Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 98

1.

A glutathione derivative with chelating and in vitro neuroprotective activities: synthesis, physicochemical properties, and biological evaluation.

Cacciatore I, Cornacchia C, Fornasari E, Baldassarre L, Pinnen F, Sozio P, Di Stefano A, Marinelli L, Dean A, Fulle S, Di Filippo ES, La Rovere RM, Patruno A, Ferrone A, Di Marco V.

ChemMedChem. 2013 Nov;8(11):1818-29. doi: 10.1002/cmdc.201300295. Epub 2013 Sep 17.

PMID:
24106097
2.

Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.

Fernández-Bachiller MI, Pérez C, González-Muñoz GC, Conde S, López MG, Villarroya M, García AG, Rodríguez-Franco MI.

J Med Chem. 2010 Jul 8;53(13):4927-37. doi: 10.1021/jm100329q.

PMID:
20545360
3.

New cyclodextrin-bearing 8-hydroxyquinoline ligands as multifunctional molecules.

Oliveri V, Puglisi A, Viale M, Aiello C, Sgarlata C, Vecchio G, Clarke J, Milton J, Spencer J.

Chemistry. 2013 Oct 4;19(41):13946-55. doi: 10.1002/chem.201300237. Epub 2013 Aug 22.

PMID:
24038335
5.

Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer's disease.

Rodríguez-Rodríguez C, Sánchez de Groot N, Rimola A, Alvarez-Larena A, Lloveras V, Vidal-Gancedo J, Ventura S, Vendrell J, Sodupe M, González-Duarte P.

J Am Chem Soc. 2009 Feb 4;131(4):1436-51. doi: 10.1021/ja806062g.

PMID:
19133767
6.

Preparation and study of new poly-8-hydroxyquinoline chelators for an anti-Alzheimer strategy.

Deraeve C, Boldron C, Maraval A, Mazarguil H, Gornitzka H, Vendier L, Pitié M, Meunier B.

Chemistry. 2008;14(2):682-96.

PMID:
17969218
7.

A Novel iron-chelating derivative of the neuroprotective peptide NAPVSIPQ shows superior antioxidant and antineurodegenerative capabilities.

Blat D, Weiner L, Youdim MB, Fridkin M.

J Med Chem. 2008 Jan 10;51(1):126-34. Epub 2007 Dec 14.

PMID:
18078312
8.

8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications.

Prachayasittikul V, Prachayasittikul S, Ruchirawat S, Prachayasittikul V.

Drug Des Devel Ther. 2013 Oct 4;7:1157-78. doi: 10.2147/DDDT.S49763. eCollection 2013. Review.

9.

Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress.

Chavarría C, Perez DI, Pérez C, Morales Garcia JA, Alonso-Gil S, Pérez-Castillo A, Gil C, Souza JM, Porcal W.

Eur J Med Chem. 2012 Dec;58:44-9. doi: 10.1016/j.ejmech.2012.09.044. Epub 2012 Oct 5.

PMID:
23085773
10.

Synthesis, physicochemical characterization, and biological activities of new carnosine derivatives stable in human serum as potential neuroprotective agents.

Bertinaria M, Rolando B, Giorgis M, Montanaro G, Guglielmo S, Buonsanti MF, Carabelli V, Gavello D, Daniele PG, Fruttero R, Gasco A.

J Med Chem. 2011 Jan 27;54(2):611-21. doi: 10.1021/jm101394n. Epub 2010 Dec 23.

PMID:
21182325
11.

Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway.

Mandel SA, Avramovich-Tirosh Y, Reznichenko L, Zheng H, Weinreb O, Amit T, Youdim MB.

Neurosignals. 2005;14(1-2):46-60. Review.

PMID:
15956814
12.

Advances in metal-induced oxidative stress and human disease.

Jomova K, Valko M.

Toxicology. 2011 May 10;283(2-3):65-87. doi: 10.1016/j.tox.2011.03.001. Epub 2011 Mar 23. Review.

PMID:
21414382
14.

Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity.

Zhu D, Chen M, Li M, Luo B, Zhao Y, Huang P, Xue F, Rapposelli S, Pi R, Wen S.

Eur J Med Chem. 2013 Oct;68:81-8. doi: 10.1016/j.ejmech.2013.07.029. Epub 2013 Aug 9.

PMID:
23973819
15.

Synthesis and structure-activity relationships study of dithiolethiones as inducers of glutathione in the SH-SY5Y neuroblastoma cell line.

Brown DA, Betharia S, Yen JH, Tran Q, Mistry H, Smith K.

Bioorg Med Chem Lett. 2014 Dec 15;24(24):5829-31. doi: 10.1016/j.bmcl.2014.10.005. Epub 2014 Oct 13.

PMID:
25455499
16.

Antioxidant properties and neuroprotective effects of isocampneoside II on hydrogen peroxide-induced oxidative injury in PC12 cells.

Si CL, Shen T, Jiang YY, Wu L, Yu GJ, Ren XD, Xu GH, Hu WC.

Food Chem Toxicol. 2013 Sep;59:145-52. doi: 10.1016/j.fct.2013.05.051. Epub 2013 Jun 11.

PMID:
23770344
17.

3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway.

Gunjima K, Tomiyama R, Takakura K, Yamada T, Hashida K, Nakamura Y, Konishi T, Matsugo S, Hori O.

J Cell Biochem. 2014 Jan;115(1):151-60. doi: 10.1002/jcb.24643.

PMID:
23959789
18.
19.

Manganese-induced oxidative DNA damage in neuronal SH-SY5Y cells: attenuation of thymine base lesions by glutathione and N-acetylcysteine.

Stephenson AP, Schneider JA, Nelson BC, Atha DH, Jain A, Soliman KF, Aschner M, Mazzio E, Renee Reams R.

Toxicol Lett. 2013 Apr 26;218(3):299-307. doi: 10.1016/j.toxlet.2012.12.024. Epub 2013 Jan 4.

20.

(R)-α-lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities.

Cacciatore I, Baldassarre L, Fornasari E, Cornacchia C, Di Stefano A, Sozio P, Cerasa LS, Fontana A, Fulle S, Di Filippo ES, La Rovere RM, Pinnen F.

ChemMedChem. 2012 Nov;7(11):2021-9. doi: 10.1002/cmdc.201200320. Epub 2012 Sep 13.

PMID:
22976949

Supplemental Content

Support Center