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Items: 1 to 20 of 149

1.

Kinetic flux profiling elucidates two independent acetyl-CoA biosynthetic pathways in Plasmodium falciparum.

Cobbold SA, Vaughan AM, Lewis IA, Painter HJ, Camargo N, Perlman DH, Fishbaugher M, Healer J, Cowman AF, Kappe SH, Llinás M.

J Biol Chem. 2013 Dec 20;288(51):36338-50. doi: 10.1074/jbc.M113.503557. Epub 2013 Oct 25.

2.

The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is located in the apicoplast.

Foth BJ, Stimmler LM, Handman E, Crabb BS, Hodder AN, McFadden GI.

Mol Microbiol. 2005 Jan;55(1):39-53.

3.

Branched tricarboxylic acid metabolism in Plasmodium falciparum.

Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M.

Nature. 2010 Aug 5;466(7307):774-8. doi: 10.1038/nature09301. Erratum in: Nature. 2011 Jan 20;469(7330):432. Retraction in: Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Nature. 2013 May 30;497(7451):652.

4.

Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum.

MacRae JI, Dixon MW, Dearnley MK, Chua HH, Chambers JM, Kenny S, Bottova I, Tilley L, McConville MJ.

BMC Biol. 2013 Jun 13;11:67. doi: 10.1186/1741-7007-11-67.

5.

Plasmodium falciparum possesses organelle-specific alpha-keto acid dehydrogenase complexes and lipoylation pathways.

Günther S, McMillan PJ, Wallace LJ, Müller S.

Biochem Soc Trans. 2005 Nov;33(Pt 5):977-80. Review.

PMID:
16246025
6.

c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.

Edmunds LR, Sharma L, Kang A, Lu J, Vockley J, Basu S, Uppala R, Goetzman ES, Beck ME, Scott D, Prochownik EV.

J Biol Chem. 2014 Sep 5;289(36):25382-92. doi: 10.1074/jbc.M114.580662. Epub 2014 Jul 22. Erratum in: J Biol Chem. 2015 Aug 14;290(33):20100.

7.

Engineering acetyl coenzyme A supply: functional expression of a bacterial pyruvate dehydrogenase complex in the cytosol of Saccharomyces cerevisiae.

Kozak BU, van Rossum HM, Luttik MA, Akeroyd M, Benjamin KR, Wu L, de Vries S, Daran JM, Pronk JT, van Maris AJ.

MBio. 2014 Oct 21;5(5):e01696-14. doi: 10.1128/mBio.01696-14.

9.
10.

The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?

Sugden MC, Holness MJ.

Islets. 2011 Nov-Dec;3(6):302-19. doi: 10.4161/isl.3.6.17806. Epub 2011 Nov 1. Review.

11.

Plasmodium pyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection.

Pei Y, Tarun AS, Vaughan AM, Herman RW, Soliman JM, Erickson-Wayman A, Kappe SH.

Mol Microbiol. 2010 Feb;75(4):957-71. doi: 10.1111/j.1365-2958.2009.07034.x.

12.

Acetyl-CoA synthesizing enzymes in cholinergic nerve terminals.

Sterri SH, Fonnum F.

J Neurochem. 1980 Jul;35(1):249-54.

PMID:
6108988
13.

Reduced effects of L-carnitine on glucose and fatty acid metabolism in myocytes isolated from diabetic rats.

Abdel-aleem S, Karim AM, Zarouk WA, Taylor DA, el-Awady MK, Lowe JE.

Horm Metab Res. 1997 Sep;29(9):430-5.

PMID:
9370110
14.

Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation.

Sharma N, Okere IC, Brunengraber DZ, McElfresh TA, King KL, Sterk JP, Huang H, Chandler MP, Stanley WC.

J Physiol. 2005 Jan 15;562(Pt 2):593-603. Epub 2004 Nov 18.

15.

BCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium berghei.

Oppenheim RD, Creek DJ, Macrae JI, Modrzynska KK, Pino P, Limenitakis J, Polonais V, Seeber F, Barrett MP, Billker O, McConville MJ, Soldati-Favre D.

PLoS Pathog. 2014 Jul 17;10(7):e1004263. doi: 10.1371/journal.ppat.1004263. eCollection 2014 Jul.

17.

Fatty acid synthesis and pyruvate metabolism pathways remain active in dihydroartemisinin-induced dormant ring stages of Plasmodium falciparum.

Chen N, LaCrue AN, Teuscher F, Waters NC, Gatton ML, Kyle DE, Cheng Q.

Antimicrob Agents Chemother. 2014 Aug;58(8):4773-81. doi: 10.1128/AAC.02647-14. Epub 2014 Jun 9.

18.

Alternative reactions at the interface of glycolysis and citric acid cycle in Saccharomyces cerevisiae.

van Rossum HM, Kozak BU, Niemeijer MS, Duine HJ, Luttik MA, Boer VM, Kötter P, Daran JM, van Maris AJ, Pronk JT.

FEMS Yeast Res. 2016 May;16(3). pii: fow017. doi: 10.1093/femsyr/fow017. Epub 2016 Feb 18.

PMID:
26895788
19.

The role of pyruvate dehydrogenase and acetyl-coenzyme A synthetase in fatty acid synthesis in developing Arabidopsis seeds.

Ke J, Behal RH, Back SL, Nikolau BJ, Wurtele ES, Oliver DJ.

Plant Physiol. 2000 Jun;123(2):497-508.

20.

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