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Items: 1 to 20 of 96

1.

Metabolomics in drug discovery and development.

Robertson DG, Frevert U.

Clin Pharmacol Ther. 2013 Nov;94(5):559-61. doi: 10.1038/clpt.2013.120.

PMID:
24145714
2.

Applications of metabolomics in drug discovery and development.

Wishart DS.

Drugs R D. 2008;9(5):307-22. Review.

PMID:
18721000
3.

Potential of metabolomics in preclinical and clinical drug development.

Kumar B, Prakash A, Ruhela RK, Medhi B.

Pharmacol Rep. 2014 Dec;66(6):956-63. doi: 10.1016/j.pharep.2014.06.010. Epub 2014 Jun 24. Review.

PMID:
25443721
4.

Metabolomics and its potential in drug development.

Beyoğlu D, Idle JR.

Biochem Pharmacol. 2013 Jan 1;85(1):12-20. doi: 10.1016/j.bcp.2012.08.013. Epub 2012 Aug 23.

PMID:
22935449
5.

Metabolomics and its practical value in pharmaceutical industry.

Wei R.

Curr Drug Metab. 2011 May;12(4):345-58. Review.

PMID:
21395528
6.

Capillary electrophoresis-mass spectrometry in metabolomics: the potential for driving drug discovery and development.

Wang X, Li K, Adams E, Van Schepdael A.

Curr Drug Metab. 2013 Sep;14(7):807-13. Review.

PMID:
23937174
7.

The application of mass spectrometry to proteomics and metabolomics in biomarker discovery and drug development.

Mikami T, Aoki M, Kimura T.

Curr Mol Pharmacol. 2012 Jun;5(2):301-16. Review.

PMID:
22122469
8.

Metabolomics: moving to the clinic.

Nordström A, Lewensohn R.

J Neuroimmune Pharmacol. 2010 Mar;5(1):4-17. doi: 10.1007/s11481-009-9156-4. Epub 2009 Apr 28. Review.

PMID:
19399626
9.

Emerging applications of metabolomics in drug discovery and precision medicine.

Wishart DS.

Nat Rev Drug Discov. 2016 Jul;15(7):473-84. doi: 10.1038/nrd.2016.32. Epub 2016 Mar 11. Review.

PMID:
26965202
10.

Metabolomics for bioactivity assessment of natural products.

Yuliana ND, Khatib A, Choi YH, Verpoorte R.

Phytother Res. 2011 Feb;25(2):157-69. doi: 10.1002/ptr.3258. Review.

PMID:
20658470
11.

High-throughput screening, metabolomics and drug discovery.

Harrigan GG, Yates LA.

IDrugs. 2006 Mar;9(3):188-92.

PMID:
16523384
12.

Application of genomics, proteomics and metabolomics in drug discovery, development and clinic.

Russell C, Rahman A, Mohammed AR.

Ther Deliv. 2013 Mar;4(3):395-413. doi: 10.4155/tde.13.4. Review.

PMID:
23442083
13.

Biomarkers in Pharmaceutical Research.

Zhao X, Modur V, Carayannopoulos LN, Laterza OF.

Clin Chem. 2015 Nov;61(11):1343-53. doi: 10.1373/clinchem.2014.231712. Epub 2015 Sep 25. Review.

14.

Metabolomics in toxicology: preclinical and clinical applications.

Robertson DG, Watkins PB, Reily MD.

Toxicol Sci. 2011 Mar;120 Suppl 1:S146-70. doi: 10.1093/toxsci/kfq358. Epub 2010 Dec 2. Review. No abstract available.

PMID:
21127352
15.

From biomarker strategies to biomarker activities and back.

van Gool AJ, Henry B, Sprengers ED.

Drug Discov Today. 2010 Feb;15(3-4):121-6. doi: 10.1016/j.drudis.2009.11.004. Epub 2009 Nov 18. Review.

PMID:
19931413
16.

Systems drug discovery: a quantitative, objective approach for safer drug development.

Bickle M.

Expert Opin Drug Discov. 2012 Sep;7(9):757-9. doi: 10.1517/17460441.2012.710197. Epub 2012 Jul 25.

PMID:
22827715
17.

Metabolomics in pharmaceutical research and development: metabolites, mechanisms and pathways.

Xu EY, Schaefer WH, Xu Q.

Curr Opin Drug Discov Devel. 2009 Jan;12(1):40-52. Review.

PMID:
19152212
18.

Improved preclinical safety assessment using micro-BAL devices: the potential impact on human discovery and drug attrition.

Giri S, Bader A.

Drug Discov Today. 2011 May;16(9-10):382-97. doi: 10.1016/j.drudis.2011.02.012. Epub 2011 Feb 24. Review.

PMID:
21354326
19.

Structure-directed combinatorial library design.

Zhou JZ.

Curr Opin Chem Biol. 2008 Jun;12(3):379-85. doi: 10.1016/j.cbpa.2008.02.007. Epub 2008 Mar 20. Review.

PMID:
18328830
20.

De-risking drug discovery with ADDME -- avoiding drug development mistakes early.

Tsaioun K, Jacewicz M.

Altern Lab Anim. 2009 Sep;37 Suppl 1:47-55. Review.

PMID:
19807206

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