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Items: 1 to 20 of 104

1.

Conjugation of peptide nucleic acid with a pyrrole/imidazole polyamide to specifically recognize and cleave DNA.

Kameshima W, Ishizuka T, Minoshima M, Yamamoto M, Sugiyama H, Xu Y, Komiyama M.

Angew Chem Int Ed Engl. 2013 Dec 16;52(51):13681-4. doi: 10.1002/anie.201305489. Epub 2013 Oct 23.

PMID:
24155125
2.

Sequence-specific DNA recognition by cyclic pyrrole-imidazole cysteine-derived polyamide dimers.

Yamamoto M, Bando T, Morinaga H, Kawamoto Y, Hashiya K, Sugiyama H.

Chemistry. 2014 Jan 13;20(3):752-9. doi: 10.1002/chem.201302482. Epub 2013 Dec 11.

PMID:
24339258
3.

Molecular design of hairpin imidazole-pyrrole polyamide for effective DNA alkylation.

Bando T, Narita A, Saito I, Sugiyama H.

Nucleic Acids Res Suppl. 2001;(1):225-6.

PMID:
12836346
4.

Sequence specific recognition of DNA by tailor-made hairpin conjugates of achiral seco-cyclopropaneindoline-2-benzofurancarboxamide and pyrrole-imidazole polyamides.

Price CA, Lingerfelt BM, Handl HL, Kiakos K, Hartley JA, Lee M.

Bioorg Med Chem Lett. 2005 Jun 15;15(12):3151-6.

PMID:
15876536
5.

Molecular design of hairpin pyrrole-imidazole polyamides possessing sequence specific DNA alkylating moiety.

Narita A, Bando T, Sugiyama H.

Nucleic Acids Res Suppl. 2003;(3):119-20.

PMID:
14510409
6.

Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5'-GCGC-3'.

Han YW, Kashiwazaki G, Morinaga H, Matsumoto T, Hashiya K, Bando T, Harada Y, Sugiyama H.

Bioorg Med Chem. 2013 Sep 1;21(17):5436-41. doi: 10.1016/j.bmc.2013.06.005. Epub 2013 Jun 11.

7.

Hx-amides: DNA sequence recognition by the fluorescent Hx (p-anisylbenzimidazole)•pyrrole and Hx•imidazole pairings.

Satam V, Patil P, Babu B, Gregory M, Bowerman M, Savagian M, Lee M, Tzou S, Olson K, Liu Y, Ramos J, Wilson WD, Bingham JP, Kiakos K, Hartley JA, Lee M.

Bioorg Med Chem Lett. 2013 Mar 15;23(6):1699-702. doi: 10.1016/j.bmcl.2013.01.075. Epub 2013 Jan 25.

PMID:
23395654
8.

Recognition of DNA by designed ligands at subnanomolar concentrations.

Trauger JW, Baird EE, Dervan PB.

Nature. 1996 Aug 8;382(6591):559-61.

PMID:
8700233
9.

DNA sequence recognition in the minor groove by hairpin pyrrole polyamide-Hoechst 33258 analogue conjugate.

Reddy PM, Dexter R, Bruice TC.

Bioorg Med Chem Lett. 2004 Jul 16;14(14):3803-7.

PMID:
15203166
10.

Sequence-specific DNA alkylation and transcriptional inhibition by long-chain hairpin pyrrole-imidazole polyamide-chlorambucil conjugates targeting CAG/CTG trinucleotide repeats.

Asamitsu S, Kawamoto Y, Hashiya F, Hashiya K, Yamamoto M, Kizaki S, Bando T, Sugiyama H.

Bioorg Med Chem. 2014 Sep 1;22(17):4646-57. doi: 10.1016/j.bmc.2014.07.019. Epub 2014 Jul 22.

PMID:
25127467
11.

Directed assembly of DNA-functionalized gold nanoparticles using pyrrole-imidazole polyamides.

Krpetić Z, Singh I, Su W, Guerrini L, Faulds K, Burley GA, Graham D.

J Am Chem Soc. 2012 May 23;134(20):8356-9. doi: 10.1021/ja3014924. Epub 2012 May 14.

PMID:
22559739
12.

Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.

Henry JA, Le NM, Nguyen B, Howard CM, Bailey SL, Horick SM, Buchmueller KL, Kotecha M, Hochhauser D, Hartley JA, Wilson WD, Lee M.

Biochemistry. 2004 Sep 28;43(38):12249-57.

PMID:
15379563
13.

Specific alkylation of human telomere repeats by hairpin pyrrole-imidazole polyamide.

Takahashi R, Bando T, Sugiyama H.

Bioorg Med Chem. 2003 Jun 12;11(12):2503-9.

PMID:
12757718
14.

Conjugation of a hairpin pyrrole-imidazole polyamide to a quinone methide for control of DNA cross-linking.

Kumar D, Veldhuyzen WF, Zhou Q, Rokita SE.

Bioconjug Chem. 2004 Jul-Aug;15(4):915-22.

PMID:
15264882
15.

Sequence-specific DNA alkylation targeting for Kras codon 13 mutation by pyrrole-imidazole polyamide seco-CBI conjugates.

Taylor RD, Asamitsu S, Takenaka T, Yamamoto M, Hashiya K, Kawamoto Y, Bando T, Nagase H, Sugiyama H.

Chemistry. 2014 Jan 27;20(5):1310-7. doi: 10.1002/chem.201303295. Epub 2013 Dec 30.

PMID:
24382626
16.

Pyrrole/imidazole-polyamide anchors for DNA tertiary interactions.

Schmidt TL, Heckel A.

Small. 2009 Jul;5(13):1517-20. doi: 10.1002/smll.200900147. No abstract available.

PMID:
19360724
17.

Sequence-selective single-molecule alkylation with a pyrrole-imidazole polyamide visualized in a DNA nanoscaffold.

Yoshidome T, Endo M, Kashiwazaki G, Hidaka K, Bando T, Sugiyama H.

J Am Chem Soc. 2012 Mar 14;134(10):4654-60. doi: 10.1021/ja209023u. Epub 2012 Feb 29.

PMID:
22320236
18.

Structural basis for G.C recognition in the DNA minor groove.

Kielkopf CL, Baird EE, Dervan PB, Rees DC.

Nat Struct Biol. 1998 Feb;5(2):104-9.

PMID:
9461074
19.

Sequence selective recognition of DNA by hairpin conjugates of a racemic seco-cyclopropaneindoline-2-benzofurancarboxamide and polyamides.

Toth JL, Price CA, Madsen EC, Handl HL, Hudson SJ, Hubbard RB 3rd, Bowen JP, Kiakos K, Hartley JA, Lee M.

Bioorg Med Chem Lett. 2002 Aug 19;12(16):2245-8.

PMID:
12127548
20.

Pyrrole-imidazole hairpin polyamides with high affinity at 5'-CGCG-3' DNA sequence; influence of cytosine methylation on binding.

Minoshima M, Bando T, Sasaki S, Fujimoto J, Sugiyama H.

Nucleic Acids Res. 2008 May;36(9):2889-94. doi: 10.1093/nar/gkn116. Epub 2008 Apr 1.

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