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Items: 1 to 20 of 133


Sesquiterpene lactones and their derivatives inhibit high glucose-induced NF-κB activation and MCP-1 and TGF-β1 expression in rat mesangial cells.

Jia QQ, Wang JC, Long J, Zhao Y, Chen SJ, Zhai JD, Wei LB, Zhang Q, Chen Y, Long HB.

Molecules. 2013 Oct 21;18(10):13061-77. doi: 10.3390/molecules181013061.


AOPPs induce MCP-1 expression by increasing ROS-mediated activation of the NF-κB pathway in rat mesangial cells: inhibition by sesquiterpene lactones.

Wang JC, Zhao Y, Chen SJ, Long J, Jia QQ, Zhai JD, Zhang Q, Chen Y, Long HB.

Cell Physiol Biochem. 2013;32(6):1867-77. doi: 10.1159/000356619. Epub 2013 Dec 20.


High glucose induces rat mesangial cells proliferation and MCP-1 expression via ROS-mediated activation of NF-κB pathway, which is inhibited by eleutheroside E.

Yang X, Wang Y, Gao G.

J Recept Signal Transduct Res. 2016;36(2):152-7. doi: 10.3109/10799893.2015.1061002. Epub 2015 Dec 7.


[Effects of parthenolide on high glucose-induced cell proliferation, NF-κB activation and MCP-1 expression in rat mesangial cells].

Xu Z, Jia Q, Li H, Wang J, Zhao Y, Chen S, Long H.

Nan Fang Yi Ke Da Xue Xue Bao. 2013 Oct;33(10):1471-3. Chinese.


Monocyte chemoattractant protein-1 has prosclerotic effects both in a mouse model of experimental diabetes and in vitro in human mesangial cells.

Giunti S, Tesch GH, Pinach S, Burt DJ, Cooper ME, Cavallo-Perin P, Camussi G, Gruden G.

Diabetologia. 2008 Jan;51(1):198-207. Epub 2007 Oct 30.


The anti-inflammation effect of Moutan Cortex on advanced glycation end products-induced rat mesangial cells dysfunction and High-glucose-fat diet and streptozotocin-induced diabetic nephropathy rats.

Zhang MH, Feng L, Zhu MM, Gu JF, Jiang J, Cheng XD, Ding SM, Wu C, Jia XB.

J Ethnopharmacol. 2014;151(1):591-600. doi: 10.1016/j.jep.2013.11.015. Epub 2013 Nov 21.


Emodin attenuates high glucose-induced TGF-β1 and fibronectin expression in mesangial cells through inhibition of NF-κB pathway.

Yang J, Zeng Z, Wu T, Yang Z, Liu B, Lan T.

Exp Cell Res. 2013 Dec 10;319(20):3182-9. doi: 10.1016/j.yexcr.2013.10.006. Epub 2013 Oct 15.


Sesquiterpene lactones inhibit advanced oxidation protein product-induced MCP-1 expression in podocytes via an IKK/NF-κB-dependent mechanism.

Zhao Y, Chen SJ, Wang JC, Niu HX, Jia QQ, Chen XW, Du XY, Lu L, Huang B, Zhang Q, Chen Y, Long HB.

Oxid Med Cell Longev. 2015;2015:934058. doi: 10.1155/2015/934058. Epub 2015 Jan 12.


MCP-1/CCR2 system is involved in high glucose-induced fibronectin and type IV collagen expression in cultured mesangial cells.

Park J, Ryu DR, Li JJ, Jung DS, Kwak SJ, Lee SH, Yoo TH, Han SH, Lee JE, Kim DK, Moon SJ, Kim K, Han DS, Kang SW.

Am J Physiol Renal Physiol. 2008 Sep;295(3):F749-57. doi: 10.1152/ajprenal.00547.2007. Epub 2008 Jun 25.


Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting the activation of RhoA/ROCK signaling.

Xie X, Chang X, Chen L, Huang K, Huang J, Wang S, Shen X, Liu P, Huang H.

Mol Cell Endocrinol. 2013 Dec 5;381(1-2):56-65. doi: 10.1016/j.mce.2013.07.019. Epub 2013 Jul 26.


Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-κB signaling pathway in vivo and in vitro.

Wang Y, Nie M, Lu Y, Wang R, Li J, Yang B, Xia M, Zhang H, Li X.

Int J Mol Med. 2015 Apr;35(4):1067-73. doi: 10.3892/ijmm.2015.2095. Epub 2015 Feb 9.


Valsartan attenuated oxidative stress, decreased MCP-1 and TGF-β1 expression in glomerular mesangial and epithelial cells induced by high-glucose levels.

Jiao B, Wang YS, Cheng YN, Gao JJ, Zhang QZ.

Biosci Trends. 2011 Aug;5(4):173-81. doi: 10.5582/bst.2011.v5.4.173.


Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide.

Yuan P, Xue H, Zhou L, Qu L, Li C, Wang Z, Ni J, Yu C, Yao T, Huang Y, Wang R, Lu L.

Nephrol Dial Transplant. 2011 Jul;26(7):2119-26. doi: 10.1093/ndt/gfq749. Epub 2011 Jan 5.


Quercetin suppresses NF-κB and MCP-1 expression in a high glucose-induced human mesangial cell proliferation model.

Chen P, Shi Q, Xu X, Wang Y, Chen W, Wang H.

Int J Mol Med. 2012 Jul;30(1):119-25. doi: 10.3892/ijmm.2012.955. Epub 2012 Apr 2.


Extract of Cassiae Semen and its major compound inhibit S100b-induced TGF-beta1 and fibronectin expression in mouse glomerular mesangial cells.

Jung DH, Kim YS, Kim NH, Lee J, Jang DS, Kim JS.

Eur J Pharmacol. 2010 Sep 1;641(1):7-14. doi: 10.1016/j.ejphar.2010.04.061. Epub 2010 May 17.


Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: involvement of NF-κB signaling pathway.

Jiang Q, Liu P, Wu X, Liu W, Shen X, Lan T, Xu S, Peng J, Xie X, Huang H.

Mol Cell Endocrinol. 2011 Jan 1;331(1):34-40. doi: 10.1016/j.mce.2010.07.023. Epub 2010 Jul 30.


[Effects of aldosterone on synthesis of fibronectin and expression of transforming growth factor-beta1 mRNA in cultured rat mesangial cells].

Li XD, Chen XW, Tang DS, Liang D, Liu HF.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2007 Feb;23(2):140-2. Chinese.


[Effect of nitrotyrosine on renal expressions of NF-κB, MCP-1 and TGF-β1 in rats with diabetic nephropathy].

Xu ZZ, Wang M, Wang YJ, Niu HX, Li XY, Zhou WD, Zhu Y, Long HB.

Nan Fang Yi Ke Da Xue Xue Bao. 2013 Mar;33(3):346-50. Chinese.


TGF-beta1 stimulates monocyte chemoattractant protein-1 expression in mesangial cells through a phosphodiesterase isoenzyme 4-dependent process.

Cheng J, Diaz Encarnacion MM, Warner GM, Gray CE, Nath KA, Grande JP.

Am J Physiol Cell Physiol. 2005 Oct;289(4):C959-70. Epub 2005 Jun 1.

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