Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 91

1.

Crystal structure of human CK2α at 1.06 Å resolution.

Kinoshita T, Nakaniwa T, Sekiguchi Y, Sogabe Y, Sakurai A, Nakamura S, Nakanishi I.

J Synchrotron Radiat. 2013 Nov;20(Pt 6):974-9. doi: 10.1107/S0909049513020785. Epub 2013 Oct 2.

2.

First inactive conformation of CK2 alpha, the catalytic subunit of protein kinase CK2.

Raaf J, Issinger OG, Niefind K.

J Mol Biol. 2009 Mar 13;386(5):1212-21. doi: 10.1016/j.jmb.2009.01.033. Epub 2009 Jan 24.

PMID:
19361447
3.

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

Ermakova I, Boldyreff B, Issinger OG, Niefind K.

J Mol Biol. 2003 Jul 25;330(5):925-34.

PMID:
12860116
4.

Low-density crystal packing of human protein kinase CK2 catalytic subunit in complex with resorufin or other ligands: a tool to study the unique hinge-region plasticity of the enzyme without packing bias.

Klopffleisch K, Issinger OG, Niefind K.

Acta Crystallogr D Biol Crystallogr. 2012 Aug;68(Pt 8):883-92. doi: 10.1107/S0907444912016587. Epub 2012 Jul 7.

PMID:
22868753
5.

The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin.

Raaf J, Klopffleisch K, Issinger OG, Niefind K.

J Mol Biol. 2008 Mar 14;377(1):1-8. doi: 10.1016/j.jmb.2008.01.008. Epub 2008 Jan 11.

PMID:
18242640
6.

Structure of the human protein kinase CK2 catalytic subunit CK2α' and interaction thermodynamics with the regulatory subunit CK2β.

Bischoff N, Olsen B, Raaf J, Bretner M, Issinger OG, Niefind K.

J Mol Biol. 2011 Mar 18;407(1):1-12. doi: 10.1016/j.jmb.2011.01.020. Epub 2011 Jan 15.

PMID:
21241709
7.

First structure of protein kinase CK2 catalytic subunit with an effective CK2β-competitive ligand.

Raaf J, Guerra B, Neundorf I, Bopp B, Issinger OG, Jose J, Pietsch M, Niefind K.

ACS Chem Biol. 2013 May 17;8(5):901-7. doi: 10.1021/cb3007133. Epub 2013 Mar 18.

PMID:
23474121
8.

Protein kinase CK2 in health and disease: Protein kinase CK2: from structures to insights.

Niefind K, Raaf J, Issinger OG.

Cell Mol Life Sci. 2009 Jun;66(11-12):1800-16. doi: 10.1007/s00018-009-9149-8. Review. Erratum in: Cell Mol Life Sci.2009 Nov;66(21):3535-6.

PMID:
19387553
9.

Enzymatic activity with an incomplete catalytic spine: insights from a comparative structural analysis of human CK2α and its paralogous isoform CK2α'.

Bischoff N, Raaf J, Olsen B, Bretner M, Issinger OG, Niefind K.

Mol Cell Biochem. 2011 Oct;356(1-2):57-65. doi: 10.1007/s11010-011-0948-5. Epub 2011 Jul 8.

PMID:
21739153
10.

Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate.

Yde CW, Ermakova I, Issinger OG, Niefind K.

J Mol Biol. 2005 Mar 25;347(2):399-414. Epub 2005 Jan 18.

PMID:
15740749
11.

Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1 A resolution.

Niefind K, Guerra B, Pinna LA, Issinger OG, Schomburg D.

EMBO J. 1998 May 1;17(9):2451-62.

12.

The interaction of CK2alpha and CK2beta, the subunits of protein kinase CK2, requires CK2beta in a preformed conformation and is enthalpically driven.

Raaf J, Brunstein E, Issinger OG, Niefind K.

Protein Sci. 2008 Dec;17(12):2180-6. doi: 10.1110/ps.037770.108. Epub 2008 Sep 29.

13.

Conformational plasticity of the catalytic subunit of protein kinase CK2 and its consequences for regulation and drug design.

Niefind K, Issinger OG.

Biochim Biophys Acta. 2010 Mar;1804(3):484-92. doi: 10.1016/j.bbapap.2009.09.022. Epub 2009 Sep 28. Review.

PMID:
19796713
14.
15.

The protein kinase CK2(Andante) holoenzyme structure supports proposed models of autoregulation and trans-autophosphorylation.

Schnitzler A, Olsen BB, Issinger OG, Niefind K.

J Mol Biol. 2014 May 1;426(9):1871-82. doi: 10.1016/j.jmb.2014.02.018. Epub 2014 Mar 1.

PMID:
24594356
16.

Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid.

Sekiguchi Y, Nakaniwa T, Kinoshita T, Nakanishi I, Kitaura K, Hirasawa A, Tsujimoto G, Tada T.

Bioorg Med Chem Lett. 2009 Jun 1;19(11):2920-3. doi: 10.1016/j.bmcl.2009.04.076. Epub 2009 Apr 22.

PMID:
19414254
17.

Structural and functional analysis of the flexible regions of the catalytic α-subunit of protein kinase CK2.

Papinutto E, Ranchio A, Lolli G, Pinna LA, Battistutta R.

J Struct Biol. 2012 Feb;177(2):382-91. doi: 10.1016/j.jsb.2011.12.007. Epub 2011 Dec 13.

PMID:
22186626
19.

Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction.

Laudet B, Barette C, Dulery V, Renaudet O, Dumy P, Metz A, Prudent R, Deshiere A, Dideberg O, Filhol O, Cochet C.

Biochem J. 2007 Dec 15;408(3):363-73.

20.

Interaction between CK2α and CK2β, the subunits of protein kinase CK2: thermodynamic contributions of key residues on the CK2α surface.

Raaf J, Bischoff N, Klopffleisch K, Brunstein E, Olsen BB, Vilk G, Litchfield DW, Issinger OG, Niefind K.

Biochemistry. 2011 Feb 1;50(4):512-22. doi: 10.1021/bi1013563. Epub 2010 Dec 31.

PMID:
21142136

Supplemental Content

Support Center