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Items: 1 to 20 of 177

1.

The Vps35 D620N mutation linked to Parkinson's disease disrupts the cargo sorting function of retromer.

Follett J, Norwood SJ, Hamilton NA, Mohan M, Kovtun O, Tay S, Zhe Y, Wood SA, Mellick GD, Silburn PA, Collins BM, Bugarcic A, Teasdale RD.

Traffic. 2014 Feb;15(2):230-44. doi: 10.1111/tra.12136. Epub 2013 Nov 14.

2.

Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation.

McGough IJ, Steinberg F, Jia D, Barbuti PA, McMillan KJ, Heesom KJ, Whone AL, Caldwell MA, Billadeau DD, Rosen MK, Cullen PJ.

Curr Biol. 2014 Jul 21;24(14):1670-1676. doi: 10.1016/j.cub.2014.06.024. Epub 2014 Jul 3. Erratum in: Curr Biol. 2014 Jul 21;24(14):1678. Whone, Alan L [added].

3.

Retromer's Role in Endosomal Trafficking and Impaired Function in Neurodegenerative Diseases.

Follett J, Bugarcic A, Collins BM, Teasdale RD.

Curr Protein Pept Sci. 2017;18(7):687-701. doi: 10.2174/1389203717666160311121246. Review.

PMID:
26965691
4.

Vps26A and Vps26B subunits define distinct retromer complexes.

Bugarcic A, Zhe Y, Kerr MC, Griffin J, Collins BM, Teasdale RD.

Traffic. 2011 Dec;12(12):1759-73. doi: 10.1111/j.1600-0854.2011.01284.x. Epub 2011 Oct 17.

5.

VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease.

Miura E, Hasegawa T, Konno M, Suzuki M, Sugeno N, Fujikake N, Geisler S, Tabuchi M, Oshima R, Kikuchi A, Baba T, Wada K, Nagai Y, Takeda A, Aoki M.

Neurobiol Dis. 2014 Nov;71:1-13. doi: 10.1016/j.nbd.2014.07.014. Epub 2014 Aug 6.

PMID:
25107340
6.

Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N.

Munsie LN, Milnerwood AJ, Seibler P, Beccano-Kelly DA, Tatarnikov I, Khinda J, Volta M, Kadgien C, Cao LP, Tapia L, Klein C, Farrer MJ.

Hum Mol Genet. 2015 Mar 15;24(6):1691-703. doi: 10.1093/hmg/ddu582. Epub 2014 Nov 21.

PMID:
25416282
7.

Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy.

Zavodszky E, Seaman MN, Moreau K, Jimenez-Sanchez M, Breusegem SY, Harbour ME, Rubinsztein DC.

Nat Commun. 2014 May 13;5:3828. doi: 10.1038/ncomms4828.

8.

Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration.

Tsika E, Glauser L, Moser R, Fiser A, Daniel G, Sheerin UM, Lees A, Troncoso JC, Lewis PA, Bandopadhyay R, Schneider BL, Moore DJ.

Hum Mol Genet. 2014 Sep 1;23(17):4621-38. doi: 10.1093/hmg/ddu178. Epub 2014 Apr 15.

9.

VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process.

Fuse A, Furuya N, Kakuta S, Inose A, Sato M, Koike M, Saiki S, Hattori N.

FEBS Lett. 2015 Jun 4;589(13):1430-6. doi: 10.1016/j.febslet.2015.04.040. Epub 2015 May 1.

10.
11.

Implication of mouse Vps26b-Vps29-Vps35 retromer complex in sortilin trafficking.

Kim E, Lee Y, Lee HJ, Kim JS, Song BS, Huh JW, Lee SR, Kim SU, Kim SH, Hong Y, Shim I, Chang KT.

Biochem Biophys Res Commun. 2010 Dec 10;403(2):167-71. doi: 10.1016/j.bbrc.2010.10.121. Epub 2010 Oct 30.

PMID:
21040701
12.

Role of the VPS35 D620N mutation in Parkinson's disease.

Mohan M, Mellick GD.

Parkinsonism Relat Disord. 2017 Mar;36:10-18. doi: 10.1016/j.parkreldis.2016.12.001. Epub 2016 Dec 5. Review.

PMID:
27964832
13.

Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation.

Follett J, Bugarcic A, Yang Z, Ariotti N, Norwood SJ, Collins BM, Parton RG, Teasdale RD.

J Biol Chem. 2016 Aug 26;291(35):18283-98. doi: 10.1074/jbc.M115.703157. Epub 2016 Jul 6.

14.
15.

VPS35 pathogenic mutations confer no dominant toxicity but partial loss of function in Drosophila and genetically interact with parkin.

Malik BR, Godena VK, Whitworth AJ.

Hum Mol Genet. 2015 Nov 1;24(21):6106-17. doi: 10.1093/hmg/ddv322. Epub 2015 Aug 6.

16.

VPS35 mutation in Japanese patients with typical Parkinson's disease.

Ando M, Funayama M, Li Y, Kashihara K, Murakami Y, Ishizu N, Toyoda C, Noguchi K, Hashimoto T, Nakano N, Sasaki R, Kokubo Y, Kuzuhara S, Ogaki K, Yamashita C, Yoshino H, Hatano T, Tomiyama H, Hattori N.

Mov Disord. 2012 Sep 15;27(11):1413-7. doi: 10.1002/mds.25145. Epub 2012 Sep 18.

PMID:
22991136
17.

Vps26B-retromer negatively regulates plasma membrane resensitization of PAR-2.

Bugarcic A, Vetter I, Chalmers S, Kinna G, Collins BM, Teasdale RD.

Cell Biol Int. 2015 Nov;39(11):1299-306. doi: 10.1002/cbin.10508. Epub 2015 Jul 15.

PMID:
26113136
18.

A conserved retromer sorting motif is essential for mitochondrial DLP1 recycling by VPS35 in Parkinson's disease model.

Wang W, Ma X, Zhou L, Liu J, Zhu X.

Hum Mol Genet. 2017 Feb 15;26(4):781-789. doi: 10.1093/hmg/ddw430.

PMID:
28040727
19.

Endosomal recruitment of the WASH complex: active sequences and mutations impairing interaction with the retromer.

Helfer E, Harbour ME, Henriot V, Lakisic G, Sousa-Blin C, Volceanov L, Seaman MNJ, Gautreau A.

Biol Cell. 2013 May;105(5):191-207. doi: 10.1111/boc.201200038. Epub 2013 Mar 7.

PMID:
23331060
20.

Genetic variability of the retromer cargo recognition complex in parkinsonism.

Gustavsson EK, Guella I, Trinh J, Szu-Tu C, Rajput A, Rajput AH, Steele JC, McKeown M, Jeon BS, Aasly JO, Farrer MJ.

Mov Disord. 2015 Apr;30(4):580-4. doi: 10.1002/mds.26104. Epub 2014 Dec 5.

PMID:
25475142

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