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Items: 1 to 20 of 83


2-Aminoadipic acid is a biomarker for diabetes risk.

Wang TJ, Ngo D, Psychogios N, Dejam A, Larson MG, Vasan RS, Ghorbani A, O'Sullivan J, Cheng S, Rhee EP, Sinha S, McCabe E, Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M, Pierce KA, Souza AL, Yu Y, Carter C, Light PE, Melander O, Clish CB, Gerszten RE.

J Clin Invest. 2013 Oct;123(10):4309-17. doi: 10.1172/JCI64801. Epub 2013 Sep 16.


Effect of chronic p,p'-dichlorodiphenyldichloroethylene (DDE) exposure on high fat diet-induced alterations in glucose and lipid metabolism in male C57BL/6H mice.

Howell GE 3rd, Mulligan C, Meek E, Chambers JE.

Toxicology. 2015 Feb 3;328:112-22. doi: 10.1016/j.tox.2014.12.017. Epub 2014 Dec 23.


Metabolite profiles and the risk of developing diabetes.

Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, Lewis GD, Fox CS, Jacques PF, Fernandez C, O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A, Melander O, Clish CB, Gerszten RE.

Nat Med. 2011 Apr;17(4):448-53. doi: 10.1038/nm.2307. Epub 2011 Mar 20.


High-fat diet induces early-onset diabetes in heterozygous Pax6 mutant mice.

Chen Y, Feng R, Wang H, Wei R, Yang J, Wang L, Wang H, Zhang L, Hong TP, Wen J.

Diabetes Metab Res Rev. 2014 Sep;30(6):467-75. doi: 10.1002/dmrr.2572.


SR-135, a peroxynitrite decomposing catalyst, enhances β-cell function and survival in B6D2F1 mice fed a high fat diet.

Johns M, Fyalka R, Shea JA, Neumann WL, Rausaria S, Msengi EN, Imani-Nejad M, Zollars H, McPherson T, Schober J, Wooten J, Kwon G.

Arch Biochem Biophys. 2015 Jul;577-578:49-59. doi: 10.1016/ Epub 2015 Apr 29.


Herring and Beef Meals Lead to Differences in Plasma 2-Aminoadipic Acid, β-Alanine, 4-Hydroxyproline, Cetoleic Acid, and Docosahexaenoic Acid Concentrations in Overweight Men.

Ross AB, Svelander C, Undeland I, Pinto R, Sandberg AS.

J Nutr. 2015 Nov;145(11):2456-63. doi: 10.3945/jn.115.214262. Epub 2015 Sep 23.


Impairment of pancreatic β-cell function by chronic intermittent hypoxia.

Wang N, Khan SA, Prabhakar NR, Nanduri J.

Exp Physiol. 2013 Sep;98(9):1376-85. doi: 10.1113/expphysiol.2013.072454. Epub 2013 May 24.


Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.

Wigger L, Cruciani-Guglielmacci C, Nicolas A, Denom J, Fernandez N, Fumeron F, Marques-Vidal P, Ktorza A, Kramer W, Schulte A, Le Stunff H, Liechti R, Xenarios I, Vollenweider P, Waeber G, Uphues I, Roussel R, Magnan C, Ibberson M, Thorens B.

Cell Rep. 2017 Feb 28;18(9):2269-2279. doi: 10.1016/j.celrep.2017.02.019.


Postprandial lipemia induces pancreatic α cell dysfunction characteristic of type 2 diabetes: studies in healthy subjects, mouse pancreatic islets, and cultured pancreatic α cells.

Niederwanger A, Ciardi C, Tatarczyk T, Khan MI, Hermann M, Mittermair C, Al-Zoairy R, Salzmann K, Pedrini MT.

Am J Clin Nutr. 2014 Nov;100(5):1222-31. doi: 10.3945/ajcn.114.092023. Epub 2014 Aug 20.


Metabolomics yield a novel biomarker for predicting diabetes mellitus risk in humans.

Arora P.

Circ Cardiovasc Genet. 2014 Feb;7(1):95-6. doi: 10.1161/CIRCGENETICS.114.000528. No abstract available.


