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Items: 1 to 20 of 112

1.

Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway.

Zhang H, Tan S, Wang J, Chen S, Quan J, Xian J, Zhang Ss, He J, Zhang L.

Exp Cell Res. 2014 Jan 1;320(1):119-27. doi: 10.1016/j.yexcr.2013.09.009. Epub 2013 Sep 26.

PMID:
24076374
2.

Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin.

Han Y, Ye A, Zhang Y, Cai Z, Wang W, Sun L, Jiang S, Wu J, Yu K, Zhang S.

PLoS One. 2015 Aug 26;10(8):e0136484. doi: 10.1371/journal.pone.0136484. eCollection 2015.

3.

The inhibition of ERK/MAPK not the activation of JNK/SAPK is primarily required to induce apoptosis in chronic myelogenous leukemic K562 cells.

Kang CD, Yoo SD, Hwang BW, Kim KW, Kim DW, Kim CM, Kim SH, Chung BS.

Leuk Res. 2000 Jun;24(6):527-34.

PMID:
10781688
6.

Anti-leukemic effect of 2-pyrone derivatives via MAPK and PI3 kinase pathways.

Yoon JS, Won YW, Kim SJ, Oh SJ, Kim ES, Kim BK, Cho CG, Choi JH, Park BB, Lee MH, Lee YY.

Invest New Drugs. 2012 Dec;30(6):2284-93. doi: 10.1007/s10637-012-9814-x. Epub 2012 Apr 19.

PMID:
22526834
7.

Betuletol 3-methyl ether induces G(2)-M phase arrest and activates the sphingomyelin and MAPK pathways in human leukemia cells.

Rubio S, Quintana J, Eiroa JL, Triana J, Estévez F.

Mol Carcinog. 2010 Jan;49(1):32-43. doi: 10.1002/mc.20574.

PMID:
19676104
8.

Helicobacter pylori and mitogen-activated protein kinases regulate the cell cycle, proliferation and apoptosis in gastric epithelial cells.

Ding SZ, Smith MF Jr, Goldberg JB.

J Gastroenterol Hepatol. 2008 Jul;23(7 Pt 2):e67-78. doi: 10.1111/j.1440-1746.2007.04912.x.

PMID:
18702686
9.

Aggressive myeloid leukemia formation is directed by the Musashi 2/Numb pathway.

Griner LN, Reuther GW.

Cancer Biol Ther. 2010 Nov 15;10(10):979-82. Epub 2010 Nov 15.

PMID:
21084860
10.

Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway.

Vaqué JP, Navascues J, Shiio Y, Laiho M, Ajenjo N, Mauleon I, Matallanas D, Crespo P, León J.

J Biol Chem. 2005 Jan 14;280(2):1112-22. Epub 2004 Nov 4.

11.

Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.

Park SM, Gönen M, Vu L, Minuesa G, Tivnan P, Barlowe TS, Taggart J, Lu Y, Deering RP, Hacohen N, Figueroa ME, Paietta E, Fernandez HF, Tallman MS, Melnick A, Levine R, Leslie C, Lengner CJ, Kharas MG.

J Clin Invest. 2015 Mar 2;125(3):1286-98. doi: 10.1172/JCI78440. Epub 2015 Feb 9.

12.
13.

Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt.

Moon DO, Park SY, Heo MS, Kim KC, Park C, Ko WS, Choi YH, Kim GY.

Int Immunopharmacol. 2006 Dec 5;6(12):1796-807. Epub 2006 Aug 22.

PMID:
17052670
14.

Inhibition of MEK signaling enhances the ability of cytarabine to induce growth arrest and apoptosis of acute myelogenous leukemia cells.

Nishioka C, Ikezoe T, Yang J, Yokoyama A.

Apoptosis. 2009 Sep;14(9):1108-20. doi: 10.1007/s10495-009-0372-4.

PMID:
19548087
15.

Dynamic transcriptomes of human myeloid leukemia cells.

Wang H, Hu H, Zhang Q, Yang Y, Li Y, Hu Y, Ruan X, Yang Y, Zhang Z, Shu C, Yan J, Wakeland EK, Li Q, Hu S, Fang X.

Genomics. 2013 Oct;102(4):250-6. doi: 10.1016/j.ygeno.2013.06.004. Epub 2013 Jun 24.

PMID:
23806289
16.

Different roles of p38 MAPK and ERK in STI571-induced multi-lineage differentiation of K562 cells.

Kohmura K, Miyakawa Y, Kawai Y, Ikeda Y, Kizaki M.

J Cell Physiol. 2004 Mar;198(3):370-6.

PMID:
14755542
17.

Regulation of Bcl2 phosphorylation and potential significance for leukemic cell chemoresistance.

Deng X, Kornblau SM, Ruvolo PP, May WS Jr.

J Natl Cancer Inst Monogr. 2001;(28):30-7. Review.

PMID:
11158204
19.

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia.

Kharas MG, Lengner CJ, Al-Shahrour F, Bullinger L, Ball B, Zaidi S, Morgan K, Tam W, Paktinat M, Okabe R, Gozo M, Einhorn W, Lane SW, Scholl C, Fröhling S, Fleming M, Ebert BL, Gilliland DG, Jaenisch R, Daley GQ.

Nat Med. 2010 Aug;16(8):903-8. doi: 10.1038/nm.2187. Epub 2010 Jul 8.

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