Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 153


Transcriptional responses of neonatal mouse lung to hyperoxia by Nrf2 status.

McGrath-Morrow SA, Lauer T, Collaco JM, Lopez A, Malhotra D, Alekseyev YO, Neptune E, Wise R, Biswal S.

Cytokine. 2014 Jan;65(1):4-9. doi: 10.1016/j.cyto.2013.09.021. Epub 2013 Oct 17.


Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia.

McGrath-Morrow S, Lauer T, Yee M, Neptune E, Podowski M, Thimmulappa RK, O'Reilly M, Biswal S.

Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L565-73. doi: 10.1152/ajplung.90487.2008. Epub 2009 Jan 16.


Targeted deletion of nrf2 impairs lung development and oxidant injury in neonatal mice.

Cho HY, van Houten B, Wang X, Miller-DeGraff L, Fostel J, Gladwell W, Perrow L, Panduri V, Kobzik L, Yamamoto M, Bell DA, Kleeberger SR.

Antioxid Redox Signal. 2012 Oct 15;17(8):1066-82. doi: 10.1089/ars.2011.4288. Epub 2012 Apr 18.


Thioredoxin Reductase Inhibition Attenuates Neonatal Hyperoxic Lung Injury and Enhances Nuclear Factor E2-Related Factor 2 Activation.

Li Q, Wall SB, Ren C, Velten M, Hill CL, Locy ML, Rogers LK, Tipple TE.

Am J Respir Cell Mol Biol. 2016 Sep;55(3):419-28. doi: 10.1165/rcmb.2015-0228OC.


[Apoptosis in neonatal rat lung exposed to hyperoxia].

Li YX, Luo XP, Liao LJ, Liu WJ, Ning Q.

Zhonghua Er Ke Za Zhi. 2005 Aug;43(8):585-90. Chinese.


The effect of neonatal hyperoxia on the lung of p21Waf1/Cip1/Sdi1-deficient mice.

McGrath-Morrow SA, Cho C, Soutiere S, Mitzner W, Tuder R.

Am J Respir Cell Mol Biol. 2004 May;30(5):635-40. Epub 2003 Nov 7.


Superoxide dismutase 3 dysregulation in a murine model of neonatal lung injury.

Poonyagariyagorn HK, Metzger S, Dikeman D, Mercado AL, Malinina A, Calvi C, McGrath-Morrow S, Neptune ER.

Am J Respir Cell Mol Biol. 2014 Sep;51(3):380-90. doi: 10.1165/rcmb.2013-0043OC.


Hyperoxia impairs alveolar formation and induces senescence through decreased histone deacetylase activity and up-regulation of p21 in neonatal mouse lung.

Londhe VA, Sundar IK, Lopez B, Maisonet TM, Yu Y, Aghai ZH, Rahman I.

Pediatr Res. 2011 May;69(5 Pt 1):371-7. doi: 10.1203/PDR.0b013e318211c917.


PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice.

Reddy NM, Potteti HR, Vegiraju S, Chen HJ, Tamatam CM, Reddy SP.

PLoS One. 2015 Jun 15;10(6):e0129676. doi: 10.1371/journal.pone.0129676. eCollection 2015.


The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette smoke-induced emphysematous changes.

Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schüller J, Xu H, Taguchi K, Yamamoto M, Müller T.

Toxicol Sci. 2010 May;115(1):238-52. doi: 10.1093/toxsci/kfq039. Epub 2010 Feb 4.


Sustained hyperoxia-induced NF-κB activation improves survival and preserves lung development in neonatal mice.

McKenna S, Michaelis KA, Agboke F, Liu T, Han K, Yang G, Dennery PA, Wright CJ.

Am J Physiol Lung Cell Mol Physiol. 2014 Jun 15;306(12):L1078-89. doi: 10.1152/ajplung.00001.2014. Epub 2014 Apr 18.


Gene expression profiling of NRF2-mediated protection against oxidative injury.

Cho HY, Reddy SP, Debiase A, Yamamoto M, Kleeberger SR.

Free Radic Biol Med. 2005 Feb 1;38(3):325-43.


Sirtuin 1 Promotes Hyperoxia-Induced Lung Epithelial Cell Death Independent of NF-E2-Related Factor 2 Activation.

Potteti HR, Rajasekaran S, Rajamohan SB, Tamatam CR, Reddy NM, Reddy SP.

Am J Respir Cell Mol Biol. 2016 May;54(5):697-706. doi: 10.1165/rcmb.2014-0056OC.


The genome-wide transcriptional response to neonatal hyperoxia identifies Ahr as a key regulator.

Bhattacharya S, Zhou Z, Yee M, Chu CY, Lopez AM, Lunger VA, Solleti SK, Resseguie E, Buczynski B, Mariani TJ, O'Reilly MA.

Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1;307(7):L516-23. doi: 10.1152/ajplung.00200.2014. Epub 2014 Aug 22.


Comparison of adult and newborn pulmonary cytokine mRNA expression after hyperoxia.

Johnston CJ, Wright TW, Reed CK, Finkelstein JN.

Exp Lung Res. 1997 Nov-Dec;23(6):537-52.


[Protective Effect of Activated Nrf2 against Hyperoxia-induced Lung Injury in Neonatal Rats].

Ni J, Lin YG, Wu L, Huang W, Wei JF, Jiang XQ.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2015 May;46(3):399-402. Chinese.


Hyperoxia stimulates an Nrf2-ARE transcriptional response via ROS-EGFR-PI3K-Akt/ERK MAP kinase signaling in pulmonary epithelial cells.

Papaiahgari S, Zhang Q, Kleeberger SR, Cho HY, Reddy SP.

Antioxid Redox Signal. 2006 Jan-Feb;8(1-2):43-52.


The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis.

Pekovic-Vaughan V, Gibbs J, Yoshitane H, Yang N, Pathiranage D, Guo B, Sagami A, Taguchi K, Bechtold D, Loudon A, Yamamoto M, Chan J, van der Horst GT, Fukada Y, Meng QJ.

Genes Dev. 2014 Mar 15;28(6):548-60. doi: 10.1101/gad.237081.113.


Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice.

Reddy NM, Suryanarayana V, Kalvakolanu DV, Yamamoto M, Kensler TW, Hassoun PM, Kleeberger SR, Reddy SP.

J Immunol. 2009 Oct 1;183(7):4601-8. doi: 10.4049/jimmunol.0901754. Epub 2009 Sep 4.

Supplemental Content

Support Center