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Items: 1 to 20 of 123

1.

The emerging and diverse roles of sirtuins in cancer: a clinical perspective.

Yuan H, Su L, Chen WY.

Onco Targets Ther. 2013 Oct 8;6:1399-416. doi: 10.2147/OTT.S37750. Review.

2.

Mechanism-based modulator discovery for sirtuin-catalyzed deacetylation reaction.

Zheng W.

Mini Rev Med Chem. 2013 Jan;13(1):132-54. Review.

PMID:
22876953
3.

Sorting out functions of sirtuins in cancer.

Roth M, Chen WY.

Oncogene. 2014 Mar 27;33(13):1609-20. doi: 10.1038/onc.2013.120. Epub 2013 Apr 22. Review.

4.

Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcription.

Rajendran R, Garva R, Krstic-Demonacos M, Demonacos C.

J Biomed Biotechnol. 2011;2011:368276. doi: 10.1155/2011/368276. Epub 2011 Sep 7. Review.

5.

Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH.

Madsen AS, Andersen C, Daoud M, Anderson KA, Laursen JS, Chakladar S, Huynh FK, Colaço AR, Backos DS, Fristrup P, Hirschey MD, Olsen CA.

J Biol Chem. 2016 Mar 25;291(13):7128-41. doi: 10.1074/jbc.M115.668699. Epub 2016 Feb 9.

6.

Sirtuins and their relevance to the kidney.

Hao CM, Haase VH.

J Am Soc Nephrol. 2010 Oct;21(10):1620-7. doi: 10.1681/ASN.2010010046. Epub 2010 Jul 1. Review.

7.

Protective effects of sirtuins in cardiovascular diseases: from bench to bedside.

Winnik S, Auwerx J, Sinclair DA, Matter CM.

Eur Heart J. 2015 Dec 21;36(48):3404-12. doi: 10.1093/eurheartj/ehv290. Epub 2015 Jun 25. Review.

8.

Regulation of sirtuin function by posttranslational modifications.

Flick F, Lüscher B.

Front Pharmacol. 2012 Feb 28;3:29. doi: 10.3389/fphar.2012.00029. eCollection 2012.

9.

SirT3 and p53 Deacetylation in Aging and Cancer.

Chen J, Wang A, Chen Q.

J Cell Physiol. 2017 Sep;232(9):2308-2311. doi: 10.1002/jcp.25669. Epub 2017 Apr 10. Review.

PMID:
27791271
10.

Role of sirtuins in ischemia-reperfusion injury.

Pantazi E, Zaouali MA, Bejaoui M, Folch-Puy E, Ben Abdennebi H, Roselló-Catafau J.

World J Gastroenterol. 2013;19(43):7594-602. doi: 10.3748/wjg.v19.i43.7594. Review.

11.

A mini-review on Sirtuin activity assays.

Li Y, Liu T, Liao S, Li Y, Lan Y, Wang A, Wang Y, He B.

Biochem Biophys Res Commun. 2015 Nov 20;467(3):459-66. doi: 10.1016/j.bbrc.2015.09.172. Epub 2015 Oct 9. Review.

PMID:
26456653
12.

Mitochondrial Sirtuins in Cancer: Emerging Roles and Therapeutic Potential.

George J, Ahmad N.

Cancer Res. 2016 May 1;76(9):2500-6. doi: 10.1158/0008-5472.CAN-15-2733. Epub 2016 Apr 20. Review.

13.

Sirtuin inhibitors as anticancer agents.

Hu J, Jing H, Lin H.

Future Med Chem. 2014 May;6(8):945-66. doi: 10.4155/fmc.14.44. Review.

14.

Structures, substrates, and regulators of Mammalian sirtuins - opportunities and challenges for drug development.

Moniot S, Weyand M, Steegborn C.

Front Pharmacol. 2012 Feb 9;3:16. doi: 10.3389/fphar.2012.00016. eCollection 2012.

15.

Sirtuin deacetylases in neurodegenerative diseases of aging.

Herskovits AZ, Guarente L.

Cell Res. 2013 Jun;23(6):746-58. doi: 10.1038/cr.2013.70. Epub 2013 May 21. Review.

16.

Sirtuins in glucose and lipid metabolism.

Ye X, Li M, Hou T, Gao T, Zhu WG, Yang Y.

Oncotarget. 2017 Jan 3;8(1):1845-1859. doi: 10.18632/oncotarget.12157. Review.

17.

Sirtuin functions in health and disease.

Yamamoto H, Schoonjans K, Auwerx J.

Mol Endocrinol. 2007 Aug;21(8):1745-55. Epub 2007 Apr 24. Review.

PMID:
17456799
18.

Sirtuins and disease: the road ahead.

Carafa V, Nebbioso A, Altucci L.

Front Pharmacol. 2012 Jan 31;3:4. doi: 10.3389/fphar.2012.00004. eCollection 2012.

19.

Sirtuin mechanism and inhibition: explored with N(ε)-acetyl-lysine analogs.

Hirsch BM, Zheng W.

Mol Biosyst. 2011 Jan;7(1):16-28. doi: 10.1039/c0mb00033g. Epub 2010 Sep 15. Review.

PMID:
20842312
20.

The role of sirtuins in cellular homeostasis.

Kupis W, Pałyga J, Tomal E, Niewiadomska E.

J Physiol Biochem. 2016 Sep;72(3):371-80. doi: 10.1007/s13105-016-0492-6. Epub 2016 May 6. Review.

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