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Items: 1 to 20 of 105

1.

Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's disease.

Zhang X, Tian Y, Li Z, Tian X, Sun H, Liu H, Moore A, Ran C.

J Am Chem Soc. 2013 Nov 6;135(44):16397-409. doi: 10.1021/ja405239v. Epub 2013 Oct 25.

2.

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease.

Zhang X, Tian Y, Zhang C, Tian X, Ross AW, Moir RD, Sun H, Tanzi RE, Moore A, Ran C.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9734-9. doi: 10.1073/pnas.1505420112. Epub 2015 Jul 21.

3.

A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease.

Zhang X, Tian Y, Yuan P, Li Y, Yaseen MA, Grutzendler J, Moore A, Ran C.

Chem Commun (Camb). 2014 Oct 9;50(78):11550-3. doi: 10.1039/c4cc03731f.

4.

Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer's disease.

Chen SY, Chen Y, Li YP, Chen SH, Tan JH, Ou TM, Gu LQ, Huang ZS.

Bioorg Med Chem. 2011 Sep 15;19(18):5596-604. doi: 10.1016/j.bmc.2011.07.033. Epub 2011 Jul 24.

PMID:
21840724
5.

Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits.

Ran C, Xu X, Raymond SB, Ferrara BJ, Neal K, Bacskai BJ, Medarova Z, Moore A.

J Am Chem Soc. 2009 Oct 28;131(42):15257-61. doi: 10.1021/ja9047043.

6.

A comparative study of dietary curcumin, nanocurcumin, and other classical amyloid-binding dyes for labeling and imaging of amyloid plaques in brain tissue of 5×-familial Alzheimer's disease mice.

Maiti P, Hall TC, Paladugu L, Kolli N, Learman C, Rossignol J, Dunbar GL.

Histochem Cell Biol. 2016 Nov;146(5):609-625. Epub 2016 Jul 12.

PMID:
27406082
7.

Amyloid-β Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation, and in Vivo Imaging.

Fu H, Tu P, Zhao L, Dai J, Liu B, Cui M.

Anal Chem. 2016 Feb 2;88(3):1944-50. doi: 10.1021/acs.analchem.5b04441. Epub 2016 Jan 12.

PMID:
26717442
8.

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.

Yang F, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambegaokar SS, Chen PP, Kayed R, Glabe CG, Frautschy SA, Cole GM.

J Biol Chem. 2005 Feb 18;280(7):5892-901. Epub 2004 Dec 7.

9.

Development of fluorescent probes that bind and stain amyloid plaques in Alzheimer's disease.

Jung SJ, Park SH, Lee EJ, Park JH, Kong YB, Rho JK, Hur MG, Yang SD, Park YD.

Arch Pharm Res. 2015 Nov;38(11):1992-8. doi: 10.1007/s12272-015-0617-4. Epub 2015 May 27.

PMID:
26012373
10.
11.

Design and synthesis of curcumin derivatives as tau and amyloid β dual aggregation inhibitors.

Okuda M, Hijikuro I, Fujita Y, Teruya T, Kawakami H, Takahashi T, Sugimoto H.

Bioorg Med Chem Lett. 2016 Oct 15;26(20):5024-5028. doi: 10.1016/j.bmcl.2016.08.092. Epub 2016 Aug 31.

PMID:
27624076
12.

Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta.

Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, Smith MA, Chen SG, Bush AI.

Biochemistry. 2004 Jan 20;43(2):560-8.

PMID:
14717612
13.

Fluorescent 2-styrylpyridazin-3(2H)-one derivatives as probes targeting amyloid-beta plaques in Alzheimer's disease.

Park YD, Park JH, Hur MG, Kim SW, Min JJ, Park SH, Yoo YJ, Yoon YJ, Yang SD.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):4106-10. doi: 10.1016/j.bmcl.2012.04.068. Epub 2012 Apr 21.

PMID:
22578456
14.

In vitro study on potential pharmacological activity of curcumin analogues and their copper complexes.

Ferrari E, Benassi R, Saladini M, Orteca G, Gazova Z, Siposova K.

Chem Biol Drug Des. 2017 Mar;89(3):411-419. doi: 10.1111/cbdd.12847. Epub 2016 Sep 23.

PMID:
27569739
15.

Smart near-infrared fluorescence probes with donor-acceptor structure for in vivo detection of β-amyloid deposits.

Cui M, Ono M, Watanabe H, Kimura H, Liu B, Saji H.

J Am Chem Soc. 2014 Mar 5;136(9):3388-94. doi: 10.1021/ja4052922. Epub 2014 Feb 20.

PMID:
24555862
16.

Inhibitory Activity Of Curcumin Derivatives Towards Metal-free And Metal-induced Amyloid-β Aggregation.

Kochi A, Lee HJ, Vithanarachchi SM, Padmini V, Allen MJ, Lim MH.

Curr Alzheimer Res. 2015;12(5):415-23.

PMID:
25938870
17.

Advances in development of fluorescent probes for detecting amyloid-β aggregates.

Xu MM, Ren WM, Tang XC, Hu YH, Zhang HY.

Acta Pharmacol Sin. 2016 Jun;37(6):719-30. doi: 10.1038/aps.2015.155. Epub 2016 Mar 21. Review.

18.

Curcuminoid binds to amyloid-β1-42 oligomer and fibril.

Yanagisawa D, Taguchi H, Yamamoto A, Shirai N, Hirao K, Tooyama I.

J Alzheimers Dis. 2011;24 Suppl 2:33-42. doi: 10.3233/JAD-2011-102100.

PMID:
21335654
19.

Syntheses And Evaluation Of Asymmetric Curcumin Analogues As Potential Multifunctional Agents For The Treatment Of Alzheimer's Disease.

Zhai P, Xia CL, Tan JH, Li D, Ou TM, Huang SL, Gu LQ, Huang ZS.

Curr Alzheimer Res. 2015;12(5):403-14.

PMID:
25938868
20.

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model.

Koronyo-Hamaoui M, Koronyo Y, Ljubimov AV, Miller CA, Ko MK, Black KL, Schwartz M, Farkas DL.

Neuroimage. 2011 Jan;54 Suppl 1:S204-17. doi: 10.1016/j.neuroimage.2010.06.020. Epub 2010 Jun 13.

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