TLR4 is required for the obesity-induced pancreatic beta cell dysfunction.

Li J, Chen L, Zhang Y, Zhang WJ, Xu W, Qin Y, Xu J, Zou D.

Acta Biochim Biophys Sin (Shanghai). 2013 Dec;45(12):1030-8. doi: 10.1093/abbs/gmt092. Epub 2013 Aug 28. Erratum in: Acta Biochim Biophys Sin (Shanghai). 2014 Feb;46(2):167.


Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance.

Usui M, Yamaguchi S, Tanji Y, Tominaga R, Ishigaki Y, Fukumoto M, Katagiri H, Mori K, Oka Y, Ishihara H.

Metabolism. 2012 Aug;61(8):1118-28. doi: 10.1016/j.metabol.2012.01.004. Epub 2012 Mar 3.


Insulin sensitivity and insulin secretion determined by homeostasis model assessment and risk of diabetes in a multiethnic cohort of women: the Women's Health Initiative Observational Study.

Song Y, Manson JE, Tinker L, Howard BV, Kuller LH, Nathan L, Rifai N, Liu S.

Diabetes Care. 2007 Jul;30(7):1747-52. Epub 2007 Apr 27.


Overexpression of peroxisome proliferator-activated receptor α in pancreatic β-cells improves glucose tolerance in diet-induced obese mice.

Hogh KL, Uy CE, Asadi A, Baker RK, Riedel MJ, Gray SL.

Exp Physiol. 2013 Feb;98(2):564-75. doi: 10.1113/expphysiol.2012.068734. Epub 2012 Oct 5.


Superior Glucose Tolerance and Metabolomic Profiles, Independent of Adiposity, in HIV-Infected Women Compared With Men on Antiretroviral Therapy.

Koethe JR, Jenkins CA, Petucci C, Culver J, Shepherd BE, Sterling TR.

Medicine (Baltimore). 2016 May;95(19):e3634. doi: 10.1097/MD.0000000000003634.


Serum preadipocyte factor 1 concentrations and risk of developing diabetes: a nested case-control study.

Lee SH, Rhee M, Yang HK, Ha HS, Lee JH, Kwon HS, Park YM, Yim HW, Kang MI, Lee WC, Son HY, Yoon KH.

Diabet Med. 2016 May;33(5):631-8. doi: 10.1111/dme.12871. Epub 2015 Oct 5.


Macrophage migration inhibitory factor deficiency protects pancreatic islets from palmitic acid-induced apoptosis.

Saksida T, Stosic-Grujicic S, Timotijevic G, Sandler S, Stojanovic I.

Immunol Cell Biol. 2012 Aug;90(7):688-98. doi: 10.1038/icb.2011.89. Epub 2011 Nov 8.


Dipeptidyl peptidase-4 inhibitor anagliptin ameliorates diabetes in mice with haploinsufficiency of glucokinase on a high-fat diet.

Nakaya K, Kubota N, Takamoto I, Kubota T, Katsuyama H, Sato H, Tokuyama K, Hashimoto S, Goto M, Jomori T, Ueki K, Kadowaki T.

Metabolism. 2013 Jul;62(7):939-51. doi: 10.1016/j.metabol.2013.01.010. Epub 2013 Feb 8.


Metabolite profiling identifies pathways associated with metabolic risk in humans.

Cheng S, Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D, Palma MJ, Roberts LD, Dejam A, Souza AL, Deik AA, Magnusson M, Fox CS, O'Donnell CJ, Vasan RS, Melander O, Clish CB, Gerszten RE, Wang TJ.

Circulation. 2012 May 8;125(18):2222-31. doi: 10.1161/CIRCULATIONAHA.111.067827. Epub 2012 Apr 11.


Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic beta-Cells and its role in promotion of insulin secretion and protection against diabetes.

Kobayashi M, Ohnishi H, Okazawa H, Murata Y, Hayashi Y, Kobayashi H, Kitamura T, Matozaki T.

Endocrinology. 2008 Nov;149(11):5662-9. doi: 10.1210/en.2008-0236. Epub 2008 Jul 17.


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