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Items: 1 to 20 of 95

1.

Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice.

Nagahara AH, Mateling M, Kovacs I, Wang L, Eggert S, Rockenstein E, Koo EH, Masliah E, Tuszynski MH.

J Neurosci. 2013 Sep 25;33(39):15596-602. doi: 10.1523/JNEUROSCI.5195-12.2013.

2.

Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.

Peng S, Garzon DJ, Marchese M, Klein W, Ginsberg SD, Francis BM, Mount HT, Mufson EJ, Salehi A, Fahnestock M.

J Neurosci. 2009 Jul 22;29(29):9321-9. doi: 10.1523/JNEUROSCI.4736-08.2009.

3.

Conditional Depletion of Hippocampal Brain-Derived Neurotrophic Factor Exacerbates Neuropathology in a Mouse Model of Alzheimer's Disease.

Braun DJ, Kalinin S, Feinstein DL.

ASN Neuro. 2017 Mar-Apr;9(2):1759091417696161. doi: 10.1177/1759091417696161.

4.

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease.

Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JM, Rockenstein E, Chao MV, Koo EH, Geschwind D, Masliah E, Chiba AA, Tuszynski MH.

Nat Med. 2009 Mar;15(3):331-7. doi: 10.1038/nm.1912. Epub 2009 Feb 8.

5.

In vitro validation of effects of BDNF-expressing mesenchymal stem cells on neurodegeneration in primary cultured neurons of APP/PS1 mice.

Song MS, Learman CR, Ahn KC, Baker GB, Kippe J, Field EM, Dunbar GL.

Neuroscience. 2015 Oct 29;307:37-50. doi: 10.1016/j.neuroscience.2015.08.011. Epub 2015 Aug 20.

PMID:
26297896
6.

The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease.

Rantamäki T, Kemppainen S, Autio H, Stavén S, Koivisto H, Kojima M, Antila H, Miettinen PO, Kärkkäinen E, Karpova N, Vesa L, Lindemann L, Hoener MC, Tanila H, Castrén E.

PLoS One. 2013 Jul 3;8(7):e68722. doi: 10.1371/journal.pone.0068722. Print 2013.

7.

CHF5074, a novel gamma-secretase modulator, restores hippocampal neurogenesis potential and reverses contextual memory deficit in a transgenic mouse model of Alzheimer's disease.

Imbimbo BP, Giardino L, Sivilia S, Giuliani A, Gusciglio M, Pietrini V, Del Giudice E, D'Arrigo A, Leon A, Villetti G, Calzà L.

J Alzheimers Dis. 2010;20(1):159-73. doi: 10.3233/JAD-2010-1366.

PMID:
20164581
8.

Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network.

Harris JA, Devidze N, Verret L, Ho K, Halabisky B, Thwin MT, Kim D, Hamto P, Lo I, Yu GQ, Palop JJ, Masliah E, Mucke L.

Neuron. 2010 Nov 4;68(3):428-41. doi: 10.1016/j.neuron.2010.10.020.

9.
10.

Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease.

Chin J, Massaro CM, Palop JJ, Thwin MT, Yu GQ, Bien-Ly N, Bender A, Mucke L.

J Neurosci. 2007 Mar 14;27(11):2727-33.

11.

Age-related changes of neuron numbers in the frontal cortex of a transgenic mouse model of Alzheimer's disease.

Lemmens MA, Sierksma AS, Rutten BP, Dennissen F, Steinbusch HW, Lucassen PJ, Schmitz C.

Brain Struct Funct. 2011 Sep;216(3):227-37. doi: 10.1007/s00429-011-0305-1. Epub 2011 Mar 16.

12.

Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss.

Takeuchi A, Irizarry MC, Duff K, Saido TC, Hsiao Ashe K, Hasegawa M, Mann DM, Hyman BT, Iwatsubo T.

Am J Pathol. 2000 Jul;157(1):331-9. Erratum in: Am J Pathol 2000 Oct;157(4):1413.

13.

Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice.

Lin TW, Shih YH, Chen SJ, Lien CH, Chang CY, Huang TY, Chen SH, Jen CJ, Kuo YM.

Neurobiol Learn Mem. 2015 Feb;118:189-97. doi: 10.1016/j.nlm.2014.12.005. Epub 2014 Dec 24.

PMID:
25543023
14.

Neuroprotective role of MMP-9 overexpression in the brain of Alzheimer's 5xFAD mice.

Fragkouli A, Tsilibary EC, Tzinia AK.

Neurobiol Dis. 2014 Oct;70:179-89. doi: 10.1016/j.nbd.2014.06.021. Epub 2014 Jul 6.

PMID:
25008761
15.

Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice.

DaRocha-Souto B, Scotton TC, Coma M, Serrano-Pozo A, Hashimoto T, Serenó L, Rodríguez M, Sánchez B, Hyman BT, Gómez-Isla T.

J Neuropathol Exp Neurol. 2011 May;70(5):360-76. doi: 10.1097/NEN.0b013e318217a118.

16.

The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice.

Li N, Liu GT.

Acta Pharmacol Sin. 2010 Mar;31(3):265-72. doi: 10.1038/aps.2010.3. Epub 2010 Feb 15.

17.

Induction of brain-derived neurotrophic factor in plaque-associated glial cells of aged APP23 transgenic mice.

Burbach GJ, Hellweg R, Haas CA, Del Turco D, Deicke U, Abramowski D, Jucker M, Staufenbiel M, Deller T.

J Neurosci. 2004 Mar 10;24(10):2421-30.

18.

Social interaction rescues memory deficit in an animal model of Alzheimer's disease by increasing BDNF-dependent hippocampal neurogenesis.

Hsiao YH, Hung HC, Chen SH, Gean PW.

J Neurosci. 2014 Dec 3;34(49):16207-19. doi: 10.1523/JNEUROSCI.0747-14.2014.

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