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Items: 1 to 20 of 100

1.

Effect of selectively introducing arginine and D-amino acids on the antimicrobial activity and salt sensitivity in analogs of human beta-defensins.

Olli S, Rangaraj N, Nagaraj R.

PLoS One. 2013 Sep 27;8(9):e77031. doi: 10.1371/journal.pone.0077031. eCollection 2013.

2.

Engineering of a linear inactive analog of human β-defensin 4 to generate peptides with potent antimicrobial activity.

Sharma H, Mathew B, Nagaraj R.

J Pept Sci. 2015 Jun;21(6):501-11. doi: 10.1002/psc.2770. Epub 2015 Mar 24.

PMID:
25810238
3.

Antibacterial activities of synthetic peptides corresponding to the carboxy-terminal region of human beta-defensins 1-3.

Krishnakumari V, Singh S, Nagaraj R.

Peptides. 2006 Nov;27(11):2607-13. Epub 2006 Jul 24.

PMID:
16860904
4.

Antimicrobial activity of human β-defensin 4 analogs: insights into the role of disulfide linkages in modulating activity.

Sharma H, Nagaraj R.

Peptides. 2012 Dec;38(2):255-65. doi: 10.1016/j.peptides.2012.08.024. Epub 2012 Sep 19.

PMID:
23000475
5.

Antifungal activities of human beta-defensins HBD-1 to HBD-3 and their C-terminal analogs Phd1 to Phd3.

Krishnakumari V, Rangaraj N, Nagaraj R.

Antimicrob Agents Chemother. 2009 Jan;53(1):256-60. doi: 10.1128/AAC.00470-08. Epub 2008 Sep 22.

6.

A hybrid cationic peptide composed of human β-defensin-1 and humanized θ-defensin sequences exhibits salt-resistant antimicrobial activity.

Olli S, Nagaraj R, Motukupally SR.

Antimicrob Agents Chemother. 2015 Jan;59(1):217-25. doi: 10.1128/AAC.03901-14. Epub 2014 Oct 27.

7.

Large-scale synthesis and functional elements for the antimicrobial activity of defensins.

Raj PA, Antonyraj KJ, Karunakaran T.

Biochem J. 2000 May 1;347 Pt 3:633-41.

8.

N-terminus three residues deletion mutant of human beta-defensin 3 with remarkably enhanced salt-resistance.

Li T, Guo F, Wang Q, Fang H, Li Z, Wang D, Wang H.

PLoS One. 2015 Feb 23;10(2):e0117913. doi: 10.1371/journal.pone.0117913. eCollection 2015.

9.
10.

Human β-defensin 4 with non-native disulfide bridges exhibit antimicrobial activity.

Sharma H, Nagaraj R.

PLoS One. 2015 Mar 18;10(3):e0119525. doi: 10.1371/journal.pone.0119525. eCollection 2015.

11.

Novel synthetic, salt-resistant analogs of human beta-defensins 1 and 3 endowed with enhanced antimicrobial activity.

Scudiero O, Galdiero S, Cantisani M, Di Noto R, Vitiello M, Galdiero M, Naclerio G, Cassiman JJ, Pedone C, Castaldo G, Salvatore F.

Antimicrob Agents Chemother. 2010 Jun;54(6):2312-22. doi: 10.1128/AAC.01550-09. Epub 2010 Mar 22.

12.

N-Terminal fatty acylation of peptides spanning the cationic C-terminal segment of bovine β-defensin-2 results in salt-resistant antibacterial activity.

Krishnakumari V, Nagaraj R.

Biophys Chem. 2015 Apr;199:25-33. doi: 10.1016/j.bpc.2015.02.005. Epub 2015 Feb 20.

PMID:
25791057
13.

Human beta-defensin-3: a promising antimicrobial peptide.

Batoni G, Maisetta G, Esin S, Campa M.

Mini Rev Med Chem. 2006 Oct;6(10):1063-73. Review.

PMID:
17073706
14.

Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3.

Wu Z, Hoover DM, Yang D, Boulègue C, Santamaria F, Oppenheim JJ, Lubkowski J, Lu W.

Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8880-5. Epub 2003 Jul 2.

15.

Influence of truncation of avian β-defensin-4 on biological activity and peptide-membrane interaction.

Dong N, Ma QQ, Shan AS, Wang L, Sun WY, Li YZ.

Protein Pept Lett. 2012 Apr;19(4):430-8.

PMID:
22316306
16.

Antimicrobial characterization of human beta-defensin 3 derivatives.

Hoover DM, Wu Z, Tucker K, Lu W, Lubkowski J.

Antimicrob Agents Chemother. 2003 Sep;47(9):2804-9.

17.

Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs.

Zou G, de Leeuw E, Li C, Pazgier M, Li C, Zeng P, Lu WY, Lubkowski J, Lu W.

J Biol Chem. 2007 Jul 6;282(27):19653-65. Epub 2007 Apr 23.

18.

Structure-activity relation of human beta-defensin 3: influence of disulfide bonds and cysteine substitution on antimicrobial activity and cytotoxicity.

Klüver E, Schulz-Maronde S, Scheid S, Meyer B, Forssmann WG, Adermann K.

Biochemistry. 2005 Jul 19;44(28):9804-16.

PMID:
16008365
20.

Antimicrobial activity of human α-defensin 6 analogs: insights into the physico-chemical reasons behind weak bactericidal activity of HD6 in vitro.

Mathew B, Nagaraj R.

J Pept Sci. 2015 Nov;21(11):811-8. doi: 10.1002/psc.2821. Epub 2015 Sep 24.

PMID:
26400692

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