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Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor.

Burdach J, Funnell AP, Mak KS, Artuz CM, Wienert B, Lim WF, Tan LY, Pearson RC, Crossley M.

Nucleic Acids Res. 2014 Jan;42(1):276-89. doi: 10.1093/nar/gkt895. Epub 2013 Oct 7.


Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain.

Lim WF, Burdach J, Funnell AP, Pearson RC, Quinlan KG, Crossley M.

Nucleic Acids Res. 2016 Apr 20;44(7):3118-30. doi: 10.1093/nar/gkv1380. Epub 2015 Dec 15.


Identification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2).

Vasanth S, ZeRuth G, Kang HS, Jetten AM.

J Biol Chem. 2011 Feb 11;286(6):4749-59. doi: 10.1074/jbc.M110.165951. Epub 2010 Dec 2.


Structural Insights into c-Myc-interacting Zinc Finger Protein-1 (Miz-1) Delineate Domains Required for DNA Scanning and Sequence-specific Binding.

Bédard M, Roy V, Montagne M, Lavigne P.

J Biol Chem. 2017 Feb 24;292(8):3323-3340. doi: 10.1074/jbc.M116.748699. Epub 2016 Dec 29.


Engineered zinc-finger transcription factors activate OCT4 (POU5F1), SOX2, KLF4, c-MYC (MYC) and miR302/367.

Ji Q, Fischer AL, Brown CR, Eastlund ER, Dvash T, Zhong B, Gerber MA, Lyons I, Knight SW, Kreader CA.

Nucleic Acids Res. 2014 Jun;42(10):6158-67. doi: 10.1093/nar/gku243. Epub 2014 May 3.


Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability.

Gillinder KR, Ilsley MD, Nébor D, Sachidanandam R, Lajoie M, Magor GW, Tallack MR, Bailey T, Landsberg MJ, Mackay JP, Parker MW, Miles LA, Graber JH, Peters LL, Bieker JJ, Perkins AC.

Nucleic Acids Res. 2017 Feb 17;45(3):1130-1143. doi: 10.1093/nar/gkw1014.


Structural metal sites in nonclassical zinc finger proteins involved in transcriptional and translational regulation.

Lee SJ, Michel SL.

Acc Chem Res. 2014 Aug 19;47(8):2643-50. doi: 10.1021/ar500182d. Epub 2014 Aug 6.


Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Krüppel-like factor, a novel zinc finger repressor.

Uchida S, Tanaka Y, Ito H, Saitoh-Ohara F, Inazawa J, Yokoyama KK, Sasaki S, Marumo F.

Mol Cell Biol. 2000 Oct;20(19):7319-31.


A novel POK family transcription factor, ZBTB5, represses transcription of p21CIP1 gene.

Koh DI, Choi WI, Jeon BN, Lee CE, Yun CO, Hur MW.

J Biol Chem. 2009 Jul 24;284(30):19856-66. doi: 10.1074/jbc.M109.025817. Epub 2009 Jun 2.


Neutralizing the function of a β-globin-associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain.

Barrow JJ, Masannat J, Bungert J.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17948-53. doi: 10.1073/pnas.1207677109. Epub 2012 Oct 16.


The myeloid zinc finger gene, MZF-1, regulates the CD34 promoter in vitro.

Morris JF, Rauscher FJ 3rd, Davis B, Klemsz M, Xu D, Tenen D, Hromas R.

Blood. 1995 Nov 15;86(10):3640-7.


Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor.

Siatecka M, Sahr KE, Andersen SG, Mezei M, Bieker JJ, Peters LL.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15151-6. doi: 10.1073/pnas.1004996107. Epub 2010 Aug 9.


Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6 (KLF6) protein stability and tumor suppressor function.

Rodríguez E, Aburjania N, Priedigkeit NM, DiFeo A, Martignetti JA.

PLoS One. 2010 Sep 9;5(9). pii: e12639. doi: 10.1371/journal.pone.0012639.


Point mutations in BCL6 DNA-binding domain reveal distinct roles for the six zinc fingers.

Mascle X, Albagli O, Lemercier C.

Biochem Biophys Res Commun. 2003 Jan 10;300(2):391-6.


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