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Items: 1 to 20 of 242

1.

Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models.

Shin JY, Park HJ, Kim HN, Oh SH, Bae JS, Ha HJ, Lee PH.

Autophagy. 2014 Jan;10(1):32-44. doi: 10.4161/auto.26508. Epub 2013 Jan 1.

2.

Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Neuronal Differentiation by Enhancing the Wnt Signaling Pathway in an Alzheimer's Disease Model.

Oh SH, Kim HN, Park HJ, Shin JY, Lee PH.

Cell Transplant. 2015;24(6):1097-109. doi: 10.3727/096368914X679237. Epub 2014 Mar 7.

PMID:
24612635
3.

Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis.

Guglielmotto M, Monteleone D, Piras A, Valsecchi V, Tropiano M, Ariano S, Fornaro M, Vercelli A, Puyal J, Arancio O, Tabaton M, Tamagno E.

Autophagy. 2014 Oct 1;10(10):1827-43. doi: 10.4161/auto.30001. Epub 2014 Aug 12.

4.

TFEB Participates in the Aβ-Induced Pathogenesis of Alzheimer's Disease by Regulating the Autophagy-Lysosome Pathway.

Zhang YD, Zhao JJ.

DNA Cell Biol. 2015 Nov;34(11):661-8. doi: 10.1089/dna.2014.2738. Epub 2015 Sep 14.

PMID:
26368054
5.

Neuroprotective effects of mesenchymal stem cells through autophagy modulation in a parkinsonian model.

Park HJ, Shin JY, Kim HN, Oh SH, Lee PH.

Neurobiol Aging. 2014 Aug;35(8):1920-8. doi: 10.1016/j.neurobiolaging.2014.01.028. Epub 2014 Jan 29.

PMID:
24629674
6.

Autophagy protects neuron from Abeta-induced cytotoxicity.

Hung SY, Huang WP, Liou HC, Fu WM.

Autophagy. 2009 May;5(4):502-10. Epub 2009 May 6.

PMID:
19270530
7.

Variations in the effects on synthesis of amyloid beta protein in modulated autophagic conditions.

Makioka K, Yamazaki T, Kakuda S, Okamoto K.

Neurol Res. 2009 Nov;31(9):959-68. doi: 10.1179/174313209X395463. Epub 2009 Feb 11.

PMID:
19215663
8.

Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice.

Wang C, Zhang X, Teng Z, Zhang T, Li Y.

Eur J Pharmacol. 2014 Oct 5;740:312-20. doi: 10.1016/j.ejphar.2014.06.051. Epub 2014 Jul 17.

PMID:
25041840
9.

Cilostazol Upregulates Autophagy via SIRT1 Activation: Reducing Amyloid-β Peptide and APP-CTFβ Levels in Neuronal Cells.

Lee HR, Shin HK, Park SY, Kim HY, Bae SS, Lee WS, Rhim BY, Hong KW, Kim CD.

PLoS One. 2015 Aug 5;10(8):e0134486. doi: 10.1371/journal.pone.0134486. eCollection 2015.

10.

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease.

Boland B, Kumar A, Lee S, Platt FM, Wegiel J, Yu WH, Nixon RA.

J Neurosci. 2008 Jul 2;28(27):6926-37. doi: 10.1523/JNEUROSCI.0800-08.2008.

11.

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.

Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, Wyss-Coray T.

J Clin Invest. 2008 Jun;118(6):2190-9. doi: 10.1172/JCI33585.

12.

Okadaic acid increases autophagosomes in rat neurons: implications for Alzheimer's disease.

Yoon SY, Choi JE, Kweon HS, Choe H, Kim SW, Hwang O, Lee H, Lee JY, Kim DH.

J Neurosci Res. 2008 Nov 1;86(14):3230-9. doi: 10.1002/jnr.21760.

PMID:
18615642
13.

Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction.

Xing S, Zhang Y, Li J, Zhang J, Li Y, Dang C, Li C, Fan Y, Yu J, Pei Z, Zeng J.

Autophagy. 2012 Jan;8(1):63-76. doi: 10.4161/auto.8.1.18217. Epub 2012 Jan 1.

PMID:
22108007
14.

Heat shock pretreatment improves stem cell repair following ischemia-reperfusion injury via autophagy.

Qiao PF, Yao L, Zhang XC, Li GD, Wu DQ.

World J Gastroenterol. 2015 Dec 7;21(45):12822-34. doi: 10.3748/wjg.v21.i45.12822.

15.

Temsirolimus promotes autophagic clearance of amyloid-β and provides protective effects in cellular and animal models of Alzheimer's disease.

Jiang T, Yu JT, Zhu XC, Tan MS, Wang HF, Cao L, Zhang QQ, Shi JQ, Gao L, Qin H, Zhang YD, Tan L.

Pharmacol Res. 2014 Mar;81:54-63. doi: 10.1016/j.phrs.2014.02.008. Epub 2014 Mar 3.

PMID:
24602800
16.

Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice.

Yang DS, Stavrides P, Kumar A, Jiang Y, Mohan PS, Ohno M, Dobrenis K, Davidson CD, Saito M, Pawlik M, Huo C, Walkley SU, Nixon RA.

Hum Mol Genet. 2017 Mar 1;26(5):843-859. doi: 10.1093/hmg/ddx001.

PMID:
28062666
17.

Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models.

Khandelwal PJ, Herman AM, Hoe HS, Rebeck GW, Moussa CE.

Hum Mol Genet. 2011 Jun 1;20(11):2091-102. doi: 10.1093/hmg/ddr091. Epub 2011 Mar 4.

18.

SUMO1 promotes Aβ production via the modulation of autophagy.

Cho SJ, Yun SM, Jo C, Lee DH, Choi KJ, Song JC, Park SI, Kim YJ, Koh YH.

Autophagy. 2015;11(1):100-12. doi: 10.4161/15548627.2014.984283.

19.

Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease.

Lonskaya I, Shekoyan AR, Hebron ML, Desforges N, Algarzae NK, Moussa CE.

J Alzheimers Dis. 2013;33(1):231-47. doi: 10.3233/JAD-2012-121141.

PMID:
22954671
20.

Moderate activation of autophagy regulates the intracellular calcium ion concentration and mitochondrial membrane potential in beta-amyloid-treated PC12 cells.

Xue Z, Guo Y, Fang Y.

Neurosci Lett. 2016 Apr 8;618:50-7. doi: 10.1016/j.neulet.2016.02.044. Epub 2016 Feb 26.

PMID:
26923671

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