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Items: 1 to 20 of 119

1.

PTP1B is an effector of activin signaling and regulates neural specification of embryonic stem cells.

Matulka K, Lin HH, Hříbková H, Uwanogho D, Dvořák P, Sun YM.

Cell Stem Cell. 2013 Dec 5;13(6):706-19. doi: 10.1016/j.stem.2013.09.016. Epub 2013 Oct 17.

2.

Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions.

Lee KL, Lim SK, Orlov YL, Yit le Y, Yang H, Ang LT, Poellinger L, Lim B.

PLoS Genet. 2011 Jun;7(6):e1002130. doi: 10.1371/journal.pgen.1002130. Epub 2011 Jun 23.

3.

Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling.

Sumi T, Tsuneyoshi N, Nakatsuji N, Suemori H.

Development. 2008 Sep;135(17):2969-79. doi: 10.1242/dev.021121. Epub 2008 Jul 30.

4.

BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway.

Stewart A, Guan H, Yang K.

J Cell Physiol. 2010 Jun;223(3):658-66. doi: 10.1002/jcp.22064.

PMID:
20143330
5.

Smad2 mediates Activin/Nodal signaling in mesendoderm differentiation of mouse embryonic stem cells.

Fei T, Zhu S, Xia K, Zhang J, Li Z, Han JD, Chen YG.

Cell Res. 2010 Dec;20(12):1306-18. doi: 10.1038/cr.2010.158. Epub 2010 Nov 16.

PMID:
21079647
6.

FGF inhibition directs BMP4-mediated differentiation of human embryonic stem cells to syncytiotrophoblast.

Sudheer S, Bhushan R, Fauler B, Lehrach H, Adjaye J.

Stem Cells Dev. 2012 Nov 1;21(16):2987-3000. doi: 10.1089/scd.2012.0099. Epub 2012 Aug 6.

7.

SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.

Chng Z, Teo A, Pedersen RA, Vallier L.

Cell Stem Cell. 2010 Jan 8;6(1):59-70. doi: 10.1016/j.stem.2009.11.015.

8.

The generation of definitive endoderm from human embryonic stem cells is initially independent from activin A but requires canonical Wnt-signaling.

Naujok O, Diekmann U, Lenzen S.

Stem Cell Rev. 2014 Aug;10(4):480-93. doi: 10.1007/s12015-014-9509-0.

PMID:
24913278
9.

Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells.

Vallier L, Alexander M, Pedersen RA.

J Cell Sci. 2005 Oct 1;118(Pt 19):4495-509.

10.

Identification of a novel negative regulator of activin/nodal signaling in mesendodermal formation of Xenopus embryos.

Cheong SM, Kim H, Han JK.

J Biol Chem. 2009 Jun 19;284(25):17052-60. doi: 10.1074/jbc.M109.007443. Epub 2009 Apr 22.

11.

Inhibition of ERK1/2 prevents neural and mesendodermal differentiation and promotes human embryonic stem cell self-renewal.

Na J, Furue MK, Andrews PW.

Stem Cell Res. 2010 Sep;5(2):157-69. doi: 10.1016/j.scr.2010.06.002. Epub 2010 Aug 3.

12.

Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage.

Ji AR, Ku SY, Cho MS, Kim YY, Kim YJ, Oh SK, Kim SH, Moon SY, Choi YM.

Exp Mol Med. 2010 Mar 31;42(3):175-86.

13.

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells.

James D, Levine AJ, Besser D, Hemmati-Brivanlou A.

Development. 2005 Mar;132(6):1273-82. Epub 2005 Feb 9.

14.

Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm.

Smith JR, Vallier L, Lupo G, Alexander M, Harris WA, Pedersen RA.

Dev Biol. 2008 Jan 1;313(1):107-17. Epub 2007 Oct 11.

15.

Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.

Patani R, Compston A, Puddifoot CA, Wyllie DJ, Hardingham GE, Allen ND, Chandran S.

PLoS One. 2009 Oct 6;4(10):e7327. doi: 10.1371/journal.pone.0007327.

16.

Enhanced differentiation of human embryonic stem cells to mesenchymal progenitors by inhibition of TGF-beta/activin/nodal signaling using SB-431542.

Mahmood A, Harkness L, Schrøder HD, Abdallah BM, Kassem M.

J Bone Miner Res. 2010 Jun;25(6):1216-33. doi: 10.1002/jbmr.34.

17.

Patterning of mouse embryonic stem cell-derived pan-mesoderm by Activin A/Nodal and Bmp4 signaling requires Fibroblast Growth Factor activity.

Willems E, Leyns L.

Differentiation. 2008 Sep;76(7):745-59. doi: 10.1111/j.1432-0436.2007.00257.x. Epub 2008 Jan 3.

PMID:
18177426
18.

Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential.

Duggal G, Heindryckx B, Warrier S, O'Leary T, Van der Jeught M, Lierman S, Vossaert L, Deroo T, Deforce D, Chuva de Sousa Lopes SM, De Sutter P.

Stem Cells Dev. 2013 Dec 1;22(23):3141-55. doi: 10.1089/scd.2013.0024. Epub 2013 Aug 14.

19.

Induction of primordial germ cell-like cells from mouse embryonic stem cells by ERK signal inhibition.

Kimura T, Kaga Y, Ohta H, Odamoto M, Sekita Y, Li K, Yamano N, Fujikawa K, Isotani A, Sasaki N, Toyoda M, Hayashi K, Okabe M, Shinohara T, Saitou M, Nakano T.

Stem Cells. 2014 Oct;32(10):2668-78. doi: 10.1002/stem.1781.

20.

Transcription elongation factor Tcea3 regulates the pluripotent differentiation potential of mouse embryonic stem cells via the Lefty1-Nodal-Smad2 pathway.

Park KS, Cha Y, Kim CH, Ahn HJ, Kim D, Ko S, Kim KH, Chang MY, Ko JH, Noh YS, Han YM, Kim J, Song J, Kim JY, Tesar PJ, Lanza R, Lee KA, Kim KS.

Stem Cells. 2013 Feb;31(2):282-92. doi: 10.1002/stem.1284.

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