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Items: 1 to 20 of 154

1.

EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis.

Zhang P, Garnett J, Creighton CJ, Al Sannaa GA, Igram DR, Lazar A, Liu X, Liu C, Pollock RE.

J Pathol. 2014 Feb;232(3):308-18. doi: 10.1002/path.4294. Erratum in: J Pathol. 2014 Jul;233(3):320. Igram, Davis R [corrected to Ingram, Davis R].

2.

Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway.

Zhang P, Yang X, Ma X, Ingram DR, Lazar AJ, Torres KE, Pollock RE.

Mol Cancer. 2015 Mar 7;14:55. doi: 10.1186/s12943-015-0325-1.

3.

Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.

Tsang DP, Wu WK, Kang W, Lee YY, Wu F, Yu Z, Xiong L, Chan AW, Tong JH, Yang W, Li MS, Lau SS, Li X, Lee SD, Yang Y, Lai PB, Yu DY, Xu G, Lo KW, Chan MT, Wang H, Lee TL, Yu J, Wong N, Yip KY, To KF, Cheng AS.

J Pathol. 2016 Apr;238(5):651-64. doi: 10.1002/path.4688.

PMID:
26800240
4.

Gestational diabetes mellitus impairs fetal endothelial cell functions through a mechanism involving microRNA-101 and histone methyltransferase enhancer of zester homolog-2.

Floris I, Descamps B, Vardeu A, Mitić T, Posadino AM, Shantikumar S, Sala-Newby G, Capobianco G, Mangialardi G, Howard L, Dessole S, Urrutia R, Pintus G, Emanueli C.

Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):664-74. doi: 10.1161/ATVBAHA.114.304730. Epub 2015 Jan 22.

5.

EZH2 promotes angiogenesis through inhibition of miR-1/Endothelin-1 axis in nasopharyngeal carcinoma.

Lu J, Zhao FP, Peng Z, Zhang MW, Lin SX, Liang BJ, Zhang B, Liu X, Wang L, Li G, Tian WD, Peng Y, He ML, Li XP.

Oncotarget. 2014 Nov 30;5(22):11319-32.

6.

Carcinogenesis of intraductal papillary mucinous neoplasm of the pancreas: loss of microRNA-101 promotes overexpression of histone methyltransferase EZH2.

Nakahara O, Takamori H, Iwatsuki M, Baba Y, Sakamoto Y, Tanaka H, Chikamoto A, Horino K, Beppu T, Kanemitsu K, Honda Y, Iyama K, Baba H.

Ann Surg Oncol. 2012 Jul;19 Suppl 3:S565-71. doi: 10.1245/s10434-011-2068-6. Epub 2011 Sep 20.

PMID:
21932133
7.

Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours.

Subramanian S, Thayanithy V, West RB, Lee CH, Beck AH, Zhu S, Downs-Kelly E, Montgomery K, Goldblum JR, Hogendoorn PC, Corless CL, Oliveira AM, Dry SM, Nielsen TO, Rubin BP, Fletcher JA, Fletcher CD, van de Rijn M.

J Pathol. 2010 Jan;220(1):58-70. doi: 10.1002/path.2633.

8.

Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31.

Zhang Q, Padi SK, Tindall DJ, Guo B.

Cell Death Dis. 2014 Oct 23;5:e1486. doi: 10.1038/cddis.2014.454.

9.

MicroRNA-204 critically regulates carcinogenesis in malignant peripheral nerve sheath tumors.

Gong M, Ma J, Li M, Zhou M, Hock JM, Yu X.

Neuro Oncol. 2012 Aug;14(8):1007-17. doi: 10.1093/neuonc/nos124. Epub 2012 Jun 19.

10.

Posttranscriptional silencing of the lncRNA MALAT1 by miR-217 inhibits the epithelial-mesenchymal transition via enhancer of zeste homolog 2 in the malignant transformation of HBE cells induced by cigarette smoke extract.

Lu L, Luo F, Liu Y, Liu X, Shi L, Lu X, Liu Q.

Toxicol Appl Pharmacol. 2015 Dec 1;289(2):276-85. doi: 10.1016/j.taap.2015.09.016. Epub 2015 Sep 28.

