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Items: 1 to 20 of 109


Sonic hedgehog mediates the proliferation and recruitment of transformed mesenchymal stem cells to the stomach.

Donnelly JM, Chawla A, Houghton J, Zavros Y.

PLoS One. 2013 Sep 19;8(9):e75225. doi: 10.1371/journal.pone.0075225. eCollection 2013.


Mesenchymal stem cells induce epithelial proliferation within the inflamed stomach.

Donnelly JM, Engevik A, Feng R, Xiao C, Boivin GP, Li J, Houghton J, Zavros Y.

Am J Physiol Gastrointest Liver Physiol. 2014 Jun 15;306(12):G1075-88. doi: 10.1152/ajpgi.00489.2012. Epub 2014 May 1.


The role of sonic hedgehog reemergence during gastric cancer.

Martin J, Donnelly JM, Houghton J, Zavros Y.

Dig Dis Sci. 2010 Jun;55(6):1516-24. doi: 10.1007/s10620-010-1252-z. Epub 2010 May 1. Review.


Gastritis promotes an activated bone marrow-derived mesenchymal stem cell with a phenotype reminiscent of a cancer-promoting cell.

Donnelly JM, Engevik AC, Engevik M, Schumacher MA, Xiao C, Yang L, Worrell RT, Zavros Y.

Dig Dis Sci. 2014 Mar;59(3):569-82. doi: 10.1007/s10620-013-2927-z. Epub 2013 Nov 8.


Indian Hedgehog mediates gastrin-induced proliferation in stomach of adult mice.

Feng R, Aihara E, Kenny S, Yang L, Li J, Varro A, Montrose MH, Shroyer NF, Wang TC, Shivdasani RA, Zavros Y.

Gastroenterology. 2014 Sep;147(3):655-666.e9. doi: 10.1053/j.gastro.2014.05.006. Epub 2014 May 20.


Multipotent mesenchymal stromal cells increase tPA expression and concomitantly decrease PAI-1 expression in astrocytes through the sonic hedgehog signaling pathway after stroke (in vitro study).

Xin H, Li Y, Shen LH, Liu X, Hozeska-Solgot A, Zhang RL, Zhang ZG, Chopp M.

J Cereb Blood Flow Metab. 2011 Nov;31(11):2181-8. doi: 10.1038/jcbfm.2011.116. Epub 2011 Aug 10.


The acid-secreting parietal cell as an endocrine source of Sonic Hedgehog during gastric repair.

Engevik AC, Feng R, Yang L, Zavros Y.

Endocrinology. 2013 Dec;154(12):4627-39. doi: 10.1210/en.2013-1483. Epub 2013 Oct 3.


Interleukin-1beta promotes gastric atrophy through suppression of Sonic Hedgehog.

Waghray M, Zavros Y, Saqui-Salces M, El-Zaatari M, Alamelumangapuram CB, Todisco A, Eaton KA, Merchant JL.

Gastroenterology. 2010 Feb;138(2):562-72, 572.e1-2. doi: 10.1053/j.gastro.2009.10.043. Epub 2009 Oct 31.


Hedgehog-mediated paracrine interaction between hepatic stellate cells and marrow-derived mesenchymal stem cells.

Lin N, Tang Z, Deng M, Zhong Y, Lin J, Yang X, Xiang P, Xu R.

Biochem Biophys Res Commun. 2008 Jul 18;372(1):260-5. doi: 10.1016/j.bbrc.2008.05.029. Epub 2008 May 16.


The sonic hedgehog pathway mediates brain plasticity and subsequent functional recovery after bone marrow stromal cell treatment of stroke in mice.

Ding X, Li Y, Liu Z, Zhang J, Cui Y, Chen X, Chopp M.

J Cereb Blood Flow Metab. 2013 Jul;33(7):1015-24. doi: 10.1038/jcbfm.2013.50. Epub 2013 Apr 3.


Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway.

Ertao Z, Jianhui C, Chuangqi C, Changjiang Q, Sile C, Yulong H, Hui W, Shirong C.

J Exp Clin Cancer Res. 2016 Apr 2;35:63. doi: 10.1186/s13046-016-0336-9.


De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis.

El-Zaatari M, Tobias A, Grabowska AM, Kumari R, Scotting PJ, Kaye P, Atherton J, Clarke PA, Powe DG, Watson SA.

Br J Cancer. 2007 Jun 18;96(12):1855-61. Epub 2007 May 15.


Sonic hedgehog and CDX2 expression in the stomach.

Shiotani A, Kamada T, Yamanaka Y, Manabe N, Kusunoki H, Hata J, Haruma K.

J Gastroenterol Hepatol. 2008 Dec;23 Suppl 2:S161-6. doi: 10.1111/j.1440-1746.2008.05406.x. Review.


Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer.

Song Z, Yue W, Wei B, Wang N, Li T, Guan L, Shi S, Zeng Q, Pei X, Chen L.

PLoS One. 2011 Mar 4;6(3):e17687. doi: 10.1371/journal.pone.0017687.


Direct repression of Sonic Hedgehog expression in the stomach by Cdx2 leads to intestinal transformation.

Mutoh H, Hayakawa H, Sashikawa M, Sakamoto H, Sugano K.

Biochem J. 2010 Apr 14;427(3):423-34. doi: 10.1042/BJ20091177.


The role of Sonic Hedgehog as a regulator of gastric function and differentiation.

Feng R, Xiao C, Zavros Y.

Vitam Horm. 2012;88:473-489. doi: 10.1016/B978-0-12-394622-5.00021-3. Review.


Bone marrow-derived mesenchymal stem cells favor the immunosuppressive T cells skewing in a Helicobacter pylori model of gastric cancer.

Lin R, Ma H, Ding Z, Shi W, Qian W, Song J, Hou X.

Stem Cells Dev. 2013 Nov 1;22(21):2836-48. doi: 10.1089/scd.2013.0166. Epub 2013 Aug 16.


Sonic hedgehog protein promotes proliferation and chondrogenic differentiation of bone marrow-derived mesenchymal stem cells in vitro.

Warzecha J, Göttig S, Brüning C, Lindhorst E, Arabmothlagh M, Kurth A.

J Orthop Sci. 2006 Oct;11(5):491-6.


Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells.

Xiao C, Ogle SA, Schumacher MA, Orr-Asman MA, Miller ML, Lertkowit N, Varro A, Hollande F, Zavros Y.

Gastroenterology. 2010 Feb;138(2):550-61, 561.e1-8. doi: 10.1053/j.gastro.2009.11.002. Epub 2009 Nov 10.


Therapeutic potential of genetically modified mesenchymal stem cells after neonatal hypoxic-ischemic brain damage.

van Velthoven CT, Braccioli L, Willemen HL, Kavelaars A, Heijnen CJ.

Mol Ther. 2014 Mar;22(3):645-654. doi: 10.1038/mt.2013.260. Epub 2013 Oct 31.

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