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Items: 1 to 20 of 418

1.

SAMHD1 host restriction factor: a link with innate immune sensing of retrovirus infection.

Sze A, Olagnier D, Lin R, van Grevenynghe J, Hiscott J.

J Mol Biol. 2013 Dec 13;425(24):4981-94. doi: 10.1016/j.jmb.2013.10.022. Epub 2013 Oct 23. Review.

PMID:
24161438
2.

SAMHD1 knockout mice: modeling retrovirus restriction in vivo.

Wu L.

Retrovirology. 2013 Nov 20;10:142. doi: 10.1186/1742-4690-10-142.

3.

SAMHD1: a novel antiviral factor in intrinsic immunity.

Chen Z, Zhang L, Ying S.

Future Microbiol. 2012 Sep;7(9):1117-26. doi: 10.2217/fmb.12.81. Review.

PMID:
22953710
4.

Restricting HIV the SAMHD1 way: through nucleotide starvation.

Ayinde D, Casartelli N, Schwartz O.

Nat Rev Microbiol. 2012 Oct;10(10):675-80. doi: 10.1038/nrmicro2862. Epub 2012 Aug 28.

PMID:
22926205
5.

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burggraf M, Schenkova K, Ambiel I, Wabnitz G, Gramberg T, Panitz S, Flory E, Landau NR, Sertel S, Rutsch F, Lasitschka F, Kim B, König R, Fackler OT, Keppler OT.

Nat Med. 2012 Nov;18(11):1682-7. doi: 10.1038/nm.2964.

6.

Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1.

White TE, Brandariz-Nuñez A, Valle-Casuso JC, Amie S, Nguyen L, Kim B, Brojatsch J, Diaz-Griffero F.

Virology. 2013 Feb 5;436(1):81-90. doi: 10.1016/j.virol.2012.10.029. Epub 2012 Nov 13.

7.

Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase.

Powell RD, Holland PJ, Hollis T, Perrino FW.

J Biol Chem. 2011 Dec 23;286(51):43596-600. doi: 10.1074/jbc.C111.317628. Epub 2011 Nov 7.

8.

SAMHD1: at the crossroads of cell proliferation, immune responses, and virus restriction.

Ballana E, Esté JA.

Trends Microbiol. 2015 Nov;23(11):680-92. doi: 10.1016/j.tim.2015.08.002. Epub 2015 Oct 1. Review.

PMID:
26439297
9.

Degradation of SAMHD1 by Vpx Is Independent of Uncoating.

Jáuregui P, Logue EC, Schultz ML, Fung S, Landau NR.

J Virol. 2015 May;89(10):5701-13. doi: 10.1128/JVI.03575-14. Epub 2015 Mar 11.

10.

AIDS/HIV. HIV interplay with SAMHD1.

Schaller T, Goujon C, Malim MH.

Science. 2012 Mar 16;335(6074):1313-4. doi: 10.1126/science.1221057. No abstract available.

PMID:
22422971
11.

SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors.

Ballana E, Badia R, Terradas G, Torres-Torronteras J, Ruiz A, Pauls E, Riveira-Muñoz E, Clotet B, Martí R, Esté JA.

Antimicrob Agents Chemother. 2014 Aug;58(8):4804-13. doi: 10.1128/AAC.03145-14. Epub 2014 Jun 9.

12.

Emerging role of the host restriction factor tetherin in viral immune sensing.

Hotter D, Sauter D, Kirchhoff F.

J Mol Biol. 2013 Dec 13;425(24):4956-64. doi: 10.1016/j.jmb.2013.09.029. Epub 2013 Sep 26. Review.

PMID:
24075872
13.

Nucleotide embargo by SAMHD1: a strategy to block retroviral infection.

Pauls E, Ballana E, Esté JA.

Antiviral Res. 2013 Feb;97(2):180-2. doi: 10.1016/j.antiviral.2012.12.009. Epub 2012 Dec 21.

PMID:
23266292
14.

The efficiency of Vpx-mediated SAMHD1 antagonism does not correlate with the potency of viral control in HIV-2-infected individuals.

Yu H, Usmani SM, Borch A, Krämer J, Stürzel CM, Khalid M, Li X, Krnavek D, van der Ende ME, Osterhaus AD, Gruters RA, Kirchhoff F.

Retrovirology. 2013 Mar 5;10:27. doi: 10.1186/1742-4690-10-27.

15.

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.

Beloglazova N, Flick R, Tchigvintsev A, Brown G, Popovic A, Nocek B, Yakunin AF.

J Biol Chem. 2013 Mar 22;288(12):8101-10. doi: 10.1074/jbc.M112.431148. Epub 2013 Jan 30.

16.

SAMHD1 in Retroviral Restriction and Innate Immune Sensing--Should We Leash the Hound?

Herrmann A, Happel AU, Gramberg T.

Curr HIV Res. 2016;14(3):225-34. Review.

PMID:
26957197
17.

SAMHD1 specifically restricts retroviruses through its RNase activity.

Choi J, Ryoo J, Oh C, Hwang S, Ahn K.

Retrovirology. 2015 Jun 2;12:46. doi: 10.1186/s12977-015-0174-4.

18.

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.

Goldstone DC, Ennis-Adeniran V, Hedden JJ, Groom HC, Rice GI, Christodoulou E, Walker PA, Kelly G, Haire LF, Yap MW, de Carvalho LP, Stoye JP, Crow YJ, Taylor IA, Webb M.

Nature. 2011 Nov 6;480(7377):379-82. doi: 10.1038/nature10623.

PMID:
22056990
19.

Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1.

St Gelais C, de Silva S, Hach JC, White TE, Diaz-Griffero F, Yount JS, Wu L.

J Virol. 2014 May;88(10):5834-44. doi: 10.1128/JVI.00155-14. Epub 2014 Mar 12. Erratum in: J Virol. 2014 Jul;88(13):7689.

20.

SAMHD1 prevents autoimmunity by maintaining genome stability.

Kretschmer S, Wolf C, König N, Staroske W, Guck J, Häusler M, Luksch H, Nguyen LA, Kim B, Alexopoulou D, Dahl A, Rapp A, Cardoso MC, Shevchenko A, Lee-Kirsch MA.

Ann Rheum Dis. 2015 Mar;74(3):e17. doi: 10.1136/annrheumdis-2013-204845. Epub 2014 Jan 20.

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