Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 347

1.

New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death.

Queiroz MJ, Peixoto D, Calhelha RC, Soares P, Dos Santos T, Lima RT, Campos JF, Abreu RM, Ferreira IC, Vasconcelos MH.

Eur J Med Chem. 2013 Nov;69:855-62. doi: 10.1016/j.ejmech.2013.09.023. Epub 2013 Sep 21.

PMID:
24121236
2.

Novel 6-[(hetero)arylamino]thieno[3,2-b]pyridines: synthesis and antitumoral activities.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, São-José Nascimento M.

Eur J Med Chem. 2010 Dec;45(12):5732-8. doi: 10.1016/j.ejmech.2010.09.030. Epub 2010 Sep 17.

PMID:
20934235
3.

Aminodi(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, effects in human tumor cells growth, cell cycle analysis, apoptosis and evaluation of toxicity using non-tumor cells.

Calhelha RC, Ferreira IC, Peixoto D, Abreu RM, Vale-Silva LA, Pinto E, Lima RT, Alvelos MI, Vasconcelos MH, Queiroz MJ.

Molecules. 2012 Mar 28;17(4):3834-43. doi: 10.3390/molecules17043834.

4.

Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki-Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Lima RT, Vasconcelos MH.

Eur J Med Chem. 2010 Dec;45(12):5628-34. doi: 10.1016/j.ejmech.2010.09.014. Epub 2010 Sep 17.

PMID:
20926160
5.

Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate derivatives: in vitro evaluation, cell cycle analysis and QSAR studies.

Abreu RM, Ferreira IC, Calhelha RC, Lima RT, Vasconcelos MH, Adega F, Chaves R, Queiroz MJ.

Eur J Med Chem. 2011 Dec;46(12):5800-6. doi: 10.1016/j.ejmech.2011.09.029. Epub 2011 Oct 6.

PMID:
22014996
6.

Synthesis and evaluation of tumor cell growth inhibition of methyl 3-amino-6-[(hetero)arylethynyl]thieno[3,2-b]pyridine-2-carboxylates. Structure-activity relationships, effects on the cell cycle and apoptosis.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Almeida GM, Vasconcelos MH.

Eur J Med Chem. 2011 Jan;46(1):236-40. doi: 10.1016/j.ejmech.2010.11.009. Epub 2010 Dec 8.

PMID:
21138784
7.

Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agents.

Romagnoli R, Baraldi PG, Kimatrai Salvador M, Preti D, Aghazadeh Tabrizi M, Bassetto M, Brancale A, Hamel E, Castagliuolo I, Bortolozzi R, Basso G, Viola G.

J Med Chem. 2013 Mar 28;56(6):2606-18. doi: 10.1021/jm400043d. Epub 2013 Mar 18.

8.

Synthesis and cytotoxicity of thieno[2,3-b]pyridine and furo[2,3-b]pyridine derivatives.

Hung JM, Arabshahi HJ, Leung E, Reynisson J, Barker D.

Eur J Med Chem. 2014 Oct 30;86:420-37. doi: 10.1016/j.ejmech.2014.09.001. Epub 2014 Sep 3.

PMID:
25194934
9.

Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.

Kandeel MM, Refaat HM, Kassab AE, Shahin IG, Abdelghany TM.

Eur J Med Chem. 2015 Jan 27;90:620-32. doi: 10.1016/j.ejmech.2014.12.009. Epub 2014 Dec 6.

PMID:
25499930
10.

Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison.

Karki R, Park C, Jun KY, Kadayat TM, Lee ES, Kwon Y.

Eur J Med Chem. 2015 Jan 27;90:360-78. doi: 10.1016/j.ejmech.2014.11.045. Epub 2014 Nov 24.

PMID:
25437622
11.

A novel anticancer agent, SKLB70359, inhibits human hepatic carcinoma cells proliferation via G0/G1 cell cycle arrest and apoptosis induction.

Dai XY, Zeng XX, Peng F, Han YY, Lin HJ, Xu YZ, Zhou T, Xie G, Deng Y, Mao YQ, Yu LT, Yang L, Zhao YL.

