Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 89

1.

SIRT5 desuccinylates and activates SOD1 to eliminate ROS.

Lin ZF, Xu HB, Wang JY, Lin Q, Ruan Z, Liu FB, Jin W, Huang HH, Chen X.

Biochem Biophys Res Commun. 2013 Nov 8;441(1):191-5. doi: 10.1016/j.bbrc.2013.10.033. Epub 2013 Oct 16.

PMID:
24140062
2.

Desuccinylation of pyruvate kinase M2 by SIRT5 contributes to antioxidant response and tumor growth.

Xiangyun Y, Xiaomin N, Linping G, Yunhua X, Ziming L, Yongfeng Y, Zhiwei C, Shun L.

Oncotarget. 2017 Jan 24;8(4):6984-6993. doi: 10.18632/oncotarget.14346.

3.

SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense.

Zhou L, Wang F, Sun R, Chen X, Zhang M, Xu Q, Wang Y, Wang S, Xiong Y, Guan KL, Yang P, Yu H, Ye D.

EMBO Rep. 2016 Jun;17(6):811-22. doi: 10.15252/embr.201541643. Epub 2016 Apr 9.

4.

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS.

Chen Y, Zhang J, Lin Y, Lei Q, Guan KL, Zhao S, Xiong Y.

EMBO Rep. 2011 Jun;12(6):534-41. doi: 10.1038/embor.2011.65. Epub 2011 May 13.

5.

SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.

Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, Mulhern D, Stevens RD, Ilkayeva OR, Newgard CB, Jacobson MP, Hellerstein M, Goetzman ES, Gibson BW, Verdin E.

Cell Metab. 2013 Dec 3;18(6):920-33. doi: 10.1016/j.cmet.2013.11.013.

6.

Quantitative Analysis of the Sirt5-Regulated Lysine Succinylation Proteome in Mammalian Cells.

Chen Y.

Methods Mol Biol. 2016;1410:23-37. doi: 10.1007/978-1-4939-3524-6_2.

PMID:
26867736
7.

SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase.

Zhang Y, Bharathi SS, Rardin MJ, Uppala R, Verdin E, Gibson BW, Goetzman ES.

PLoS One. 2015 Mar 26;10(3):e0122297. doi: 10.1371/journal.pone.0122297. eCollection 2015.

8.

Different regulation of wild-type and mutant Cu,Zn superoxide dismutase localization in mammalian mitochondria.

Kawamata H, Manfredi G.

Hum Mol Genet. 2008 Nov 1;17(21):3303-17. doi: 10.1093/hmg/ddn226. Epub 2008 Aug 13.

9.

Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity.

Li Q, Spencer NY, Pantazis NJ, Engelhardt JF.

J Biol Chem. 2011 Nov 18;286(46):40151-62. doi: 10.1074/jbc.M111.279711. Epub 2011 Sep 20.

10.

Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.

Sadhukhan S, Liu X, Ryu D, Nelson OD, Stupinski JA, Li Z, Chen W, Zhang S, Weiss RS, Locasale JW, Auwerx J, Lin H.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4320-5. doi: 10.1073/pnas.1519858113. Epub 2016 Apr 5.

11.

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.

Mol Cell. 2013 Jun 27;50(6):919-30. doi: 10.1016/j.molcel.2013.06.001.

12.

Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage.

Auclair JR, Johnson JL, Liu Q, Salisbury JP, Rotunno MS, Petsko GA, Ringe D, Brown RH Jr, Bosco DA, Agar JN.

Biochemistry. 2013 Sep 10;52(36):6137-44. doi: 10.1021/bi4006122. Epub 2013 Aug 26.

13.

Deleterious role of superoxide dismutase in the mitochondrial intermembrane space.

Goldsteins G, Keksa-Goldsteine V, Ahtoniemi T, Jaronen M, Arens E, Akerman K, Chan PH, Koistinaho J.

J Biol Chem. 2008 Mar 28;283(13):8446-52. doi: 10.1074/jbc.M706111200. Epub 2008 Jan 2.

14.
15.

Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents.

Lin C, Zeng H, Lu J, Xie Z, Sun W, Luo C, Ding J, Yuan S, Geng M, Huang M.

Oncotarget. 2015 Aug 21;6(24):20578-91.

16.

Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain.

Zhang Y, Bharathi SS, Rardin MJ, Lu J, Maringer KV, Sims-Lucas S, Prochownik EV, Gibson BW, Goetzman ES.

J Biol Chem. 2017 Jun 16;292(24):10239-10249. doi: 10.1074/jbc.M117.785022. Epub 2017 Apr 30.

PMID:
28458255
17.

Mutant SOD1 from spinal cord of G93A rats is destabilized and binds to inner mitochondrial membrane.

Ahtoniemi T, Jaronen M, Keksa-Goldsteine V, Goldsteins G, Koistinaho J.

Neurobiol Dis. 2008 Dec;32(3):479-85. doi: 10.1016/j.nbd.2008.08.010. Epub 2008 Sep 9.

PMID:
18817872
18.
19.

Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling.

Juarez JC, Manuia M, Burnett ME, Betancourt O, Boivin B, Shaw DE, Tonks NK, Mazar AP, DoƱate F.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7147-52. doi: 10.1073/pnas.0709451105. Epub 2008 May 14.

20.

The first identification of lysine malonylation substrates and its regulatory enzyme.

Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, Dai J, Verdin E, Ye Y, Zhao Y.

Mol Cell Proteomics. 2011 Dec;10(12):M111.012658. doi: 10.1074/mcp.M111.012658. Epub 2011 Sep 9.

Supplemental Content

Support Center