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Items: 1 to 20 of 228

1.

A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections.

Kosaka K, Hiraga N, Imamura M, Yoshimi S, Murakami E, Nakahara T, Honda Y, Ono A, Kawaoka T, Tsuge M, Abe H, Hayes CN, Miki D, Aikata H, Ochi H, Ishida Y, Tateno C, Yoshizato K, Sasaki T, Chayama K.

Biochem Biophys Res Commun. 2013 Nov 8;441(1):230-5. doi: 10.1016/j.bbrc.2013.10.040. Epub 2013 Oct 16.

PMID:
24140055
2.

Chimeric mouse model for the infection of hepatitis B and C viruses.

Tesfaye A, Stift J, Maric D, Cui Q, Dienes HP, Feinstone SM.

PLoS One. 2013 Oct 14;8(10):e77298. doi: 10.1371/journal.pone.0077298. eCollection 2013.

3.

Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice.

Vanwolleghem T, Libbrecht L, Hansen BE, Desombere I, Roskams T, Meuleman P, Leroux-Roels G.

J Hepatol. 2010 Sep;53(3):468-76. doi: 10.1016/j.jhep.2010.03.024. Epub 2010 May 31.

PMID:
20591528
4.

The human liver-uPA-SCID mouse: a model for the evaluation of antiviral compounds against HBV and HCV.

Meuleman P, Leroux-Roels G.

Antiviral Res. 2008 Dec;80(3):231-8. doi: 10.1016/j.antiviral.2008.07.006. Epub 2008 Aug 14. Review.

PMID:
18706933
5.

Therapeutic efficacy of human hepatocyte transplantation in a SCID/uPA mouse model with inducible liver disease.

Douglas DN, Kawahara T, Sis B, Bond D, Fischer KP, Tyrrell DL, Lewis JT, Kneteman NM.

PLoS One. 2010 Feb 18;5(2):e9209. doi: 10.1371/journal.pone.0009209.

6.

Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology.

Uchida T, Imamura M, Kan H, Hiraga N, Hayes CN, Tsuge M, Abe-Chayama H, Aikata H, Makokha GN, Miki D, Ochi H, Ishida Y, Tateno C, Chayama K.

J Gen Virol. 2017 May;98(5):1040-1047. doi: 10.1099/jgv.0.000726. Epub 2017 May 25.

PMID:
28141486
7.

Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse.

Vanwolleghem T, Meuleman P, Libbrecht L, Roskams T, De Vos R, Leroux-Roels G.

Gastroenterology. 2007 Oct;133(4):1144-55. Epub 2007 Jul 10.

PMID:
17919490
8.

Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.

LĆ¼tgehetmann M, Mancke LV, Volz T, Helbig M, Allweiss L, Bornscheuer T, Pollok JM, Lohse AW, Petersen J, Urban S, Dandri M.

Hepatology. 2012 Mar;55(3):685-94. doi: 10.1002/hep.24758. Epub 2012 Jan 30.

PMID:
22031488
9.

Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera.

Meuleman P, Libbrecht L, De Vos R, de Hemptinne B, Gevaert K, Vandekerckhove J, Roskams T, Leroux-Roels G.

Hepatology. 2005 Apr;41(4):847-56.

PMID:
15791625
10.

Animal model for study of human hepatitis viruses.

Chayama K, Hayes CN, Hiraga N, Abe H, Tsuge M, Imamura M.

J Gastroenterol Hepatol. 2011 Jan;26(1):13-8. doi: 10.1111/j.1440-1746.2010.06470.x. Review.

PMID:
21175788
11.

Human hepatocytes secrete soluble CD14, a process not directly influenced by HBV and HCV infection.

Meuleman P, Steyaert S, Libbrecht L, Couvent S, Van Houtte F, Clinckspoor F, de Hemptinne B, Roskams T, Vanlandschoot P, Leroux-Roels G.

Clin Chim Acta. 2006 Apr;366(1-2):156-62. Epub 2005 Oct 25.

