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Items: 1 to 20 of 270

1.

TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.

Parsons KS, Hsu AC, Wark PA.

Clin Exp Allergy. 2014 Jan;44(1):91-101. doi: 10.1111/cea.12218.

PMID:
24131248
2.

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.

Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB.

J Immunol. 2009 Dec 1;183(11):6989-97. doi: 10.4049/jimmunol.0901386. Epub 2009 Nov 4.

3.

Impaired innate interferon induction in severe therapy resistant atopic asthmatic children.

Edwards MR, Regamey N, Vareille M, Kieninger E, Gupta A, Shoemark A, Saglani S, Sykes A, Macintyre J, Davies J, Bossley C, Bush A, Johnston SL.

Mucosal Immunol. 2013 Jul;6(4):797-806. doi: 10.1038/mi.2012.118. Epub 2012 Dec 5.

4.

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium.

Slater L, Bartlett NW, Haas JJ, Zhu J, Message SD, Walton RP, Sykes A, Dahdaleh S, Clarke DL, Belvisi MG, Kon OM, Fujita T, Jeffery PK, Johnston SL, Edwards MR.

PLoS Pathog. 2010 Nov 4;6(11):e1001178. doi: 10.1371/journal.ppat.1001178. Erratum in: PLoS Pathog. 2012 Apr;8(4): doi/10.1371/annotation/c3f58c59-a42f-495b-a4f2-d74d55d72166.

5.

MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness.

Wang Q, Miller DJ, Bowman ER, Nagarkar DR, Schneider D, Zhao Y, Linn MJ, Goldsmith AM, Bentley JK, Sajjan US, Hershenson MB.

PLoS Pathog. 2011 May;7(5):e1002070. doi: 10.1371/journal.ppat.1002070. Epub 2011 May 26.

6.

Rhinovirus 16-induced IFN-α and IFN-β are deficient in bronchoalveolar lavage cells in asthmatic patients.

Sykes A, Edwards MR, Macintyre J, del Rosario A, Bakhsoliani E, Trujillo-Torralbo MB, Kon OM, Mallia P, McHale M, Johnston SL.

J Allergy Clin Immunol. 2012 Jun;129(6):1506-1514.e6. doi: 10.1016/j.jaci.2012.03.044.

PMID:
22657407
7.

Exogenous IFN-β has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus.

Cakebread JA, Xu Y, Grainge C, Kehagia V, Howarth PH, Holgate ST, Davies DE.

J Allergy Clin Immunol. 2011 May;127(5):1148-54.e9. doi: 10.1016/j.jaci.2011.01.023. Epub 2011 Feb 16.

PMID:
21329968
8.

Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD.

Baines KJ, Hsu AC, Tooze M, Gunawardhana LP, Gibson PG, Wark PA.

Respir Res. 2013 Feb 6;14:15. doi: 10.1186/1465-9921-14-15.

9.

Rhinoviral stimuli, epithelial factors and ATP signalling contribute to bronchial smooth muscle production of IL-33.

Calvén J, Akbarshahi H, Menzel M, Ayata CK, Idzko M, Bjermer L, Uller L.

J Transl Med. 2015 Aug 29;13:281. doi: 10.1186/s12967-015-0645-3.

10.

Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells.

Zhou L, Li JL, Zhou Y, Liu JB, Zhuang K, Gao JF, Liu S, Sang M, Wu JG, Ho WZ.

Mol Hum Reprod. 2015 Dec;21(12):917-29. doi: 10.1093/molehr/gav058. Epub 2015 Oct 26.

11.

Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells.

Contoli M, Ito K, Padovani A, Poletti D, Marku B, Edwards MR, Stanciu LA, Gnesini G, Pastore A, Spanevello A, Morelli P, Johnston SL, Caramori G, Papi A.

Allergy. 2015 Aug;70(8):910-20. doi: 10.1111/all.12627. Epub 2015 Apr 24.

12.

Allergic environment enhances airway epithelial pro-inflammatory responses to rhinovirus infection.

Herbert C, Do K, Chiu V, Garthwaite L, Chen Y, Young PM, Traini D, Kumar RK.

Clin Sci (Lond). 2017 Mar 1;131(6):499-509. doi: 10.1042/CS20160939. Epub 2017 Jan 23.

PMID:
28115681
13.

Rhinovirus and dsRNA induce RIG-I-like receptors and expression of interferon β and λ1 in human bronchial smooth muscle cells.

Calvén J, Yudina Y, Uller L.

PLoS One. 2013 Apr 29;8(4):e62718. doi: 10.1371/journal.pone.0062718. Print 2013.

14.

Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in Toll-like receptor 3 signaling in normal human mesangial cells.

Imaizumi T, Aizawa-Yashiro T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Tatsuta T, Xing F, Hayakari R, Meng P, Tanaka H.

Am J Nephrol. 2013;37(2):118-25. doi: 10.1159/000346415. Epub 2013 Jan 29.

PMID:
23363937
15.

Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells.

Vareille M, Kieninger E, Alves MP, Kopf BS, Möller A, Geiser T, Johnston SL, Edwards MR, Regamey N.

Thorax. 2012 Jun;67(6):517-25. doi: 10.1136/thoraxjnl-2011-200405. Epub 2012 Jan 2. Retraction in: Thorax. 2013 Sep;68(9):886.

PMID:
22213737
16.

Diversity in the bronchial epithelial cell response to infection with different rhinovirus strains.

Wark PA, Grissell T, Davies B, See H, Gibson PG.

Respirology. 2009 Mar;14(2):180-6. doi: 10.1111/j.1440-1843.2009.01480.x. Epub 2009 Feb 4.

PMID:
19207121
17.

Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus.

Wark PA, Johnston SL, Bucchieri F, Powell R, Puddicombe S, Laza-Stanca V, Holgate ST, Davies DE.

J Exp Med. 2005 Mar 21;201(6):937-47.

18.

Viral stimuli trigger exaggerated thymic stromal lymphopoietin expression by chronic obstructive pulmonary disease epithelium: role of endosomal TLR3 and cytosolic RIG-I-like helicases.

Calvén J, Yudina Y, Hallgren O, Westergren-Thorsson G, Davies DE, Brandelius A, Uller L.

J Innate Immun. 2012;4(1):86-99. doi: 10.1159/000329131. Epub 2011 Jun 20.

19.

Human rhinovirus recognition in non-immune cells is mediated by Toll-like receptors and MDA-5, which trigger a synergetic pro-inflammatory immune response.

Triantafilou K, Vakakis E, Richer EA, Evans GL, Villiers JP, Triantafilou M.

Virulence. 2011 Jan-Feb;2(1):22-9. Epub 2011 Jan 1.

20.

Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells.

Yan K, Zhu W, Yu L, Li N, Zhang X, Liu P, Chen Q, Chen Y, Han D.

Mol Cell Endocrinol. 2013 Jun 15;372(1-2):73-85. doi: 10.1016/j.mce.2013.03.027. Epub 2013 Apr 6.

PMID:
23567548

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