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Items: 1 to 20 of 137

1.

Scn8a voltage-gated sodium channel mutation alters seizure and anxiety responses to acute stress.

Sawyer NT, Papale LA, Eliason J, Neigh GN, Escayg A.

Psychoneuroendocrinology. 2014 Jan;39:225-36. doi: 10.1016/j.psyneuen.2013.09.018. Epub 2013 Sep 24.

2.

Scn1a dysfunction alters behavior but not the effect of stress on seizure response.

Sawyer NT, Helvig AW, Makinson CD, Decker MJ, Neigh GN, Escayg A.

Genes Brain Behav. 2016 Mar;15(3):335-47. doi: 10.1111/gbb.12281. Epub 2016 Jan 21.

PMID:
26694226
3.

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

Makinson CD, Dutt K, Lin F, Papale LA, Shankar A, Barela AJ, Liu R, Goldin AL, Escayg A.

Exp Neurol. 2016 Jan;275 Pt 1:46-58. doi: 10.1016/j.expneurol.2015.09.008. Epub 2015 Sep 26.

4.

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

Makinson CD, Tanaka BS, Lamar T, Goldin AL, Escayg A.

Neurobiol Dis. 2014 Aug;68:16-25. doi: 10.1016/j.nbd.2014.03.014. Epub 2014 Apr 2.

5.

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

Martin MS, Tang B, Papale LA, Yu FH, Catterall WA, Escayg A.

Hum Mol Genet. 2007 Dec 1;16(23):2892-9. Epub 2007 Sep 19.

PMID:
17881658
6.

Convulsive seizures and SUDEP in a mouse model of SCN8A epileptic encephalopathy.

Wagnon JL, Korn MJ, Parent R, Tarpey TA, Jones JM, Hammer MF, Murphy GG, Parent JM, Meisler MH.

Hum Mol Genet. 2015 Jan 15;24(2):506-15. doi: 10.1093/hmg/ddu470. Epub 2014 Sep 16.

7.

Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of SCN8A Encephalopathy.

Ottolini M, Barker BS, Gaykema RP, Meisler MH, Patel MK.

J Neurosci. 2017 Aug 9;37(32):7643-7655. doi: 10.1523/JNEUROSCI.2709-16.2017. Epub 2017 Jul 4.

PMID:
28676574
8.

Dysfunction of the Scn8a voltage-gated sodium channel alters sleep architecture, reduces diurnal corticosterone levels, and enhances spatial memory.

Papale LA, Paul KN, Sawyer NT, Manns JR, Tufik S, Escayg A.

J Biol Chem. 2010 May 28;285(22):16553-61. doi: 10.1074/jbc.M109.090084. Epub 2010 Mar 30.

9.

Regulation of Thalamic and Cortical Network Synchrony by Scn8a.

Makinson CD, Tanaka BS, Sorokin JM, Wong JC, Christian CA, Goldin AL, Escayg A, Huguenard JR.

Neuron. 2017 Mar 8;93(5):1165-1179.e6. doi: 10.1016/j.neuron.2017.01.031. Epub 2017 Feb 23.

PMID:
28238546
10.

Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy.

Oliva MK, McGarr TC, Beyer BJ, Gazina E, Kaplan DI, Cordeiro L, Thomas E, Dib-Hajj SD, Waxman SG, Frankel WN, Petrou S.

Neurobiol Dis. 2014 Jul;67:180-90. doi: 10.1016/j.nbd.2014.03.007. Epub 2014 Mar 19.

11.

Electroclinical features of epileptic encephalopathy caused by SCN8A mutation.

Takahashi S, Yamamoto S, Okayama A, Araki A, Saitsu H, Matsumoto N, Azuma H.

Pediatr Int. 2015 Aug;57(4):758-62. doi: 10.1111/ped.12622. Epub 2015 May 6.

PMID:
25951352
12.

An unexpected increase in restraint duration alters the expression of stress response habituation.

Kearns RR, Spencer RL.

Physiol Behav. 2013 Oct 2;122:193-200. doi: 10.1016/j.physbeh.2013.03.029. Epub 2013 Apr 6.

13.

The phenotypic spectrum of SCN8A encephalopathy.

Larsen J, Carvill GL, Gardella E, Kluger G, Schmiedel G, Barisic N, Depienne C, Brilstra E, Mang Y, Nielsen JE, Kirkpatrick M, Goudie D, Goldman R, Jähn JA, Jepsen B, Gill D, Döcker M, Biskup S, McMahon JM, Koeleman B, Harris M, Braun K, de Kovel CG, Marini C, Specchio N, Djémié T, Weckhuysen S, Tommerup N, Troncoso M, Troncoso L, Bevot A, Wolff M, Hjalgrim H, Guerrini R, Scheffer IE, Mefford HC, Møller RS; EuroEPINOMICS RES Consortium CRP.

Neurology. 2015 Feb 3;84(5):480-9. doi: 10.1212/WNL.0000000000001211. Epub 2015 Jan 7.

14.

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

Hawkins NA, Martin MS, Frankel WN, Kearney JA, Escayg A.

Neurobiol Dis. 2011 Mar;41(3):655-60. doi: 10.1016/j.nbd.2010.11.016. Epub 2010 Dec 13.

15.

Prenatal stress programs neuroendocrine stress responses and affective behaviors in second generation rats in a sex-dependent manner.

Grundwald NJ, Brunton PJ.

Psychoneuroendocrinology. 2015 Dec;62:204-16. doi: 10.1016/j.psyneuen.2015.08.010. Epub 2015 Aug 17.

16.

Remarkable Phenytoin Sensitivity in 4 Children with SCN8A-related Epilepsy: A Molecular Neuropharmacological Approach.

Boerma RS, Braun KP, van den Broek MP, van Berkestijn FM, Swinkels ME, Hagebeuk EO, Lindhout D, van Kempen M, Boon M, Nicolai J, de Kovel CG, Brilstra EH, Koeleman BP.

Neurotherapeutics. 2016 Jan;13(1):192-7. doi: 10.1007/s13311-015-0372-8. Erratum in: Neurotherapeutics. 2016 Jan;13(1):238. van de Broek, Maarten P H [Corrected to van den Broek, Marcel P H].

17.

Behavioral and neuroendocrine consequences of juvenile stress combined with adult immobilization in male rats.

Fuentes S, Carrasco J, Armario A, Nadal R.

Horm Behav. 2014 Aug;66(3):475-86. doi: 10.1016/j.yhbeh.2014.07.003. Epub 2014 Jul 15.

PMID:
25036868
18.

Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice.

Papale LA, Beyer B, Jones JM, Sharkey LM, Tufik S, Epstein M, Letts VA, Meisler MH, Frankel WN, Escayg A.

Hum Mol Genet. 2009 May 1;18(9):1633-41. doi: 10.1093/hmg/ddp081. Epub 2009 Mar 2.

19.

SCN8A mutations in Chinese patients with early onset epileptic encephalopathy and benign infantile seizures.

Wang J, Gao H, Bao X, Zhang Q, Li J, Wei L, Wu X, Chen Y, Yu S.

BMC Med Genet. 2017 Sep 18;18(1):104. doi: 10.1186/s12881-017-0460-1.

20.

Hypothalamic-pituitary-adrenal axis and behavioral dysfunction following early binge-like prenatal alcohol exposure in mice.

Wieczorek L, Fish EW, O'Leary-Moore SK, Parnell SE, Sulik KK.

Alcohol. 2015 May;49(3):207-17. doi: 10.1016/j.alcohol.2015.01.005. Epub 2015 Jan 26.

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