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Items: 1 to 20 of 63

1.

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses.

Hamming OJ, Terczyńska-Dyla E, Vieyres G, Dijkman R, Jørgensen SE, Akhtar H, Siupka P, Pietschmann T, Thiel V, Hartmann R.

EMBO J. 2013 Nov 27;32(23):3055-65. doi: 10.1038/emboj.2013.232. Epub 2013 Oct 29.

2.

A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages.

Bamford CGG, Aranday-Cortes E, Filipe IC, Sukumar S, Mair D, Filipe ADS, Mendoza JL, Garcia KC, Fan S, Tishkoff SA, McLauchlan J.

PLoS Pathog. 2018 Oct 11;14(10):e1007307. doi: 10.1371/journal.ppat.1007307. eCollection 2018 Oct.

3.

Interferon lambda 4 expression is suppressed by the host during viral infection.

Hong M, Schwerk J, Lim C, Kell A, Jarret A, Pangallo J, Loo YM, Liu S, Hagedorn CH, Gale M Jr, Savan R.

J Exp Med. 2016 Nov 14;213(12):2539-2552. Epub 2016 Oct 31.

4.

Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes.

Terczyńska-Dyla E, Bibert S, Duong FH, Krol I, Jørgensen S, Collinet E, Kutalik Z, Aubert V, Cerny A, Kaiser L, Malinverni R, Mangia A, Moradpour D, Müllhaupt B, Negro F, Santoro R, Semela D, Semmo N; Swiss Hepatitis C Cohort Study Group, Heim MH, Bochud PY, Hartmann R.

Nat Commun. 2014 Dec 23;5:5699. doi: 10.1038/ncomms6699. Erratum in: Nat Commun. 2015;6:7280.

PMID:
25534433
5.

HCV infection selectively impairs type I but not type III IFN signaling.

Chandra PK, Bao L, Song K, Aboulnasr FM, Baker DP, Shores N, Wimley WC, Liu S, Hagedorn CH, Fuchs SY, Wu T, Balart LA, Dash S.

Am J Pathol. 2014 Jan;184(1):214-29. doi: 10.1016/j.ajpath.2013.10.005. Epub 2013 Nov 9.

6.

Functional characterization of nuclear localization and export signals in hepatitis C virus proteins and their role in the membranous web.

Levin A, Neufeldt CJ, Pang D, Wilson K, Loewen-Dobler D, Joyce MA, Wozniak RW, Tyrrell DL.

PLoS One. 2014 Dec 8;9(12):e114629. doi: 10.1371/journal.pone.0114629. eCollection 2014.

7.

The role of interleukin-22 in hepatitis C virus infection.

Dambacher J, Beigel F, Zitzmann K, Heeg MH, Göke B, Diepolder HM, Auernhammer CJ, Brand S.

Cytokine. 2008 Mar;41(3):209-16. doi: 10.1016/j.cyto.2007.11.016. Epub 2008 Jan 11.

PMID:
18191408
8.

Structure-based glycoengineering of interferon lambda 4 enhances its productivity and anti-viral potency.

Chung JH, Hong SH, Seo N, Kim TS, An HJ, Lee P, Shin EC, Kim HM.

Cytokine. 2019 Aug 31;125:154833. doi: 10.1016/j.cyto.2019.154833. [Epub ahead of print]

PMID:
31479875
9.

TNF-α Induced by Hepatitis C Virus via TLR7 and TLR8 in Hepatocytes Supports Interferon Signaling via an Autocrine Mechanism.

Lee J, Tian Y, Chan ST, Kim JY, Cho C, Ou JH.

PLoS Pathog. 2015 May 29;11(5):e1004937. doi: 10.1371/journal.ppat.1004937. eCollection 2015 May.

10.

Interference of HCV replication by cell penetrable human monoclonal scFv specific to NS5B polymerase.

Thueng-in K, Thanongsaksrikul J, Jittavisutthikul S, Seesuay W, Chulanetra M, Sakolvaree Y, Srimanote P, Chaicumpa W.

