct;25(10):1847-52. Epub 2004 Jun 10.


Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1.

Zhong S, Jansen C, She QB, Goto H, Inagaki M, Bode AM, Ma WY, Dong Z.

J Biol Chem. 2001 Aug 31;276(35):33213-9. Epub 2001 Jul 5.


Epigenetic regulation of transcription factor promoter regions by low-dose genistein through mitogen-activated protein kinase and mitogen-and-stress activated kinase 1 nongenomic signaling.

Yu L, Ham K, Gao X, Castro L, Yan Y, Kissling GE, Tucker CJ, Flagler N, Dong R, Archer TK, Dixon D.

Cell Commun Signal. 2016 Aug 31;14(1):18. doi: 10.1186/s12964-016-0141-2.


Activation of mitogen- and stress-activated kinase 1 is required for proliferation of breast cancer cells in response to estrogens or progestins.

Reyes D, Ballaré C, Castellano G, Soronellas D, Bagó JR, Blanco J, Beato M.

Oncogene. 2014 Mar 20;33(12):1570-80. doi: 10.1038/onc.2013.95. Epub 2013 Apr 22.


Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine.

Lee KW, Kang NJ, Heo YS, Rogozin EA, Pugliese A, Hwang MK, Bowden GT, Bode AM, Lee HJ, Dong Z.

Cancer Res. 2008 Feb 1;68(3):946-55. doi: 10.1158/0008-5472.CAN-07-3140.


Mitogen- and stress-activated protein kinases 1 and 2 are required for maximal trefoil factor 1 induction.

Khan P, Drobic B, Pérez-Cadahía B, Healy S, He S, Davie JR.

PLoS One. 2013 May 13;8(5):e63189. doi: 10.1371/journal.pone.0063189. Print 2013.


Inhibitory effect of citrus 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice.

Lai CS, Li S, Chai CY, Lo CY, Ho CT, Wang YJ, Pan MH.

Carcinogenesis. 2007 Dec;28(12):2581-8. Epub 2007 Oct 24.


Mitogen- and stress-activated protein kinase 1 MSK1 regulates glucocorticoid response element promoter activity in a glucocorticoid concentration-dependent manner.

Beck IM, Clarisse D, Bougarne N, Okret S, Haegeman G, De Bosscher K.

Eur J Pharmacol. 2013 Sep 5;715(1-3):1-9. doi: 10.1016/j.ejphar.2013.06.032. Epub 2013 Jul 4.


Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes.

Sundar IK, Chung S, Hwang JW, Lapek JD Jr, Bulger M, Friedman AE, Yao H, Davie JR, Rahman I.

PLoS One. 2012;7(2):e31378. doi: 10.1371/journal.pone.0031378. Epub 2012 Feb 1.

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