Cell Physiol Biochem. 2012;29(1-2):281-90. doi: 10.1159/000337609. Epub 2012 Mar 1.

12.

Synthesis of selenazolopyridine derivatives with capability to induce apoptosis in human breast carcinoma MCF-7 cells through scavenge of intracellular ROS.

Zhou M, Ji S, Wu Z, Li Y, Zheng W, Zhou H, Chen T.

Eur J Med Chem. 2015;96:92-7. doi: 10.1016/j.ejmech.2015.03.069. Epub 2015 Apr 1.

PMID:
25874334
13.

Synthesis and in vitro anti-proliferative effects of 3-(hetero)aryl substituted 3-[(prop-2-ynyloxy)(thiophen-2-yl)methyl]pyridine derivatives on various cancer cell lines.

Reddy Chamakura U, Sailaja E, Dulla B, Kalle AM, Bhavani S, Rambabu D, Kapavarapu R, Rao MV, Pal M.

Bioorg Med Chem Lett. 2014 Mar 1;24(5):1366-72. doi: 10.1016/j.bmcl.2014.01.044. Epub 2014 Jan 26.

PMID:
24513041
14.

Synthesis and antiproliferative activity of some new thieno[2,3-d]pyrimidin-4(3H)-ones containing 1,2,4-triazole and 1,3,4-thiadiazole moiety.

Mavrova ATs, Wesselinova D, Tsenov JA, Lubenov LA.

Eur J Med Chem. 2014 Oct 30;86:676-83. doi: 10.1016/j.ejmech.2014.09.032. Epub 2014 Sep 10.

PMID:
25222878
15.

Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives: the effect on apoptosis induction, cell cycle and proliferation.

Mingoia F, Di Sano C, Di Blasi F, Fazzari M, Martorana A, Almerico AM, Lauria A.

Eur J Med Chem. 2013 Jun;64:345-56. doi: 10.1016/j.ejmech.2013.03.046. Epub 2013 Apr 6.

PMID:
23644217
16.

Synthesis and anticancer activity of novel 2-pyridyl hexahyrocyclooctathieno[2,3-d]pyrimidine derivatives.

Kassab AE, Gedawy EM.

Eur J Med Chem. 2013 May;63:224-30. doi: 10.1016/j.ejmech.2013.02.011. Epub 2013 Feb 19.

PMID:
23501108
17.

Small molecular anticancer agent SKLB703 induces apoptosis in human hepatocellular carcinoma cells via the mitochondrial apoptotic pathway invitro and inhibits tumor growth invivo.

Xu YZ, Zheng RL, Zhou Y, Peng F, Lin HJ, Bu Q, Mao YQ, Yu LT, Yang L, Yang SY, Zhao YL.

Cancer Lett. 2011 Dec 26;313(1):44-53. doi: 10.1016/j.canlet.2011.08.025. Epub 2011 Sep 8.

PMID:
21944661
18.

Synthesis, antitumor screening and cell cycle analysis of novel benzothieno[3,2-b]pyran derivatives.

Zaher AF, Abuel-Maaty SM, El-Nassan HB, Amer SA, Abdelghany TM.

J Enzyme Inhib Med Chem. 2016;31(sup4):145-153. Epub 2016 Sep 2.

PMID:
27590401
19.

A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases.

Kwon HB, Park C, Jeon KH, Lee E, Park SE, Jun KY, Kadayat TM, Thapa P, Karki R, Na Y, Park MS, Rho SB, Lee ES, Kwon Y.

J Med Chem. 2015 Feb 12;58(3):1100-22. doi: 10.1021/jm501023q. Epub 2015 Feb 2.

PMID:
25603122
20.

Design, synthesis and in vitro antitumor activity of novel N-substituted-4-phenyl/benzylphthalazin-1-ones.

Eldehna WM, Ibrahim HS, Abdel-Aziz HA, Farrag NN, Youssef MM.

Eur J Med Chem. 2015 Jan 7;89:549-60. doi: 10.1016/j.ejmech.2014.10.064. Epub 2014 Oct 23.

PMID:
25462265

Supplemental Content

Support Center