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Items: 1 to 20 of 65

1.

Role of Rho/ROCK signaling in the interaction of melanoma cells with the blood-brain barrier.

Wilhelm I, Fazakas C, Molnár J, Haskó J, Végh AG, Cervenak L, Nagyőszi P, Nyúl-Tóth A, Farkas AE, Bauer H, Guillemin GJ, Bauer HC, Váró G, Krizbai IA.

Pigment Cell Melanoma Res. 2014 Jan;27(1):113-23. doi: 10.1111/pcmr.12169. Epub 2013 Oct 23.

PMID:
24148763
2.

Involvement of PI3K and ROCK signaling pathways in migration of bone marrow-derived mesenchymal stem cells through human brain microvascular endothelial cell monolayers.

Lin MN, Shang DS, Sun W, Li B, Xu X, Fang WG, Zhao WD, Cao L, Chen YH.

Brain Res. 2013 Jun 4;1513:1-8. doi: 10.1016/j.brainres.2013.03.035. Epub 2013 Mar 30.

PMID:
23548598
3.

Involvement of Rho/ROCK signalling in small cell lung cancer migration through human brain microvascular endothelial cells.

Li B, Zhao WD, Tan ZM, Fang WG, Zhu L, Chen YH.

FEBS Lett. 2006 Jul 24;580(17):4252-60. Epub 2006 Jun 30.

4.

Transmigration of melanoma cells through the blood-brain barrier: role of endothelial tight junctions and melanoma-released serine proteases.

Fazakas C, Wilhelm I, Nagyoszi P, Farkas AE, Haskó J, Molnár J, Bauer H, Bauer HC, Ayaydin F, Dung NT, Siklós L, Krizbai IA.

PLoS One. 2011;6(6):e20758. doi: 10.1371/journal.pone.0020758. Epub 2011 Jun 2.

5.

Evidence for involvement of ROCK signaling in bradykinin-induced increase in murine blood-tumor barrier permeability.

Ma T, Liu L, Wang P, Xue Y.

J Neurooncol. 2012 Jan;106(2):291-301. doi: 10.1007/s11060-011-0685-3. Epub 2011 Sep 3.

PMID:
21892742
6.

Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone.

Liu S, Goldstein RH, Scepansky EM, Rosenblatt M.

Cancer Res. 2009 Nov 15;69(22):8742-51. doi: 10.1158/0008-5472.CAN-09-1541. Epub 2009 Nov 3.

7.

CB2 receptor activation inhibits melanoma cell transmigration through the blood-brain barrier.

Haskó J, Fazakas C, Molnár J, Nyúl-Tóth Á, Herman H, Hermenean A, Wilhelm I, Persidsky Y, Krizbai IA.

Int J Mol Sci. 2014 May 8;15(5):8063-74. doi: 10.3390/ijms15058063.

8.

Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion.

Narumiya S, Tanji M, Ishizaki T.

Cancer Metastasis Rev. 2009 Jun;28(1-2):65-76. doi: 10.1007/s10555-008-9170-7. Review.

PMID:
19160018
9.

Rho kinase inhibitors block melanoma cell migration and inhibit metastasis.

Sadok A, McCarthy A, Caldwell J, Collins I, Garrett MD, Yeo M, Hooper S, Sahai E, Kuemper S, Mardakheh FK, Marshall CJ.

Cancer Res. 2015 Jun 1;75(11):2272-84. doi: 10.1158/0008-5472.CAN-14-2156. Epub 2015 Apr 3.

10.

Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin.

Niego B, Lee N, Larsson P, De Silva TM, Au AE, McCutcheon F, Medcalf RL.

PLoS One. 2017 May 16;12(5):e0177332. doi: 10.1371/journal.pone.0177332. eCollection 2017.

11.

The prostate transglutaminase (TGase-4, TGaseP) regulates the interaction of prostate cancer and vascular endothelial cells, a potential role for the ROCK pathway.

Jiang WG, Ablin RJ, Kynaston HG, Mason MD.

Microvasc Res. 2009 Mar;77(2):150-7. doi: 10.1016/j.mvr.2008.09.010. Epub 2008 Oct 15.

PMID:
18983858
12.

Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway.

Wang N, Zhang R, Wang SJ, Zhang CL, Mao LB, Zhuang CY, Tang YY, Luo XG, Zhou H, Zhang TC.

Int J Biochem Cell Biol. 2013 Jul;45(7):1447-56. doi: 10.1016/j.biocel.2013.04.021. Epub 2013 Apr 24.

PMID:
23624342
13.

Differing contributions of LIMK and ROCK to TGFβ-induced transcription, motility and invasion.

Morin P, Wickman G, Munro J, Inman GJ, Olson MF.

Eur J Cell Biol. 2011 Jan;90(1):13-25. doi: 10.1016/j.ejcb.2010.09.009. Epub 2010 Nov 11.

PMID:
21074289
14.

Pharmacological inhibition of Rho-kinase signaling with Y-27632 blocks melanoma tumor growth.

Routhier A, Astuccio M, Lahey D, Monfredo N, Johnson A, Callahan W, Partington A, Fellows K, Ouellette L, Zhidro S, Goodrow C, Smith A, Sullivan K, Simone P, Le L, Vezuli B, Zohni M, West E, Gleason D, Bryan B.

Oncol Rep. 2010 Mar;23(3):861-7.

PMID:
20127030
15.
16.

Novel anti-metastatic action of cidofovir mediated by inhibition of E6/E7, CXCR4 and Rho/ROCK signaling in HPV tumor cells.

Amine A, Rivera S, Opolon P, Dekkal M, Biard DS, Bouamar H, Louache F, McKay MJ, Bourhis J, Deutsch E, Vozenin-Brotons MC.

PLoS One. 2009;4(3):e5018. doi: 10.1371/journal.pone.0005018. Epub 2009 Mar 26.

17.

Stimulation of ectopic bone formation in response to BMP-2 by Rho kinase inhibitor: a pilot study.

Yoshikawa H, Yoshioka K, Nakase T, Itoh K.

Clin Orthop Relat Res. 2009 Dec;467(12):3087-95. doi: 10.1007/s11999-009-0976-6. Epub 2009 Jul 17.

18.

Arachidonic acid stimulates cell adhesion through a novel p38 MAPK-RhoA signaling pathway that involves heat shock protein 27.

Garcia MC, Ray DM, Lackford B, Rubino M, Olden K, Roberts JD.

J Biol Chem. 2009 Jul 31;284(31):20936-45. doi: 10.1074/jbc.M109.020271. Epub 2009 Jun 8.

19.

Phosphorylated caveolin-1 regulates Rho/ROCK-dependent focal adhesion dynamics and tumor cell migration and invasion.

Joshi B, Strugnell SS, Goetz JG, Kojic LD, Cox ME, Griffith OL, Chan SK, Jones SJ, Leung SP, Masoudi H, Leung S, Wiseman SM, Nabi IR.

Cancer Res. 2008 Oct 15;68(20):8210-20. doi: 10.1158/0008-5472.CAN-08-0343.

20.

ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells.

Joo HJ, Choi DK, Lim JS, Park JS, Lee SH, Song S, Shin JH, Lim DS, Kim I, Hwang KC, Koh GY.

Blood. 2012 Sep 27;120(13):2733-44. Epub 2012 Aug 14.

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