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Items: 1 to 20 of 111

1.

Regulator of calcineurin 1 modulates expression of innate anxiety and anxiogenic responses to selective serotonin reuptake inhibitor treatment.

Hoeffer CA, Wong H, Cain P, Levenga J, Cowansage KK, Choi Y, Davy C, Majmundar N, McMillan DR, Rothermel BA, Klann E.

J Neurosci. 2013 Oct 23;33(43):16930-44. doi: 10.1523/JNEUROSCI.3513-12.2013.

2.

The regulator of calcineurin 1 (RCAN1/DSCR1) activates the cAMP response element-binding protein (CREB) pathway.

Kim SS, Seo SR.

J Biol Chem. 2011 Oct 28;286(43):37841-8. doi: 10.1074/jbc.M111.232165. Epub 2011 Sep 2.

3.

CREB activates proteasomal degradation of DSCR1/RCAN1.

Seo SR, Chung KC.

FEBS Lett. 2008 Jun 11;582(13):1889-93. doi: 10.1016/j.febslet.2008.04.059. Epub 2008 May 15.

4.

Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation.

Jung MS, Park JH, Ryu YS, Choi SH, Yoon SH, Kwen MY, Oh JY, Song WJ, Chung SH.

J Biol Chem. 2011 Nov 18;286(46):40401-12. doi: 10.1074/jbc.M111.253971. Epub 2011 Sep 30.

5.

PKA regulates calcineurin function through the phosphorylation of RCAN1: identification of a novel phosphorylation site.

Kim SS, Lee EH, Lee K, Jo SH, Seo SR.

Biochem Biophys Res Commun. 2015 Apr 17;459(4):604-9. doi: 10.1016/j.bbrc.2015.02.155. Epub 2015 Mar 7.

PMID:
25753203
6.

Regulator of calcineurin 1 controls growth plasticity of adult pancreas.

Gurda GT, Crozier SJ, Ji B, Ernst SA, Logsdon CD, Rothermel BA, Williams JA.

Gastroenterology. 2010 Aug;139(2):609-19, 619.e1-6. doi: 10.1053/j.gastro.2010.04.050. Epub 2010 Jun 18.

7.

Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin defines a signalling nodal control point.

Liu Q, Busby JC, Molkentin JD.

Nat Cell Biol. 2009 Feb;11(2):154-61. doi: 10.1038/ncb1823. Epub 2009 Jan 11.

8.

p38α MAP kinase phosphorylates RCAN1 and regulates its interaction with calcineurin.

Ma L, Tang H, Ren Y, Deng H, Wu J, Wang Z.

Sci China Life Sci. 2012 Jul;55(7):559-66. doi: 10.1007/s11427-012-4340-9. Epub 2012 Aug 4.

PMID:
22864830
9.

The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling.

Hoeffer CA, Dey A, Sachan N, Wong H, Patterson RJ, Shelton JM, Richardson JA, Klann E, Rothermel BA.

J Neurosci. 2007 Nov 28;27(48):13161-72.

10.

The CCAAT/enhancer binding protein beta (C/EBPbeta) cooperates with NFAT to control expression of the calcineurin regulatory protein RCAN1-4.

Oh M, Dey A, Gerard RD, Hill JA, Rothermel BA.

J Biol Chem. 2010 May 28;285(22):16623-31. doi: 10.1074/jbc.M109.098236. Epub 2010 Apr 6.

11.

Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion.

Rotter D, Grinsfelder DB, Parra V, Pedrozo Z, Singh S, Sachan N, Rothermel BA.

J Mol Cell Cardiol. 2014 Sep;74:103-11. doi: 10.1016/j.yjmcc.2014.05.004. Epub 2014 May 15.

12.

RCAN1 is an important mediator of glucocorticoid-induced apoptosis in human leukemic cells.

Nagao K, Iwai Y, Miyashita T.

PLoS One. 2012;7(11):e49926. doi: 10.1371/journal.pone.0049926. Epub 2012 Nov 21.

13.

VEGF stimulates RCAN1.4 expression in endothelial cells via a pathway requiring Ca2+/calcineurin and protein kinase C-delta.

Holmes K, Chapman E, See V, Cross MJ.

PLoS One. 2010 Jul 6;5(7):e11435. doi: 10.1371/journal.pone.0011435.

14.

Protein kinase A phosphorylates Down syndrome critical region 1 (RCAN1).

Kim SS, Oh Y, Chung KC, Seo SR.

Biochem Biophys Res Commun. 2012 Feb 24;418(4):657-61. doi: 10.1016/j.bbrc.2012.01.071. Epub 2012 Jan 24.

PMID:
22293192
15.

A hidden incoherent switch regulates RCAN1 in the calcineurin-NFAT signaling network.

Shin SY, Yang HW, Kim JR, Heo WD, Cho KH.

J Cell Sci. 2011 Jan 1;124(Pt 1):82-90. doi: 10.1242/jcs.076034.

16.

Regulator of calcineurin 1 (Rcan1) has a protective role in brain ischemia/reperfusion injury.

Sobrado M, Ramirez BG, Neria F, Lizasoain I, Arbones ML, Minami T, Redondo JM, Moro MA, Cano E.

J Neuroinflammation. 2012 Mar 7;9:48. doi: 10.1186/1742-2094-9-48.

17.

Enzymatic and thermodynamic analysis of calcineurin inhibition by RCAN1.

Ma Y, Jiang G, Wang Q, Sun Y, Zhao Y, Tong L, Luo J.

Int J Biol Macromol. 2015 Jan;72:254-60. doi: 10.1016/j.ijbiomac.2014.08.042. Epub 2014 Sep 1.

PMID:
25193101
18.

Brain expression of the calcineurin inhibitor RCAN1 (Adapt78).

Mitchell AN, Jayakumar L, Koleilat I, Qian J, Sheehan C, Bhoiwala D, Hushmendy SF, Heuring JM, Crawford DR.

Arch Biochem Biophys. 2007 Nov 15;467(2):185-92. Epub 2007 Sep 7.

PMID:
17910944
19.

DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease.

Keating DJ, Dubach D, Zanin MP, Yu Y, Martin K, Zhao YF, Chen C, Porta S, Arbonés ML, Mittaz L, Pritchard MA.

Hum Mol Genet. 2008 Apr 1;17(7):1020-30. doi: 10.1093/hmg/ddm374. Epub 2008 Jan 7.

PMID:
18180251
20.

Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene.

Belmont PJ, Tadimalla A, Chen WJ, Martindale JJ, Thuerauf DJ, Marcinko M, Gude N, Sussman MA, Glembotski CC.

J Biol Chem. 2008 May 16;283(20):14012-21. doi: 10.1074/jbc.M709776200. Epub 2008 Mar 3.

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