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Items: 1 to 20 of 132

1.

Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.

Åhsberg J, Ungerbäck J, Strid T, Welinder E, Stjernberg J, Larsson M, Qian H, Sigvardsson M.

J Biol Chem. 2013 Nov 15;288(46):33449-61. doi: 10.1074/jbc.M113.506261. Epub 2013 Sep 27.

2.

A dose-dependent role for EBF1 in repressing non-B-cell-specific genes.

Lukin K, Fields S, Guerrettaz L, Straign D, Rodriguez V, Zandi S, Månsson R, Cambier JC, Sigvardsson M, Hagman J.

Eur J Immunol. 2011 Jun;41(6):1787-93. doi: 10.1002/eji.201041137. Epub 2011 May 9.

3.

Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency.

Prasad MA, Ungerbäck J, Åhsberg J, Somasundaram R, Strid T, Larsson M, Månsson R, De Paepe A, Lilljebjörn H, Fioretos T, Hagman J, Sigvardsson M.

Blood. 2015 Jun 25;125(26):4052-9. doi: 10.1182/blood-2014-12-617282. Epub 2015 Apr 2.

4.

Combined heterozygous loss of Ebf1 and Pax5 allows for T-lineage conversion of B cell progenitors.

Ungerbäck J, Åhsberg J, Strid T, Somasundaram R, Sigvardsson M.

J Exp Med. 2015 Jun 29;212(7):1109-23. doi: 10.1084/jem.20132100. Epub 2015 Jun 8.

5.

Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia.

Heltemes-Harris LM, Willette MJ, Ramsey LB, Qiu YH, Neeley ES, Zhang N, Thomas DA, Koeuth T, Baechler EC, Kornblau SM, Farrar MA.

J Exp Med. 2011 Jun 6;208(6):1135-49. doi: 10.1084/jem.20101947. Epub 2011 May 23.

6.

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development.

Kwon K, Hutter C, Sun Q, Bilic I, Cobaleda C, Malin S, Busslinger M.

Immunity. 2008 Jun;28(6):751-62. doi: 10.1016/j.immuni.2008.04.014.

7.

The SWI/SNF-like BAF complex is essential for early B cell development.

Choi J, Ko M, Jeon S, Jeon Y, Park K, Lee C, Lee H, Seong RH.

J Immunol. 2012 Apr 15;188(8):3791-803. doi: 10.4049/jimmunol.1103390. Epub 2012 Mar 16.

8.

IRF8 regulates B-cell lineage specification, commitment, and differentiation.

Wang H, Lee CH, Qi C, Tailor P, Feng J, Abbasi S, Atsumi T, Morse HC 3rd.

Blood. 2008 Nov 15;112(10):4028-38. doi: 10.1182/blood-2008-01-129049. Epub 2008 Sep 17.

9.

EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors.

Zandi S, Mansson R, Tsapogas P, Zetterblad J, Bryder D, Sigvardsson M.

J Immunol. 2008 Sep 1;181(5):3364-72.

10.

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.

Lin YC, Jhunjhunwala S, Benner C, Heinz S, Welinder E, Mansson R, Sigvardsson M, Hagman J, Espinoza CA, Dutkowski J, Ideker T, Glass CK, Murre C.

Nat Immunol. 2010 Jul;11(7):635-43. doi: 10.1038/ni.1891. Epub 2010 Jun 13.

11.

Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5.

Roessler S, Györy I, Imhof S, Spivakov M, Williams RR, Busslinger M, Fisher AG, Grosschedl R.

Mol Cell Biol. 2007 Jan;27(2):579-94. Epub 2006 Nov 13.

12.

Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression.

Lukin K, Fields S, Lopez D, Cherrier M, Ternyak K, Ramírez J, Feeney AJ, Hagman J.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7869-74. doi: 10.1073/pnas.1003525107. Epub 2010 Apr 12.

13.
14.

Allelic exclusion of IgH through inhibition of E2A in a VDJ recombination complex.

Hauser J, Grundström C, Grundström T.

J Immunol. 2014 Mar 1;192(5):2460-70. doi: 10.4049/jimmunol.1302216. Epub 2014 Jan 27.

15.

Context-dependent regulation of hematopoietic lineage choice by HEBAlt.

Wang D, Claus CL, Rajkumar P, Braunstein M, Moore AJ, Sigvardsson M, Anderson MK.

J Immunol. 2010 Oct 1;185(7):4109-17. doi: 10.4049/jimmunol.0901783. Epub 2010 Sep 8.

16.

Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo.

Zandi S, Ahsberg J, Tsapogas P, Stjernberg J, Qian H, Sigvardsson M.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15871-6. Epub 2012 Sep 10.

17.

PAX5 promotes pre-B cell proliferation by regulating the expression of pre-B cell receptor and its downstream signaling.

Xue K, Song J, Yang Y, Li Z, Wu C, Jin J, Li W.

Mol Immunol. 2016 May;73:1-9. doi: 10.1016/j.molimm.2016.03.007. Epub 2016 Mar 24.

PMID:
27016671
18.

Ebf1-mediated down-regulation of Id2 and Id3 is essential for specification of the B cell lineage.

Thal MA, Carvalho TL, He T, Kim HG, Gao H, Hagman J, Klug CA.

Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):552-7. doi: 10.1073/pnas.0802550106. Epub 2009 Jan 2.

19.

Immunologic regulation of bone development.

Horowitz MC, Lorenzo JA.

Adv Exp Med Biol. 2007;602:47-56.

PMID:
17966387
20.

Biphenotypic B-lymphoid/myeloid cells expressing low levels of Pax5: potential targets of BAL development.

Simmons S, Knoll M, Drewell C, Wolf I, Mollenkopf HJ, Bouquet C, Melchers F.

Blood. 2012 Nov 1;120(18):3688-98. doi: 10.1182/blood-2012-03-414821. Epub 2012 Aug 27.

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