PMID:
16253217
12.

Generation of humanized liver mouse model by transplant of patient-derived fresh human hepatocytes.

Kim M, Choi B, Joo SY, Lee H, Lee JH, Lee KW, Lee S, Park JB, Lee SK, Kim SJ.

Transplant Proc. 2014 May;46(4):1186-90. doi: 10.1016/j.transproceed.2013.11.098.

PMID:
24815156
13.

Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice.

Uchida T, Hiraga N, Imamura M, Tsuge M, Abe H, Hayes CN, Aikata H, Ishida Y, Tateno C, Yoshizato K, Ohdan H, Murakami K, Chayama K.

J Virol. 2015 Oct;89(19):10087-96. doi: 10.1128/JVI.01126-15. Epub 2015 Aug 5.

14.

Neutralizing antibodies induced by cell culture-derived hepatitis C virus protect against infection in mice.

Akazawa D, Moriyama M, Yokokawa H, Omi N, Watanabe N, Date T, Morikawa K, Aizaki H, Ishii K, Kato T, Mochizuki H, Nakamura N, Wakita T.

Gastroenterology. 2013 Aug;145(2):447-55.e1-4. doi: 10.1053/j.gastro.2013.05.007. Epub 2013 May 11.

PMID:
23673355
15.

Development of humanized mice for the study of hepatitis C virus infection.

Turrini P, Sasso R, Germoni S, Marcucci I, Celluci A, Di Marco A, Marra E, Paonessa G, Eutropi A, Laufer R, Migliaccio G, Padron J.

Transplant Proc. 2006 May;38(4):1181-4.

PMID:
16757300
16.

Direct cytopathic effects of particular hepatitis B virus genotypes in severe combined immunodeficiency transgenic with urokinase-type plasminogen activator mouse with human hepatocytes.

Sugiyama M, Tanaka Y, Kurbanov F, Maruyama I, Shimada T, Takahashi S, Shirai T, Hino K, Sakaida I, Mizokami M.

Gastroenterology. 2009 Feb;136(2):652-62.e3. doi: 10.1053/j.gastro.2008.10.048. Epub 2008 Oct 29.

PMID:
19041311
17.

Hepatitis virus infection affects DNA methylation in mice with humanized livers.

Okamoto Y, Shinjo K, Shimizu Y, Sano T, Yamao K, Gao W, Fujii M, Osada H, Sekido Y, Murakami S, Tanaka Y, Joh T, Sato S, Takahashi S, Wakita T, Zhu J, Issa JP, Kondo Y.

Gastroenterology. 2014 Feb;146(2):562-72. doi: 10.1053/j.gastro.2013.10.056. Epub 2013 Oct 30.

PMID:
24184133
18.

Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice.

Suemizu H, Hasegawa M, Kawai K, Taniguchi K, Monnai M, Wakui M, Suematsu M, Ito M, Peltz G, Nakamura M.

Biochem Biophys Res Commun. 2008 Dec 5;377(1):248-52. doi: 10.1016/j.bbrc.2008.09.124. Epub 2008 Oct 7.

PMID:
18840406
19.

Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor.

Kamiya N, Iwao E, Hiraga N, Tsuge M, Imamura M, Takahashi S, Miyoshi S, Tateno C, Yoshizato K, Chayama K.

J Gen Virol. 2010 Jul;91(Pt 7):1668-77. doi: 10.1099/vir.0.019315-0. Epub 2010 Feb 17.

PMID:
20164258
20.

Antiviral activity of Bay 41-4109 on hepatitis B virus in humanized Alb-uPA/SCID mice.

Brezillon N, Brunelle MN, Massinet H, Giang E, Lamant C, DaSilva L, Berissi S, Belghiti J, Hannoun L, Puerstinger G, Wimmer E, Neyts J, Hantz O, Soussan P, Morosan S, Kremsdorf D.

PLoS One. 2011;6(12):e25096. doi: 10.1371/journal.pone.0025096. Epub 2011 Dec 5.

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