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Items: 1 to 20 of 148

1.

Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia.

Mosor M, Ziółkowska-Suchanek I, Nowicka K, Dzikiewicz-Krawczyk A, Januszkiewicz-Lewandowska D, Nowak J.

BMC Cancer. 2013 Oct 5;13:457. doi: 10.1186/1471-2407-13-457.

2.

Breast cancer risk is associated with the genes encoding the DNA double-strand break repair Mre11/Rad50/Nbs1 complex.

Hsu HM, Wang HC, Chen ST, Hsu GC, Shen CY, Yu JC.

Cancer Epidemiol Biomarkers Prev. 2007 Oct;16(10):2024-32.

3.

The MRN protein complex genes: MRE11 and RAD50 and susceptibility to head and neck cancers.

Ziółkowska-Suchanek I, Mosor M, Wierzbicka M, Rydzanicz M, Baranowska M, Nowak J.

Mol Cancer. 2013 Sep 30;12(1):113. doi: 10.1186/1476-4598-12-113.

4.

The importance of making ends meet: mutations in genes and altered expression of proteins of the MRN complex and cancer.

Dzikiewicz-Krawczyk A.

Mutat Res. 2008 Sep-Oct;659(3):262-73. doi: 10.1016/j.mrrev.2008.05.005. Epub 2008 Jun 23. Review.

PMID:
18606567
5.

Haplotypic variation in MRE11, RAD50 and NBS1 and risk of non-Hodgkin's lymphoma.

Rollinson S, Kesby H, Morgan GJ.

Leuk Lymphoma. 2006 Dec;47(12):2567-83.

PMID:
17169801
6.

Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study.

Damiola F, Pertesi M, Oliver J, Le Calvez-Kelm F, Voegele C, Young EL, Robinot N, Forey N, Durand G, Vallée MP, Tao K, Roane TC, Williams GJ, Hopper JL, Southey MC, Andrulis IL, John EM, Goldgar DE, Lesueur F, Tavtigian SV.

Breast Cancer Res. 2014 Jun 3;16(3):R58. doi: 10.1186/bcr3669.

7.
8.

The MRE11/RAD50/NBS1 complex destabilization in Lynch-syndrome patients.

Alemayehu A, Fridrichova I.

Eur J Hum Genet. 2007 Sep;15(9):922-9. Epub 2007 May 30.

9.

Functional polymorphisms in the NBS1 gene and acute lymphoblastic leukemia susceptibility in a Chinese population.

Jiang L, Liang J, Jiang M, Yu X, Zheng J, Liu H, Wu D, Zhou Y.

Eur J Haematol. 2011 Mar;86(3):199-205. doi: 10.1111/j.1600-0609.2010.01562.x. Epub 2011 Jan 25.

PMID:
21166880
10.

[Association between polymorphism of RAD50 gene and acute lymphoid leukemia in children].

Li W, Xu ZL.

Zhongguo Dang Dai Er Ke Za Zhi. 2015 May;17(5):469-71. Chinese.

11.

Breast cancer risk associated with genes encoding DNA repair MRN complex: a study from Punjab, Pakistan.

Khan RT, Siddique A, Shahid N, Khokher S, Fatima W.

Breast Cancer. 2018 May;25(3):350-355. doi: 10.1007/s12282-018-0837-9. Epub 2018 Jan 24.

PMID:
29368209
12.

Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene.

Bartkova J, Tommiska J, Oplustilova L, Aaltonen K, Tamminen A, Heikkinen T, Mistrik M, Aittomäki K, Blomqvist C, Heikkilä P, Lukas J, Nevanlinna H, Bartek J.

Mol Oncol. 2008 Dec;2(4):296-316. doi: 10.1016/j.molonc.2008.09.007. Epub 2008 Oct 7.

13.

Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation.

Mendez G, Cilli D, Berardinelli F, Viganotti M, Ascenzi P, Tanzarella C, Antoccia A, di Masi A.

IUBMB Life. 2012 Oct;64(10):853-61. doi: 10.1002/iub.1077. Epub 2012 Sep 3.

14.

RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability.

Heikkinen K, Rapakko K, Karppinen SM, Erkko H, Knuutila S, Lundán T, Mannermaa A, Børresen-Dale AL, Borg A, Barkardottir RB, Petrini J, Winqvist R.

Carcinogenesis. 2006 Aug;27(8):1593-9. Epub 2006 Feb 12.

15.

Frequency of pathogenic germline mutation in CHEK2, PALB2, MRE11, and RAD50 in patients at high risk for hereditary breast cancer.

Kim H, Cho DY, Choi DH, Oh M, Shin I, Park W, Huh SJ, Nam SJ, Lee JE, Kim SW.

Breast Cancer Res Treat. 2017 Jan;161(1):95-102. doi: 10.1007/s10549-016-4034-2. Epub 2016 Oct 25.

PMID:
27783279
16.

RAD50 and NBS1 are not likely to be susceptibility genes in Chinese non-BRCA1/2 hereditary breast cancer.

He M, Di GH, Cao AY, Hu Z, Jin W, Shen ZZ, Shao ZM.

Breast Cancer Res Treat. 2012 May;133(1):111-6. doi: 10.1007/s10549-011-1700-2. Epub 2011 Aug 3.

PMID:
21811815
17.

The germline variants in DNA repair genes in pediatric medulloblastoma: a challenge for current therapeutic strategies.

Trubicka J, Żemojtel T, Hecht J, Falana K, Piekutowska-Abramczuk D, Płoski R, Perek-Polnik M, Drogosiewicz M, Grajkowska W, Ciara E, Moszczyńska E, Dembowska-Bagińska B, Perek D, Chrzanowska KH, Krajewska-Walasek M, Łastowska M.

BMC Cancer. 2017 Apr 4;17(1):239. doi: 10.1186/s12885-017-3211-y.

18.

Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.

Lee JH, Ghirlando R, Bhaskara V, Hoffmeyer MR, Gu J, Paull TT.

J Biol Chem. 2003 Nov 14;278(46):45171-81. Epub 2003 Sep 8.

19.

Is the NBN gene mutation I171V a potential risk factor for malignant solid tumors in children?

Nowak J, Mosor M, Nowicka K, Rembowska J, Januszkiewicz D.

J Pediatr Hematol Oncol. 2011 Aug;33(6):e248-9. doi: 10.1097/MPH.0b013e3181faf886.

PMID:
21436738
20.

Heterozygous germ-line mutations in the NBN gene predispose to medulloblastoma in pediatric patients.

Ciara E, Piekutowska-Abramczuk D, Popowska E, Grajkowska W, Barszcz S, Perek D, Dembowska-Bagińska B, Perek-Polnik M, Kowalewska E, Czajńska A, Syczewska M, Czornak K, Krajewska-Walasek M, Roszkowski M, Chrzanowska KH.

Acta Neuropathol. 2010 Mar;119(3):325-34. doi: 10.1007/s00401-009-0608-y. Epub 2009 Nov 12.

PMID:
19908051

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