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Highly pathogenic avian influenza virus nucleoprotein interacts with TREX complex adaptor protein Aly/REF.

Balasubramaniam VR, Hong Wai T, Ario Tejo B, Omar AR, Syed Hassan S.

PLoS One. 2013 Sep 20;8(9):e72429. doi: 10.1371/journal.pone.0072429. eCollection 2013.


The interaction of the cellular export adaptor protein Aly/REF with ICP27 contributes to the efficiency of herpes simplex virus 1 mRNA export.

Tian X, Devi-Rao G, Golovanov AP, Sandri-Goldin RM.

J Virol. 2013 Jul;87(13):7210-7. doi: 10.1128/JVI.00738-13. Epub 2013 May 1.


ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56.

Taniguchi I, Ohno M.

Mol Cell Biol. 2008 Jan;28(2):601-8. Epub 2007 Nov 5.


Effective small interfering RNAs targeting matrix and nucleocapsid protein gene inhibit influenza A virus replication in cells and mice.

Zhou H, Jin M, Yu Z, Xu X, Peng Y, Wu H, Liu J, Liu H, Cao S, Chen H.

Antiviral Res. 2007 Nov;76(2):186-93. Epub 2007 Aug 10.


Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins.

Bortz E, Westera L, Maamary J, Steel J, Albrecht RA, Manicassamy B, Chase G, Martínez-Sobrido L, Schwemmle M, García-Sastre A.

MBio. 2011 Aug 16;2(4). pii: e00151-11. doi: 10.1128/mBio.00151-11. Print 2011.


Aly/ REF, a factor for mRNA transport, activates RH gene promoter function.

Suganuma H, Kumada M, Omi T, Gotoh T, Lkhagvasuren M, Okuda H, Kamesaki T, Kajii E, Iwamoto S.

FEBS J. 2005 Jun;272(11):2696-704.


Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export.

Read EK, Digard P.

J Gen Virol. 2010 May;91(Pt 5):1290-301. doi: 10.1099/vir.0.018564-0. Epub 2010 Jan 13.


Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy.

Stubbs SH, Conrad NK.

Nucleic Acids Res. 2015 Jan;43(1):504-19. doi: 10.1093/nar/gku1278. Epub 2014 Dec 3.


Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA.

Chi B, Wang Q, Wu G, Tan M, Wang L, Shi M, Chang X, Cheng H.

Nucleic Acids Res. 2013 Jan;41(2):1294-306. doi: 10.1093/nar/gks1188. Epub 2012 Dec 7.


Influenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activation.

Sharma K, Tripathi S, Ranjan P, Kumar P, Garten R, Deyde V, Katz JM, Cox NJ, Lal RB, Sambhara S, Lal SK.

PLoS One. 2011;6(6):e20215. doi: 10.1371/journal.pone.0020215. Epub 2011 Jun 15.


The viral nucleoprotein determines Mx sensitivity of influenza A viruses.

Zimmermann P, Mänz B, Haller O, Schwemmle M, Kochs G.

J Virol. 2011 Aug;85(16):8133-40. doi: 10.1128/JVI.00712-11. Epub 2011 Jun 15.


SR proteins SRp20 and 9G8 contribute to efficient export of herpes simplex virus 1 mRNAs.

Escudero-Paunetto L, Li L, Hernandez FP, Sandri-Goldin RM.

Virology. 2010 Jun 5;401(2):155-64. doi: 10.1016/j.virol.2010.02.023. Epub 2010 Mar 12.


Characteristics of nucleocytoplasmic transport of H1N1 influenza A virus nuclear export protein.

Gao S, Wang S, Cao S, Sun L, Li J, Bi Y, Gao GF, Liu W.

J Virol. 2014 Jul;88(13):7455-63. doi: 10.1128/JVI.00257-14. Epub 2014 Apr 16.


Nuclear factor 90 negatively regulates influenza virus replication by interacting with viral nucleoprotein.

Wang P, Song W, Mok BW, Zhao P, Qin K, Lai A, Smith GJ, Zhang J, Lin T, Guan Y, Chen H.

J Virol. 2009 Aug;83(16):7850-61. doi: 10.1128/JVI.00735-09. Epub 2009 Jun 3.


Evolutionary dynamics of influenza A nucleoprotein (NP) lineages revealed by large-scale sequence analyses.

Xu J, Christman MC, Donis RO, Lu G.

Infect Genet Evol. 2011 Dec;11(8):2125-32. doi: 10.1016/j.meegid.2011.07.002. Epub 2011 Jul 7.


The role of the N-terminal caspase cleavage site in the nucleoprotein of influenza A virus in vitro and in vivo.

Lipatov AS, Yen HL, Salomon R, Ozaki H, Hoffmann E, Webster RG.

Arch Virol. 2008;153(3):427-34. Epub 2007 Dec 4.


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