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Items: 1 to 20 of 101

1.

Pathology in drug discovery and development.

Jubb AM, Koeppen H, Reis-Filho JS.

J Pathol. 2014 Jan;232(2):99-102. doi: 10.1002/path.4290.

PMID:
24122335
2.

Biomarkers: refining diagnosis and expediting drug development - reality, aspiration and the role of open innovation.

Salter H, Holland R.

J Intern Med. 2014 Sep;276(3):215-28. doi: 10.1111/joim.12234. Epub 2014 Mar 28. Review.

3.

Cancer Drug Development: New Targets for Cancer Treatment.

Curt GA.

Oncologist. 1996;1(3):II-III.

PMID:
10387987
4.

US FDA perspective on challenges in co-developing in vitro companion diagnostics and targeted cancer therapeutics.

Philip R, Carrington L, Chan M.

Bioanalysis. 2011 Feb;3(4):383-9. doi: 10.4155/bio.11.1.

PMID:
21338257
5.

New science-based endpoints to accelerate oncology drug development.

Kelloff GJ, Sigman CC.

Eur J Cancer. 2005 Mar;41(4):491-501. Epub 2005 Jan 22. Review.

PMID:
15737552
6.

Personalized oncology: recent advances and future challenges.

Kalia M.

Metabolism. 2013 Jan;62 Suppl 1:S11-4. doi: 10.1016/j.metabol.2012.08.016. Epub 2012 Sep 19. Review.

PMID:
22999010
7.

The biomarker is not the end.

Nohaile M.

Drug Discov Today. 2011 Oct;16(19-20):878-83. doi: 10.1016/j.drudis.2011.08.011. Epub 2011 Aug 24. Review.

PMID:
21888986
8.

Challenges of biomarkers in drug discovery and development.

Goodsaid F.

Expert Opin Drug Discov. 2012 Jun;7(6):457-61. doi: 10.1517/17460441.2012.679615. Epub 2012 Apr 4.

PMID:
22471322
9.

Mouse tumour models to guide drug development and identify resistance mechanisms.

Das Thakur M, Pryer NK, Singh M.

J Pathol. 2014 Jan;232(2):103-11. doi: 10.1002/path.4285. Review.

PMID:
24122209
10.

Predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance.

Dietel M, Jöhrens K, Laffert M, Hummel M, Bläker H, Müller BM, Lehmann A, Denkert C, Heppner FL, Koch A, Sers C, Anagnostopoulos I.

Cancer Gene Ther. 2013 Apr;20(4):211-21. doi: 10.1038/cgt.2013.13. Epub 2013 Mar 15. Review.

PMID:
23492822
11.

[Biomarkers: "Found in translation"].

Lockhart BP, Walther B.

Med Sci (Paris). 2009 Apr;25(4):423-30. doi: 10.1051/medsci/2009254423. Review. French.

12.

Anticancer Drug Development: The Way Forward.

Connors T.

Oncologist. 1996;1(3):180-181.

13.

The zebrafish: a powerful platform for in vivo, HTS drug discovery.

Delvecchio C, Tiefenbach J, Krause HM.

Assay Drug Dev Technol. 2011 Aug;9(4):354-61. doi: 10.1089/adt.2010.0346. Epub 2011 Feb 10. Review.

PMID:
21309713
14.

Biomarkers in Pharmaceutical Research.

Zhao X, Modur V, Carayannopoulos LN, Laterza OF.

Clin Chem. 2015 Nov;61(11):1343-53. doi: 10.1373/clinchem.2014.231712. Epub 2015 Sep 25. Review.

15.

Applications of imaging biomarkers in the early clinical development of central nervous system therapeutic agents.

Cole PE, Schwarz AJ, Schmidt ME.

Clin Pharmacol Ther. 2012 Feb;91(2):315-20. doi: 10.1038/clpt.2011.286. Epub 2012 Jan 4. Review.

PMID:
22218072
16.

Applications of molecular imaging in drug discovery and development process.

Ahn BC.

Curr Pharm Biotechnol. 2011 Apr;12(4):459-68.

PMID:
21342108
17.

Personalized medicine and development of targeted therapies: The upcoming challenge for diagnostic molecular pathology. A review.

Dietel M, Sers C.

Virchows Arch. 2006 Jun;448(6):744-55. Epub 2006 Apr 22. Review.

PMID:
16736190
18.

Translational paradigms in pharmacology and drug discovery.

Mullane K, Winquist RJ, Williams M.

Biochem Pharmacol. 2014 Jan 1;87(1):189-210. doi: 10.1016/j.bcp.2013.10.019. Epub 2013 Oct 30. Review.

PMID:
24184503
19.

Horizon scanning for novel therapeutics for the treatment of prostate cancer.

Bianchini D, Zivi A, Sandhu S, de Bono JS.

Expert Opin Investig Drugs. 2010 Dec;19(12):1487-502. doi: 10.1517/13543784.2010.514261. Epub 2010 Sep 24. Review. Retraction in: Expert Opin Investig Drugs. 2012 Oct;21(10):1591.

PMID:
20868208
20.

Accelerating safe drug development: an ideal approach to approval.

Grever MR.

Hematology Am Soc Hematol Educ Program. 2013;2013:24-9. doi: 10.1182/asheducation-2013.1.24. Review.

PMID:
24319158

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