MAbs. 2014;6(5):1327-39. doi: 10.4161/mabs.29978.

11.

9-cis retinoic acid enhances the antiviral effect of interferon on hepatitis C virus replication through increased expression of type I interferon receptor.

Hamamoto S, Fukuda R, Ishimura N, Rumi MA, Kazumori H, Uchida Y, Kadowaki Y, Ishihara S, Kinoshita Y.

J Lab Clin Med. 2003 Jan;141(1):58-66.

PMID:
12518169
12.

Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells.

Lauber C, Vieyres G, Terczyńska-Dyla E, Anggakusuma, Dijkman R, Gad HH, Akhtar H, Geffers R, Vondran FW, Thiel V, Kaderali L, Pietschmann T, Hartmann R.

Genes Immun. 2015 Sep;16(6):414-21. doi: 10.1038/gene.2015.23. Epub 2015 Jun 11.

PMID:
26066369
13.

Interferon alpha decreases expression of human scavenger receptor class BI, a possible HCV receptor in hepatocytes.

Murao K, Imachi H, Yu X, Cao WM, Nishiuchi T, Chen K, Li J, Ahmed RA, Wong NC, Ishida T.

Gut. 2008 May;57(5):664-71. Epub 2007 Nov 12.

PMID:
17998316
14.

Thromboxane A2 synthase inhibitors prevent production of infectious hepatitis C virus in mice with humanized livers.

Abe Y, Aly HH, Hiraga N, Imamura M, Wakita T, Shimotohno K, Chayama K, Hijikata M.

Gastroenterology. 2013 Sep;145(3):658-67.e11. doi: 10.1053/j.gastro.2013.05.014. Epub 2013 May 16.

PMID:
23684750
15.

Lymphocytes degranulation in liver in hepatitis C virus carriers is associated with IFNL4 polymorphisms and ALT levels.

Jouvin-Marche E, Macek Jílková Z, Thelu MA, Marche H, Fugier E, Van Campenhout N, Hoang XS, Marlu A, Sturm N, Callanan M, Leroy V, Zarski JP, Marche PN.

J Infect Dis. 2014 Jun 15;209(12):1907-15. doi: 10.1093/infdis/jiu016. Epub 2014 Jan 9.

PMID:
24415789
16.

Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon- alpha.

Tanabe Y, Sakamoto N, Enomoto N, Kurosaki M, Ueda E, Maekawa S, Yamashiro T, Nakagawa M, Chen CH, Kanazawa N, Kakinuma S, Watanabe M.

J Infect Dis. 2004 Apr 1;189(7):1129-39. Epub 2004 Mar 16.

PMID:
15031779
17.

A screen for genetic suppressor elements of hepatitis C virus identifies a supercharged protein inhibitor of viral replication.

Simeon RL, Chen Z.

PLoS One. 2013 Dec 31;8(12):e84022. doi: 10.1371/journal.pone.0084022. eCollection 2013.

18.

The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.

Logsdon NJ, Jones BC, Allman JC, Izotova L, Schwartz B, Pestka S, Walter MR.

J Mol Biol. 2004 Sep 10;342(2):503-14.

PMID:
15327950
19.

Hepatitis C virus replication in mouse cells is restricted by IFN-dependent and -independent mechanisms.

Nandakumar R, Finsterbusch K, Lipps C, Neumann B, Grashoff M, Nair S, Hochnadel I, Lienenklaus S, Wappler I, Steinmann E, Hauser H, Pietschmann T, Kröger A.

Gastroenterology. 2013 Dec;145(6):1414-23.e1. doi: 10.1053/j.gastro.2013.08.037. Epub 2013 Aug 21.

PMID:
23973921
20.

Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture.

Kurt R, Chandra PK, Aboulnasr F, Panigrahi R, Ferraris P, Aydin Y, Reiss K, Wu T, Balart LA, Dash S.

PLoS One. 2015 May 11;10(5):e0125962. doi: 10.1371/journal.pone.0125962. eCollection 2015.

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