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Items: 1 to 20 of 70

1.

Targeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene.

Morano A, Angrisano T, Russo G, Landi R, Pezone A, Bartollino S, Zuchegna C, Babbio F, Bonapace IM, Allen B, Muller MT, Chiariotti L, Gottesman ME, Porcellini A, Avvedimento EV.

Nucleic Acids Res. 2014 Jan;42(2):804-21. doi: 10.1093/nar/gkt920. Epub 2013 Oct 16.

2.

GADD45α inhibition of DNMT1 dependent DNA methylation during homology directed DNA repair.

Lee B, Morano A, Porcellini A, Muller MT.

Nucleic Acids Res. 2012 Mar;40(6):2481-93. doi: 10.1093/nar/gkr1115. Epub 2011 Dec 1.

3.

DNA damage, homology-directed repair, and DNA methylation.

Cuozzo C, Porcellini A, Angrisano T, Morano A, Lee B, Di Pardo A, Messina S, Iuliano R, Fusco A, Santillo MR, Muller MT, Chiariotti L, Gottesman ME, Avvedimento EV.

PLoS Genet. 2007 Jul;3(7):e110.

4.

Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells.

Meilinger D, Fellinger K, Bultmann S, Rothbauer U, Bonapace IM, Klinkert WE, Spada F, Leonhardt H.

EMBO Rep. 2009 Nov;10(11):1259-64. doi: 10.1038/embor.2009.201. Epub 2009 Oct 2.

5.

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island.

O'Hagan HM, Mohammad HP, Baylin SB.

PLoS Genet. 2008 Aug 15;4(8):e1000155. doi: 10.1371/journal.pgen.1000155.

6.

UHRF1 plays a role in maintaining DNA methylation in mammalian cells.

Bostick M, Kim JK, Estève PO, Clark A, Pradhan S, Jacobsen SE.

Science. 2007 Sep 21;317(5845):1760-4. Epub 2007 Aug 2.

7.

Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase.

Kass EM, Helgadottir HR, Chen CC, Barbera M, Wang R, Westermark UK, Ludwig T, Moynahan ME, Jasin M.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5564-9. doi: 10.1073/pnas.1216824110. Epub 2013 Mar 18.

8.

Repair at single targeted DNA double-strand breaks in pluripotent and differentiated human cells.

Fung H, Weinstock DM.

PLoS One. 2011;6(5):e20514. doi: 10.1371/journal.pone.0020514. Epub 2011 May 25.

9.

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA.

Sharif J, Muto M, Takebayashi S, Suetake I, Iwamatsu A, Endo TA, Shinga J, Mizutani-Koseki Y, Toyoda T, Okamura K, Tajima S, Mitsuya K, Okano M, Koseki H.

Nature. 2007 Dec 6;450(7171):908-12. Epub 2007 Nov 11.

PMID:
17994007
10.

Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation.

Toh GW, O'Shaughnessy AM, Jimeno S, Dobbie IM, Grenon M, Maffini S, O'Rorke A, Lowndes NF.

DNA Repair (Amst). 2006 Jun 10;5(6):693-703. Epub 2006 May 2.

PMID:
16650810
11.

MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair.

Fang M, Xia F, Mahalingam M, Virbasius CM, Wajapeyee N, Green MR.

Mol Cell Biol. 2013 Jul;33(13):2635-47. doi: 10.1128/MCB.00167-13. Epub 2013 May 6.

12.

The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.

Goodarzi AA, Jeggo P, Lobrich M.

DNA Repair (Amst). 2010 Dec 10;9(12):1273-82. doi: 10.1016/j.dnarep.2010.09.013. Epub 2010 Oct 30. Review.

PMID:
21036673
13.

ABH2 couples regulation of ribosomal DNA transcription with DNA alkylation repair.

Li P, Gao S, Wang L, Yu F, Li J, Wang C, Li J, Wong J.

Cell Rep. 2013 Aug 29;4(4):817-29. doi: 10.1016/j.celrep.2013.07.027. Epub 2013 Aug 22.

14.

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

Barreto G, Schäfer A, Marhold J, Stach D, Swaminathan SK, Handa V, Döderlein G, Maltry N, Wu W, Lyko F, Niehrs C.

Nature. 2007 Feb 8;445(7128):671-5. Epub 2007 Jan 31.

PMID:
17268471
15.

Sensor and effector kinases in DNA damage checkpoint regulate capacity for homologous recombination repair of fission yeast in G2 phase.

Yasuhira S, Saito T, Maesawa C, Masuda T.

DNA Repair (Amst). 2012 Aug 1;11(8):666-75. doi: 10.1016/j.dnarep.2012.05.006. Epub 2012 Jun 8.

PMID:
22682874
16.

Functional connection between Rad51 and PML in homology-directed repair.

Boichuk S, Hu L, Makielski K, Pandolfi PP, Gjoerup OV.

PLoS One. 2011;6(10):e25814. doi: 10.1371/journal.pone.0025814. Epub 2011 Oct 5.

17.

DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

Palii SS, Van Emburgh BO, Sankpal UT, Brown KD, Robertson KD.

Mol Cell Biol. 2008 Jan;28(2):752-71. Epub 2007 Nov 8.

18.

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription.

Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T.

EMBO J. 2001 May 15;20(10):2536-44.

19.

GADD45A does not promote DNA demethylation.

Jin SG, Guo C, Pfeifer GP.

PLoS Genet. 2008 Mar 7;4(3):e1000013. doi: 10.1371/journal.pgen.1000013.

20.
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