PMID:
26415832
11.

MiR-138 inhibits tumor growth through repression of EZH2 in non-small cell lung cancer.

Zhang H, Zhang H, Zhao M, Lv Z, Zhang X, Qin X, Wang H, Wang S, Su J, Lv X, Liu H, Du W, Zhou W, Chen X, Fei K.

Cell Physiol Biochem. 2013;31(1):56-65. doi: 10.1159/000343349. Epub 2013 Jan 15.

12.

Down-regulation of the miR-25 and miR-30d contributes to the development of anaplastic thyroid carcinoma targeting the polycomb protein EZH2.

Esposito F, Tornincasa M, Pallante P, Federico A, Borbone E, Pierantoni GM, Fusco A.

J Clin Endocrinol Metab. 2012 May;97(5):E710-8. doi: 10.1210/jc.2011-3068. Epub 2012 Mar 7.

PMID:
22399519
13.

MicroRNA-21 correlates with tumorigenesis in malignant peripheral nerve sheath tumor (MPNST) via programmed cell death protein 4 (PDCD4).

Itani S, Kunisada T, Morimoto Y, Yoshida A, Sasaki T, Ito S, Ouchida M, Sugihara S, Shimizu K, Ozaki T.

J Cancer Res Clin Oncol. 2012 Sep;138(9):1501-9. doi: 10.1007/s00432-012-1223-1. Epub 2012 Apr 22.

PMID:
22526161
14.

Enhancer of zeste homolog 2 (EZH2) promotes tumour cell migration and invasion via epigenetic repression of E-cadherin in renal cell carcinoma.

Liu L, Xu Z, Zhong L, Wang H, Jiang S, Long Q, Xu J, Guo J.

BJU Int. 2016 Feb;117(2):351-62. doi: 10.1111/bju.12702. Epub 2015 Apr 21.

15.

MicroRNA-101 exerts tumor-suppressive functions in non-small cell lung cancer through directly targeting enhancer of zeste homolog 2.

Zhang JG, Guo JF, Liu DL, Liu Q, Wang JJ.

J Thorac Oncol. 2011 Apr;6(4):671-8. doi: 10.1097/JTO.0b013e318208eb35.

16.

Polycomb repressor complex-2 is a novel target for mesothelioma therapy.

Kemp CD, Rao M, Xi S, Inchauste S, Mani H, Fetsch P, Filie A, Zhang M, Hong JA, Walker RL, Zhu YJ, Ripley RT, Mathur A, Liu F, Yang M, Meltzer PA, Marquez VE, De Rienzo A, Bueno R, Schrump DS.

Clin Cancer Res. 2012 Jan 1;18(1):77-90. doi: 10.1158/1078-0432.CCR-11-0962. Epub 2011 Oct 25.

17.

MicroRNA-1297 regulates hepatocellular carcinoma cell proliferation and apoptosis by targeting EZH2.

Liu F, He Y, Shu R, Wang S.

Int J Clin Exp Pathol. 2015 May 1;8(5):4972-80. eCollection 2015.

18.

MiR-340 impedes the progression of laryngeal squamous cell carcinoma by targeting EZH2.

Yu W, Zhang G, Lu B, Li J, Wu Z, Ma H, Wang H, Lian R.

Gene. 2016 Feb 15;577(2):193-201. doi: 10.1016/j.gene.2015.11.045. Epub 2015 Dec 2.

PMID:
26656176
19.

MiR-214 targets β-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma.

Xia H, Ooi LL, Hui KM.

PLoS One. 2012;7(9):e44206. doi: 10.1371/journal.pone.0044206. Epub 2012 Sep 4. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/1be2a62e-45a1-4c13-9a8d-f265005a21e0.

20.

Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis.

Zhang Q, Zhao W, Ye C, Zhuang J, Chang C, Li Y, Huang X, Shen L, Li Y, Cui Y, Song J, Shen B, Eliaz I, Huang R, Ying H, Guo H, Yan J.

Oncotarget. 2015 Nov 10;6(35):37335-48. doi: 10.18632/oncotarget.6135.

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