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Items: 1 to 20 of 239

1.

Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production.

Man SM, Tourlomousis P, Hopkins L, Monie TP, Fitzgerald KA, Bryant CE.

J Immunol. 2013 Nov 15;191(10):5239-46. doi: 10.4049/jimmunol.1301581. Epub 2013 Oct 11.

2.

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

Man SM, Hopkins LJ, Nugent E, Cox S, Glück IM, Tourlomousis P, Wright JA, Cicuta P, Monie TP, Bryant CE.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7403-8. doi: 10.1073/pnas.1402911111. Epub 2014 May 6.

3.

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella.

Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, Monack DM.

J Exp Med. 2010 Aug 2;207(8):1745-55. doi: 10.1084/jem.20100257. Epub 2010 Jul 5.

4.

The CARD plays a critical role in ASC foci formation and inflammasome signalling.

Proell M, Gerlic M, Mace PD, Reed JC, Riedl SJ.

Biochem J. 2013 Feb 1;449(3):613-21. doi: 10.1042/BJ20121198.

5.

Cirtical role for Salmonella effector SopB in regulating inflammasome activation.

Hu GQ, Song PX, Chen W, Qi S, Yu SX, Du CT, Deng XM, Ouyang HS, Yang YJ.

Mol Immunol. 2017 Oct;90:280-286. doi: 10.1016/j.molimm.2017.07.011. Epub 2017 Aug 30. Erratum in: Mol Immunol. 2019 Jan;105:283.

PMID:
28846926
6.

A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB.

PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026. Epub 2011 Apr 21.

7.

Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, Cunha LD, Zamboni DS, Oliveira SC.

J Immunol. 2013 Apr 1;190(7):3629-38. doi: 10.4049/jimmunol.1202817. Epub 2013 Mar 4.

8.

Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes.

Wu J, Fernandes-Alnemri T, Alnemri ES.

J Clin Immunol. 2010 Sep;30(5):693-702. doi: 10.1007/s10875-010-9425-2. Epub 2010 May 20.

9.

Novel role of PKR in inflammasome activation and HMGB1 release.

Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ.

Nature. 2012 Aug 30;488(7413):670-4. doi: 10.1038/nature11290.

10.

Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes.

Tsuchiya K, Hara H, Kawamura I, Nomura T, Yamamoto T, Daim S, Dewamitta SR, Shen Y, Fang R, Mitsuyama M.

J Immunol. 2010 Jul 15;185(2):1186-95. doi: 10.4049/jimmunol.1001058. Epub 2010 Jun 21.

11.

Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function.

Guey B, Bodnar M, Manié SN, Tardivel A, Petrilli V.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17254-9. doi: 10.1073/pnas.1415756111. Epub 2014 Nov 17.

12.

Oxidized phosphatidylcholine induces the activation of NLRP3 inflammasome in macrophages.

Yeon SH, Yang G, Lee HE, Lee JY.

J Leukoc Biol. 2017 Jan;101(1):205-215. doi: 10.1189/jlb.3VMA1215-579RR. Epub 2016 Jun 2.

PMID:
27256568
13.

Asc modulates the function of NLRC4 in response to infection of macrophages by Legionella pneumophila.

Case CL, Roy CR.

MBio. 2011 Sep 1;2(4). pii: e00117-11. doi: 10.1128/mBio.00117-11. Print 2011.

14.

Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.

Oosting M, Buffen K, Malireddi SR, Sturm P, Verschueren I, Koenders MI, van de Veerdonk FL, van der Meer JW, Netea MG, Kanneganti TD, Joosten LA.

Arthritis Res Ther. 2012 Nov 13;14(6):R247. doi: 10.1186/ar4090.

15.

Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzi replication and survival is dispensable in NLRP3-/- macrophages.

Dey N, Sinha M, Gupta S, Gonzalez MN, Fang R, Endsley JJ, Luxon BA, Garg NJ.

PLoS One. 2014 Nov 5;9(11):e111539. doi: 10.1371/journal.pone.0111539. eCollection 2014.

16.

NLRP3 recruitment by NLRC4 during Salmonella infection.

Qu Y, Misaghi S, Newton K, Maltzman A, Izrael-Tomasevic A, Arnott D, Dixit VM.

J Exp Med. 2016 May 30;213(6):877-85. doi: 10.1084/jem.20132234. Epub 2016 May 2.

17.

Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells.

Antonopoulos C, El Sanadi C, Kaiser WJ, Mocarski ES, Dubyak GR.

J Immunol. 2013 Nov 1;191(9):4789-803. doi: 10.4049/jimmunol.1300645. Epub 2013 Sep 27.

18.

Shiga Toxins Activate the NLRP3 Inflammasome Pathway To Promote Both Production of the Proinflammatory Cytokine Interleukin-1β and Apoptotic Cell Death.

Lee MS, Kwon H, Lee EY, Kim DJ, Park JH, Tesh VL, Oh TK, Kim MH.

Infect Immun. 2015 Oct 26;84(1):172-86. doi: 10.1128/IAI.01095-15. Print 2016 Jan.

19.

β-arrestin1 is critical for the full activation of NLRP3 and NLRC4 inflammasomes.

Mao K, Chen S, Wang Y, Zeng Y, Ma Y, Hu Y, Zhang H, Sun S, Wu X, Meng G, Pei G, Sun B.

J Immunol. 2015 Feb 15;194(4):1867-73. doi: 10.4049/jimmunol.1401989. Epub 2015 Jan 12.

20.

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.

Conos SA, Chen KW, De Nardo D, Hara H, Whitehead L, Núñez G, Masters SL, Murphy JM, Schroder K, Vaux DL, Lawlor KE, Lindqvist LM, Vince JE.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E961-E969. doi: 10.1073/pnas.1613305114. Epub 2017 Jan 17. Erratum in: Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5762-E5763.

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