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Items: 1 to 20 of 103

1.

Glutamate dehydrogenase: structure, allosteric regulation, and role in insulin homeostasis.

Li M, Li C, Allen A, Stanley CA, Smith TJ.

Neurochem Res. 2014;39(3):433-45. doi: 10.1007/s11064-013-1173-2. Epub 2013 Oct 12. Review.

PMID:
24122080
2.

The structure and allosteric regulation of mammalian glutamate dehydrogenase.

Li M, Li C, Allen A, Stanley CA, Smith TJ.

Arch Biochem Biophys. 2012 Mar 15;519(2):69-80. doi: 10.1016/j.abb.2011.10.015. Epub 2011 Nov 4. Review.

3.

Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site.

Li C, Li M, Chen P, Narayan S, Matschinsky FM, Bennett MJ, Stanley CA, Smith TJ.

J Biol Chem. 2011 Sep 30;286(39):34164-74. doi: 10.1074/jbc.M111.268599. Epub 2011 Aug 3.

4.

Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics.

Li M, Smith CJ, Walker MT, Smith TJ.

J Biol Chem. 2009 Aug 21;284(34):22988-3000. doi: 10.1074/jbc.M109.020222. Epub 2009 Jun 15.

5.

Regulation of glutamate metabolism and insulin secretion by glutamate dehydrogenase in hypoglycemic children.

Stanley CA.

Am J Clin Nutr. 2009 Sep;90(3):862S-866S. doi: 10.3945/ajcn.2009.27462AA. Epub 2009 Jul 22. Review.

6.

Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.

Fang J, Hsu BY, MacMullen CM, Poncz M, Smith TJ, Stanley CA.

Biochem J. 2002 Apr 1;363(Pt 1):81-7.

7.
8.

Green tea polyphenols modulate insulin secretion by inhibiting glutamate dehydrogenase.

Li C, Allen A, Kwagh J, Doliba NM, Qin W, Najafi H, Collins HW, Matschinsky FM, Stanley CA, Smith TJ.

J Biol Chem. 2006 Apr 14;281(15):10214-21. Epub 2006 Feb 13.

9.

Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase.

Stanley CA.

Neurochem Int. 2011 Sep;59(4):465-72. doi: 10.1016/j.neuint.2010.11.017. Epub 2010 Dec 2. Review.

10.
11.

Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.

Grimaldi M, Karaca M, Latini L, Brioudes E, Schalch T, Maechler P.

Hum Mol Genet. 2017 Sep 15;26(18):3453-3465. doi: 10.1093/hmg/ddx213.

PMID:
28911206
12.

Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation.

Banerjee S, Schmidt T, Fang J, Stanley CA, Smith TJ.

Biochemistry. 2003 Apr 1;42(12):3446-56.

PMID:
12653548
13.

Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation.

Allen A, Kwagh J, Fang J, Stanley CA, Smith TJ.

Biochemistry. 2004 Nov 16;43(45):14431-43.

PMID:
15533048
14.

Structural basis for leucine-induced allosteric activation of glutamate dehydrogenase.

Tomita T, Kuzuyama T, Nishiyama M.

J Biol Chem. 2011 Oct 28;286(43):37406-13. doi: 10.1074/jbc.M111.260265. Epub 2011 Sep 6.

15.

Hyperinsulinism/hyperammonemia syndrome in children with regulatory mutations in the inhibitory guanosine triphosphate-binding domain of glutamate dehydrogenase.

MacMullen C, Fang J, Hsu BY, Kelly A, de Lonlay-Debeney P, Saudubray JM, Ganguly A, Smith TJ, Stanley CA; Hyperinsulinism/hyperammonemia Contributing Investigators.

J Clin Endocrinol Metab. 2001 Apr;86(4):1782-7.

PMID:
11297618
17.

Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.

Smith TJ, Peterson PE, Schmidt T, Fang J, Stanley CA.

J Mol Biol. 2001 Mar 23;307(2):707-20.

PMID:
11254391
18.

The structure and allosteric regulation of glutamate dehydrogenase.

Li M, Li C, Allen A, Stanley CA, Smith TJ.

Neurochem Int. 2011 Sep;59(4):445-55. doi: 10.1016/j.neuint.2010.10.017. Epub 2010 Nov 9. Review.

19.

Identification of a Novel Activator of Mammalian Glutamate Dehydrogenase.

Smith HQ, Smith TJ.

Biochemistry. 2016 Nov 29;55(47):6568-6576. Epub 2016 Nov 14.

PMID:
27808506

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