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Items: 1 to 20 of 265

1.

Delta-like ligand 4 regulates vascular endothelial growth factor receptor 2-driven luteal angiogenesis through induction of a tip/stalk phenotype in proliferating endothelial cells.

García-Pascual CM, Zimmermann RC, Ferrero H, Shawber CJ, Kitajewski J, Simón C, Pellicer A, Gómez R.

Fertil Steril. 2013 Dec;100(6):1768-76.e1. doi: 10.1016/j.fertnstert.2013.08.034. Epub 2013 Sep 26.

PMID:
24074756
2.

Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis.

Adam MG, Berger C, Feldner A, Yang WJ, Wüstehube-Lausch J, Herberich SE, Pinder M, Gesierich S, Hammes HP, Augustin HG, Fischer A.

Circ Res. 2013 Nov 8;113(11):1206-18. doi: 10.1161/CIRCRESAHA.113.301686. Epub 2013 Sep 11.

3.

MOSAIC: a multiscale model of osteogenesis and sprouting angiogenesis with lateral inhibition of endothelial cells.

Carlier A, Geris L, Bentley K, Carmeliet G, Carmeliet P, Van Oosterwyck H.

PLoS Comput Biol. 2012;8(10):e1002724. doi: 10.1371/journal.pcbi.1002724. Epub 2012 Oct 11. Erratum in: PLoS Comput Biol. 2013 Mar;9(3). doi: 10.1371/annotation/38264a13-d4b5-49cd-b54e-47330bb19fe9.

4.

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.

Hellström M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalén M, Gerhardt H, Betsholtz C.

Nature. 2007 Feb 15;445(7129):776-80. Epub 2007 Jan 28.

PMID:
17259973
5.

Inhibition of Delta-like 4 mediated signaling induces abortion in mice due to deregulation of decidual angiogenesis.

García-Pascual CM, Ferrero H, Zimmermann RC, Simón C, Pellicer A, Gómez R.

Placenta. 2014 Jul;35(7):501-8. doi: 10.1016/j.placenta.2014.03.019. Epub 2014 Apr 15.

PMID:
24780197
6.

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

Suchting S, Freitas C, le Noble F, Benedito R, Bréant C, Duarte A, Eichmann A.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3225-30. Epub 2007 Feb 12.

7.

The Dll4/Notch pathway controls postangiogenic blood vessel remodeling and regression by modulating vasoconstriction and blood flow.

Lobov IB, Cheung E, Wudali R, Cao J, Halasz G, Wei Y, Economides A, Lin HC, Papadopoulos N, Yancopoulos GD, Wiegand SJ.

Blood. 2011 Jun 16;117(24):6728-37. doi: 10.1182/blood-2010-08-302067. Epub 2011 Apr 15.

8.

Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis.

Liu ZJ, Shirakawa T, Li Y, Soma A, Oka M, Dotto GP, Fairman RM, Velazquez OC, Herlyn M.

Mol Cell Biol. 2003 Jan;23(1):14-25.

9.

Notch pathway targets proangiogenic regulator Sox17 to restrict angiogenesis.

Lee SH, Lee S, Yang H, Song S, Kim K, Saunders TL, Yoon JK, Koh GY, Kim I.

Circ Res. 2014 Jul 7;115(2):215-26. doi: 10.1161/CIRCRESAHA.115.303142. Epub 2014 Apr 22.

10.

Cross-talk between leukemic and endothelial cells promotes angiogenesis by VEGF activation of the Notch/Dll4 pathway.

Zhang J, Ye J, Ma D, Liu N, Wu H, Yu S, Sun X, Tse W, Ji C.

Carcinogenesis. 2013 Mar;34(3):667-77. doi: 10.1093/carcin/bgs386. Epub 2012 Dec 13.

PMID:
23239744
11.

MEDI0639: a novel therapeutic antibody targeting Dll4 modulates endothelial cell function and angiogenesis in vivo.

Jenkins DW, Ross S, Veldman-Jones M, Foltz IN, Clavette BC, Manchulenko K, Eberlein C, Kendrew J, Petteruti P, Cho S, Damschroder M, Peng L, Baker D, Smith NR, Weir HM, Blakey DC, Bedian V, Barry ST.

Mol Cancer Ther. 2012 Aug;11(8):1650-60. doi: 10.1158/1535-7163.MCT-11-1027. Epub 2012 Jun 7.

12.

Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4/Notch1.

Pedrosa AR, Trindade A, Fernandes AC, Carvalho C, Gigante J, Tavares AT, Diéguez-Hurtado R, Yagita H, Adams RH, Duarte A.

Arterioscler Thromb Vasc Biol. 2015 May;35(5):1134-46. doi: 10.1161/ATVBAHA.114.304741. Epub 2015 Mar 12.

13.

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.

Pitulescu ME, Schmidt I, Giaimo BD, Antoine T, Berkenfeld F, Ferrante F, Park H, Ehling M, Biljes D, Rocha SF, Langen UH, Stehling M, Nagasawa T, Ferrara N, Borggrefe T, Adams RH.

Nat Cell Biol. 2017 Aug;19(8):915-927. doi: 10.1038/ncb3555. Epub 2017 Jul 17.

PMID:
28714968
14.

Laminin-binding integrins induce Dll4 expression and Notch signaling in endothelial cells.

Estrach S, Cailleteau L, Franco CA, Gerhardt H, Stefani C, Lemichez E, Gagnoux-Palacios L, Meneguzzi G, Mettouchi A.

Circ Res. 2011 Jul 8;109(2):172-82. doi: 10.1161/CIRCRESAHA.111.240622. Epub 2011 Apr 7.

15.

VEGFRs and Notch: a dynamic collaboration in vascular patterning.

Jakobsson L, Bentley K, Gerhardt H.

Biochem Soc Trans. 2009 Dec;37(Pt 6):1233-6. doi: 10.1042/BST0371233. Review.

PMID:
19909253
16.

Inhibition of delta-like ligand 4 induces luteal hypervascularization followed by functional and structural luteolysis in the primate ovary.

Fraser HM, Hastings JM, Allan D, Morris KD, Rudge JS, Wiegand SJ.

Endocrinology. 2012 Apr;153(4):1972-83. doi: 10.1210/en.2011-1688. Epub 2012 Feb 14.

17.

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes.

Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CE, Leek R, Edelmann M, Kessler B, Sainson RC, Sargent I, Li JL, Harris AL.

Blood. 2010 Sep 30;116(13):2385-94. doi: 10.1182/blood-2009-08-239228. Epub 2010 Jun 17.

18.

Angiogenic morphogenesis driven by dynamic and heterogeneous collective endothelial cell movement.

Arima S, Nishiyama K, Ko T, Arima Y, Hakozaki Y, Sugihara K, Koseki H, Uchijima Y, Kurihara Y, Kurihara H.

Development. 2011 Nov;138(21):4763-76. doi: 10.1242/dev.068023. Epub 2011 Sep 28.

19.

Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism.

Kim J, Oh WJ, Gaiano N, Yoshida Y, Gu C.

Genes Dev. 2011 Jul 1;25(13):1399-411. doi: 10.1101/gad.2042011.

20.

Negative regulators of vessel patterning.

Suchting S, Freitas C, le Noble F, Benedito R, Bréant C, Duarte A, Eichmann A.

Novartis Found Symp. 2007;283:77-80; discussion 80-6, 238-41.

PMID:
18300415

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