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Items: 1 to 20 of 194

1.

A role for glutathione, independent of oxidative stress, in the developmental toxicity of methanol.

Siu MT, Shapiro AM, Wiley MJ, Wells PG.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):508-15. doi: 10.1016/j.taap.2013.09.020. Epub 2013 Oct 2.

PMID:
24095963
2.

Methanol exposure does not lead to accumulation of oxidative DNA damage in bone marrow and spleen of mice, rabbits or primates.

McCallum GP, Siu M, Ondovcik SL, Sweeting JN, Wells PG.

Mol Carcinog. 2011 Mar;50(3):163-72. doi: 10.1002/mc.20701. Epub 2010 Nov 23.

PMID:
21104990
3.

Methanol exposure does not produce oxidatively damaged DNA in lung, liver or kidney of adult mice, rabbits or primates.

McCallum GP, Siu M, Sweeting JN, Wells PG.

Toxicol Appl Pharmacol. 2011 Jan 15;250(2):147-53. doi: 10.1016/j.taap.2010.10.004. Epub 2010 Oct 13.

PMID:
20950637
4.

Enhanced NADPH oxidases and reactive oxygen species in the mechanism of methanol-initiated protein oxidation and embryopathies in vivo and in embryo culture.

Miller-Pinsler L, Sharma A, Wells PG.

Arch Toxicol. 2016 Mar;90(3):717-30. doi: 10.1007/s00204-015-1482-0. Epub 2015 Mar 1.

PMID:
25726414
7.

Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity.

Parman T, Wiley MJ, Wells PG.

Nat Med. 1999 May;5(5):582-5.

PMID:
10229238
9.

Subcellular compartmentalization of glutathione: correlations with parameters of oxidative stress related to genotoxicity.

Green RM, Graham M, O'Donovan MR, Chipman JK, Hodges NJ.

Mutagenesis. 2006 Nov;21(6):383-90. Epub 2006 Sep 29.

PMID:
17012304
10.

The free radical spin trapping agent phenylbutylnitrone reduces fetal brain DNA oxidation and postnatal cognitive deficits caused by in utero exposure to a non-structurally teratogenic dose of ethanol: a role for oxidative stress.

Miller L, Shapiro AM, Cheng J, Wells PG.

Free Radic Biol Med. 2013 Jul;60:223-32. doi: 10.1016/j.freeradbiomed.2013.02.015. Epub 2013 Feb 26. Erratum in: Free Radic Biol Med. 2013 Oct;63:368.

PMID:
23485582
12.

Methanol teratogenicity in mutant mice with deficient catalase activity and transgenic mice expressing human catalase.

Siu MT, Wiley MJ, Wells PG.

Reprod Toxicol. 2013 Apr;36:33-9. doi: 10.1016/j.reprotox.2012.11.006. Epub 2012 Dec 1.

PMID:
23207165
13.

Exposure to 5-bromo-2'-deoxyuridine induces oxidative stress and activator protein-1 DNA binding activity in the embryo.

Sahambi SK, Hales BF.

Birth Defects Res A Clin Mol Teratol. 2006 Aug;76(8):580-91.

PMID:
16955493
15.

Oxidative damage in chemical teratogenesis.

Wells PG, Kim PM, Laposa RR, Nicol CJ, Parman T, Winn LM.

Mutat Res. 1997 Dec 12;396(1-2):65-78. Review.

PMID:
9434860
16.
17.

Influence of dietary folic acid on the developmental toxicity of methanol and the frequency of chromosomal breakage in the CD-1 mouse.

Fu SS, Sakanashi TM, Rogers JM, Hong KH, Keen CL.

Reprod Toxicol. 1996 Nov-Dec;10(6):455-63.

PMID:
8946559
18.

Embryonic catalase protects against ethanol-initiated DNA oxidation and teratogenesis in acatalasemic and transgenic human catalase-expressing mice.

Miller L, Shapiro AM, Wells PG.

Toxicol Sci. 2013 Aug;134(2):400-11. doi: 10.1093/toxsci/kft122. Epub 2013 Jun 2.

PMID:
23733920
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20.

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