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Items: 1 to 20 of 98

1.

Role of leptin-mediated colonic inflammation in defense against Clostridium difficile colitis.

Madan R, Guo X, Naylor C, Buonomo EL, Mackay D, Noor Z, Concannon P, Scully KW, Pramoonjago P, Kolling GL, Warren CA, Duggal P, Petri WA Jr.

Infect Immun. 2014 Jan;82(1):341-9. doi: 10.1128/IAI.00972-13. Epub 2013 Oct 28.

2.

Role of GM-CSF in the inflammatory cytokine network that regulates neutrophil influx into the colonic mucosa during Clostridium difficile infection in mice.

McDermott AJ, Frank CR, Falkowski NR, McDonald RA, Young VB, Huffnagle GB.

Gut Microbes. 2014 Jul 1;5(4):476-84. doi: 10.4161/gmic.29964. Epub 2014 Jul 21.

PMID:
25045999
3.

Role of interleukin 23 signaling in Clostridium difficile colitis.

Buonomo EL, Madan R, Pramoonjago P, Li L, Okusa MD, Petri WA Jr.

J Infect Dis. 2013 Sep;208(6):917-20. doi: 10.1093/infdis/jit277. Epub 2013 Jun 17.

4.

Leptin and mucosal immunity.

Mackey-Lawrence NM, Petri WA Jr.

Mucosal Immunol. 2012 Sep;5(5):472-9. doi: 10.1038/mi.2012.40. Epub 2012 Jun 13. Review.

5.

Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice.

Sadighi Akha AA, McDermott AJ, Theriot CM, Carlson PE Jr, Frank CR, McDonald RA, Falkowski NR, Bergin IL, Young VB, Huffnagle GB.

Immunology. 2015 Apr;144(4):587-97. doi: 10.1111/imm.12414.

6.

Leptin acts independently of food intake to modulate gut microbial composition in male mice.

Rajala MW, Patterson CM, Opp JS, Foltin SK, Young VB, Myers MG Jr.

Endocrinology. 2014 Mar;155(3):748-57. doi: 10.1210/en.2013-1085. Epub 2014 Jan 1.

7.

Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica.

Guo X, Roberts MR, Becker SM, Podd B, Zhang Y, Chua SC Jr, Myers MG Jr, Duggal P, Houpt ER, Petri WA Jr.

Mucosal Immunol. 2011 May;4(3):294-303. doi: 10.1038/mi.2010.76. Epub 2010 Dec 1.

8.

Effect of the leptin receptor Q223R polymorphism on the host transcriptome following infection with Entamoeba histolytica.

Mackey-Lawrence NM, Guo X, Sturdevant DE, Virtaneva K, Hernandez MM, Houpt E, Sher A, Porcella SF, Petri WA Jr.

Infect Immun. 2013 May;81(5):1460-70. doi: 10.1128/IAI.01383-12. Epub 2013 Feb 19. Erratum in: Infect Immun. 2013 Nov;81(11):4322.

9.

The role of Gr-1(+) cells and tumour necrosis factor-α signalling during Clostridium difficile colitis in mice.

McDermott AJ, Higdon KE, Muraglia R, Erb-Downward JR, Falkowski NR, McDonald RA, Young VB, Huffnagle GB.

Immunology. 2015 Apr;144(4):704-16. doi: 10.1111/imm.12425.

10.

Leptin receptor mutation results in defective neutrophil recruitment to the colon during Entamoeba histolytica infection.

Naylor C, Burgess S, Madan R, Buonomo E, Razzaq K, Ralston K, Petri WA Jr.

MBio. 2014 Dec 16;5(6). pii: e02046-14. doi: 10.1128/mBio.02046-14.

11.

Role of interferon-γ and inflammatory monocytes in driving colonic inflammation during acute Clostridium difficile infection in mice.

McDermott AJ, Falkowski NR, McDonald RA, Frank CR, Pandit CR, Young VB, Huffnagle GB.

Immunology. 2017 Apr;150(4):468-477. doi: 10.1111/imm.12700. Epub 2017 Jan 30.

PMID:
27995603
12.

Nucleotide-binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen.

Hasegawa M, Yamazaki T, Kamada N, Tawaratsumida K, Kim YG, Núñez G, Inohara N.

J Immunol. 2011 Apr 15;186(8):4872-80. doi: 10.4049/jimmunol.1003761. Epub 2011 Mar 16.

13.

Clostridium difficile-induced colitis in mice is independent of leukotrienes.

Trindade BC, Theriot CM, Leslie JL, Carlson PE Jr, Bergin IL, Peters-Golden M, Young VB, Aronoff DM.

Anaerobe. 2014 Dec;30:90-8. doi: 10.1016/j.anaerobe.2014.09.006. Epub 2014 Sep 16.

14.

Leptin receptor-induced STAT3-independent signaling pathways are protective against atherosclerosis in a murine model of obesity and hyperlipidemia.

Luo W, Bodary PF, Shen Y, Wickenheiser KJ, Ohman MK, Guo C, Bahrou KL, Myers MG Jr, Eitzman DT.

Atherosclerosis. 2011 Jan;214(1):81-5. doi: 10.1016/j.atherosclerosis.2010.10.009. Epub 2010 Oct 16.

15.

Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitis.

Jarchum I, Liu M, Shi C, Equinda M, Pamer EG.

Infect Immun. 2012 Sep;80(9):2989-96. doi: 10.1128/IAI.00448-12. Epub 2012 Jun 11.

16.

Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance.

Bodary PF, Shen Y, Ohman M, Bahrou KL, Vargas FB, Cudney SS, Wickenheiser KJ, Myers MG Jr, Eitzman DT.

Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):70-6. Epub 2006 Nov 9.

17.

Interleukin-23 (IL-23), independent of IL-17 and IL-22, drives neutrophil recruitment and innate inflammation during Clostridium difficile colitis in mice.

McDermott AJ, Falkowski NR, McDonald RA, Pandit CR, Young VB, Huffnagle GB.

Immunology. 2016 Jan;147(1):114-24. doi: 10.1111/imm.12545. Epub 2015 Dec 2.

18.

Disruption of leptin receptor-STAT3 signaling enhances leukotriene production and pulmonary host defense against pneumococcal pneumonia.

Mancuso P, Peters-Golden M, Goel D, Goldberg J, Brock TG, Greenwald-Yarnell M, Myers MG Jr.

J Immunol. 2011 Jan 15;186(2):1081-90. doi: 10.4049/jimmunol.1001470. Epub 2010 Dec 10.

19.

Protection from Clostridium difficile infection in CD4 T Cell- and polymeric immunoglobulin receptor-deficient mice.

Johnston PF, Gerding DN, Knight KL.

Infect Immun. 2014 Feb;82(2):522-31. doi: 10.1128/IAI.01273-13. Epub 2013 Nov 11.

20.

Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis.

Buffie CG, Jarchum I, Equinda M, Lipuma L, Gobourne A, Viale A, Ubeda C, Xavier J, Pamer EG.

Infect Immun. 2012 Jan;80(1):62-73. doi: 10.1128/IAI.05496-11. Epub 2011 Oct 17.

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