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Items: 1 to 20 of 124

1.

Perforin and granzymes work in synergy to mediate cholangiocyte injury in experimental biliary atresia.

Shivakumar P, Mourya R, Bezerra JA.

J Hepatol. 2014 Feb;60(2):370-6. doi: 10.1016/j.jhep.2013.09.021.

2.

Neonatal NK cells target the mouse duct epithelium via Nkg2d and drive tissue-specific injury in experimental biliary atresia.

Shivakumar P, Sabla GE, Whitington P, Chougnet CA, Bezerra JA.

J Clin Invest. 2009 Aug;119(8):2281-90.

3.

Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia.

Shivakumar P, Sabla G, Mohanty S, McNeal M, Ward R, Stringer K, Caldwell C, Chougnet C, Bezerra JA.

Gastroenterology. 2007 Jul;133(1):268-77.

4.

Extrahepatic cholangiocyte cilia are abnormal in biliary atresia.

Karjoo S, Hand NJ, Loarca L, Russo PA, Friedman JR, Wells RG.

J Pediatr Gastroenterol Nutr. 2013 Jul;57(1):96-101. doi: 10.1097/MPG.0b013e318296e525.

5.

Natural killer cells promote long-term hepatobiliary inflammation in a low-dose rotavirus model of experimental biliary atresia.

Squires JE, Shivakumar P, Mourya R, Bessho K, Walters S, Bezerra JA.

PLoS One. 2015 May 19;10(5):e0127191. doi: 10.1371/journal.pone.0127191.

6.
7.

Regulatory T cells inhibit Th1 cell-mediated bile duct injury in murine biliary atresia.

Tucker RM, Feldman AG, Fenner EK, Mack CL.

J Hepatol. 2013 Oct;59(4):790-6. doi: 10.1016/j.jhep.2013.05.010.

8.

Regulatory T cells control the CD8 adaptive immune response at the time of ductal obstruction in experimental biliary atresia.

Lages CS, Simmons J, Chougnet CA, Miethke AG.

Hepatology. 2012 Jul;56(1):219-27. doi: 10.1002/hep.25662.

9.

Rhesus rotavirus VP4 sequence-specific activation of mononuclear cells is associated with cholangiopathy in murine biliary atresia.

Walther A, Mohanty SK, Donnelly B, Coots A, Lages CS, Lobeck I, Dupree P, Meller J, McNeal M, Sestak K, Tiao G.

Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G466-74. doi: 10.1152/ajpgi.00079.2015. Erratum in: Am J Physiol Gastrointest Liver Physiol. 2016 Oct 1;311(4):G776.

10.

Rotavirus replication in the cholangiocyte mediates the temporal dependence of murine biliary atresia.

Mohanty SK, Donnelly B, Bondoc A, Jafri M, Walther A, Coots A, McNeal M, Witte D, Tiao GM.

PLoS One. 2013 Jul 3;8(7):e69069. doi: 10.1371/journal.pone.0069069.

11.

CD8+ T cells infiltrating into bile ducts in biliary atresia do not appear to function as cytotoxic T cells: a clinicopathological analysis.

Ahmed AF, Ohtani H, Nio M, Funaki N, Shimaoka S, Nagura H, Ohi R.

J Pathol. 2001 Mar;193(3):383-9.

PMID:
11241420
12.

Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype.

Li J, Bessho K, Shivakumar P, Mourya R, Mohanty SK, Dos Santos JL, Miura IK, Porta G, Bezerra JA.

J Clin Invest. 2011 Nov;121(11):4244-56. doi: 10.1172/JCI57728.

13.

Post-natal paucity of regulatory T cells and control of NK cell activation in experimental biliary atresia.

Miethke AG, Saxena V, Shivakumar P, Sabla GE, Simmons J, Chougnet CA.

J Hepatol. 2010 May;52(5):718-26. doi: 10.1016/j.jhep.2009.12.027.

14.

B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia.

Feldman AG, Tucker RM, Fenner EK, Pelanda R, Mack CL.

PLoS One. 2013 Aug 21;8(8):e73644. doi: 10.1371/journal.pone.0073644.

15.

Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia.

Shivakumar P, Campbell KM, Sabla GE, Miethke A, Tiao G, McNeal MM, Ward RL, Bezerra JA.

J Clin Invest. 2004 Aug;114(3):322-9.

16.

Cellular and humoral autoimmunity directed at bile duct epithelia in murine biliary atresia.

Mack CL, Tucker RM, Lu BR, Sokol RJ, Fontenot AP, Ueno Y, Gill RG.

Hepatology. 2006 Nov;44(5):1231-9.

17.

Combinatory effects of hepatic CD8+ and NK lymphocytes in bile duct injury from biliary atresia.

Guo C, Zhu J, Pu CL, Deng YH, Zhang MM.

Pediatr Res. 2012 Jun;71(6):638-44. doi: 10.1038/pr.2012.17.

PMID:
22476047
18.

Cholangiocyte expression of alpha2beta1-integrin confers susceptibility to rotavirus-induced experimental biliary atresia.

Jafri M, Donnelly B, Allen S, Bondoc A, McNeal M, Rennert PD, Weinreb PH, Ward R, Tiao G.

Am J Physiol Gastrointest Liver Physiol. 2008 Jul;295(1):G16-G26. doi: 10.1152/ajpgi.00442.2007.

19.

Role of myeloid differentiation factor 88 in Rhesus rotavirus-induced biliary atresia.

Walther AE, Mohanty SK, Donnelly B, Coots A, McNeal M, Tiao GM.

J Surg Res. 2013 Sep;184(1):322-9. doi: 10.1016/j.jss.2013.05.032.

20.

CD8+ T lymphocyte response against extrahepatic biliary epithelium is activated by epitopes within NSP4 in experimental biliary atresia.

Zheng S, Zhang H, Zhang X, Peng F, Chen X, Yang J, Brigstock D, Feng J.

Am J Physiol Gastrointest Liver Physiol. 2014 Jul 15;307(2):G233-40. doi: 10.1152/ajpgi.00099.2014.

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