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Items: 1 to 20 of 316

1.

Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1-Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice.

Wei J, Zhang Y, Luo Y, Wang Z, Bi S, Song D, Dai Y, Wang T, Qiu L, Wen L, Yuan L, Yang JY.

Free Radic Biol Med. 2014 Feb;67:91-102. doi: 10.1016/j.freeradbiomed.2013.10.811. Epub 2013 Oct 24.

2.

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells.

Kato M, Arce L, Wang M, Putta S, Lanting L, Natarajan R.

Kidney Int. 2011 Aug;80(4):358-68. doi: 10.1038/ki.2011.43. Epub 2011 Mar 9.

3.

miR-200a Prevents renal fibrogenesis through repression of TGF-β2 expression.

Wang B, Koh P, Winbanks C, Coughlan MT, McClelland A, Watson A, Jandeleit-Dahm K, Burns WC, Thomas MC, Cooper ME, Kantharidis P.

Diabetes. 2011 Jan;60(1):280-7. doi: 10.2337/db10-0892. Epub 2010 Oct 15.

4.

Molecular events in matrix protein metabolism in the aging kidney.

Sataranatarajan K, Feliers D, Mariappan MM, Lee HJ, Lee MJ, Day RT, Yalamanchili HB, Choudhury GG, Barnes JL, Van Remmen H, Richardson A, Kasinath BS.

Aging Cell. 2012 Dec;11(6):1065-73. doi: 10.1111/acel.12008. Epub 2012 Oct 19.

5.
6.

Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells.

Huang K, Chen C, Hao J, Huang J, Wang S, Liu P, Huang H.

Mol Cell Endocrinol. 2015 Jan 5;399:178-89. doi: 10.1016/j.mce.2014.08.014. Epub 2014 Sep 2.

PMID:
25192797
7.

Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy.

Putta S, Lanting L, Sun G, Lawson G, Kato M, Natarajan R.

J Am Soc Nephrol. 2012 Mar;23(3):458-69. doi: 10.1681/ASN.2011050485. Epub 2012 Jan 5.

8.

miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells.

Eades G, Yang M, Yao Y, Zhang Y, Zhou Q.

J Biol Chem. 2011 Nov 25;286(47):40725-33. doi: 10.1074/jbc.M111.275495. Epub 2011 Sep 16.

9.

Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma.

Cong N, Du P, Zhang A, Shen F, Su J, Pu P, Wang T, Zjang J, Kang C, Zhang Q.

Oncol Rep. 2013 Apr;29(4):1579-87. doi: 10.3892/or.2013.2267. Epub 2013 Jan 31.

PMID:
23381389
10.

Methylseleninic acid activates Keap1/Nrf2 pathway via up-regulating miR-200a in human oesophageal squamous cell carcinoma cells.

Liu M, Hu C, Xu Q, Chen L, Ma K, Xu N, Zhu H.

Biosci Rep. 2015 Sep 4;35(5). pii: e00256. doi: 10.1042/BSR20150092.

11.

High glucose induces renal tubular epithelial injury via Sirt1/NF-kappaB/microR-29/Keap1 signal pathway.

Zhou L, Xu DY, Sha WG, Shen L, Lu GY, Yin X, Wang MJ.

J Transl Med. 2015 Nov 9;13:352. doi: 10.1186/s12967-015-0710-y.

12.

Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells.

Huang K, Huang J, Xie X, Wang S, Chen C, Shen X, Liu P, Huang H.

Free Radic Biol Med. 2013 Dec;65:528-40. doi: 10.1016/j.freeradbiomed.2013.07.029. Epub 2013 Jul 24.

PMID:
23891678
13.

Inhibitory role of the KEAP1-NRF2 pathway in TGFβ1-stimulated renal epithelial transition to fibroblastic cells: a modulatory effect on SMAD signaling.

Ryoo IG, Ha H, Kwak MK.

PLoS One. 2014 Apr 1;9(4):e93265. doi: 10.1371/journal.pone.0093265. eCollection 2014.

14.

Regulation of transforming growth factor β1-dependent aldose reductase expression by the Nrf2 signal pathway in human mesangial cells.

Wang F, Tian F, Whitman SA, Zhang DD, Nishinaka T, Zhang N, Jiang T.

Eur J Cell Biol. 2012 Oct;91(10):774-81. doi: 10.1016/j.ejcb.2012.07.004. Epub 2012 Aug 27.

PMID:
22951256
15.

MicroRNA-200a controls Nrf2 activation by target Keap1 in hepatic stellate cell proliferation and fibrosis.

Yang JJ, Tao H, Hu W, Liu LP, Shi KH, Deng ZY, Li J.

Cell Signal. 2014 Nov;26(11):2381-9. doi: 10.1016/j.cellsig.2014.07.016. Epub 2014 Jul 15.

PMID:
25049078
16.

MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes.

Dey N, Das F, Mariappan MM, Mandal CC, Ghosh-Choudhury N, Kasinath BS, Choudhury GG.

J Biol Chem. 2011 Jul 22;286(29):25586-603. doi: 10.1074/jbc.M110.208066. Epub 2011 May 25.

17.

Therapeutic potential of Nrf2 activators in streptozotocin-induced diabetic nephropathy.

Zheng H, Whitman SA, Wu W, Wondrak GT, Wong PK, Fang D, Zhang DD.

Diabetes. 2011 Nov;60(11):3055-66. doi: 10.2337/db11-0807.

18.

Restoration of Nrf2 Signaling Normalizes the Regenerative Niche.

Soares MA, Cohen OD, Low YC, Sartor RA, Ellison T, Anil U, Anzai L, Chang JB, Saadeh PB, Rabbani PS, Ceradini DJ.

Diabetes. 2016 Mar;65(3):633-46. doi: 10.2337/db15-0453. Epub 2015 Dec 8.

19.

The Keap1-Nrf2 system prevents onset of diabetes mellitus.

Uruno A, Furusawa Y, Yagishita Y, Fukutomi T, Muramatsu H, Negishi T, Sugawara A, Kensler TW, Yamamoto M.

Mol Cell Biol. 2013 Aug;33(15):2996-3010. doi: 10.1128/MCB.00225-13. Epub 2013 May 28.

20.

Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b.

Wang B, Jha JC, Hagiwara S, McClelland AD, Jandeleit-Dahm K, Thomas MC, Cooper ME, Kantharidis P.

Kidney Int. 2014 Feb;85(2):352-61. doi: 10.1038/ki.2013.372. Epub 2013 Oct 2.

PMID:
24088962

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