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Items: 1 to 20 of 115

1.

Genotype-dependent effects of TGF-β1 on mast cell function: targeting the Stat5 pathway.

Fernando J, Faber TW, Pullen NA, Falanga YT, Kolawole EM, Oskeritzian CA, Barnstein BO, Bandara G, Li G, Schwartz LB, Spiegel S, Straus DB, Conrad DH, Bunting KD, Ryan JJ.

J Immunol. 2013 Nov 1;191(9):4505-13. doi: 10.4049/jimmunol.1202723.

2.

The Transcription Factor Ehf Is Involved in TGF-β-Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells.

Yamazaki S, Nakano N, Honjo A, Hara M, Maeda K, Nishiyama C, Kitaura J, Ohtsuka Y, Okumura K, Ogawa H, Shimizu T.

J Immunol. 2015 Oct 1;195(7):3427-35. doi: 10.4049/jimmunol.1402856.

3.

Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production.

Pullen NA, Barnstein BO, Falanga YT, Wang Z, Suzuki R, Tamang TD, Khurana MC, Harry EA, Draber P, Bunting KD, Mizuno K, Wilson BS, Ryan JJ.

J Biol Chem. 2012 Jan 13;287(3):2045-54. doi: 10.1074/jbc.M111.311142.

4.

TGF-beta 1 inhibits mast cell Fc epsilon RI expression.

Gomez G, Ramirez CD, Rivera J, Patel M, Norozian F, Wright HV, Kashyap MV, Barnstein BO, Fischer-Stenger K, Schwartz LB, Kepley CL, Ryan JJ.

J Immunol. 2005 May 15;174(10):5987-93.

5.

PTPalpha activates Lyn and Fyn and suppresses Hck to negatively regulate FcepsilonRI-dependent mast cell activation and allergic responses.

Samayawardhena LA, Pallen CJ.

J Immunol. 2010 Nov 15;185(10):5993-6002. doi: 10.4049/jimmunol.1001261.

6.

Cutting edge: CD4 T cell-mast cell interactions alter IgE receptor expression and signaling.

Kashyap M, Thornton AM, Norton SK, Barnstein B, Macey M, Brenzovich J, Shevach E, Leonard WJ, Ryan JJ.

J Immunol. 2008 Feb 15;180(4):2039-43.

7.
8.

Saucerneol F inhibits tumor necrosis factor-α and IL-6 production by suppressing Fyn-mediated pathways in FcεRI-mediated mast cells.

Lu Y, Piao D, Zhang H, Li X, Chao GH, Park SJ, Chang YC, Kim CH, Murakami M, Jung SH, Choi JH, Son JK, Chang HW.

Food Chem Toxicol. 2013 Sep;59:696-702. doi: 10.1016/j.fct.2013.06.056.

PMID:
23851146
9.

IL-10 suppresses mast cell IgE receptor expression and signaling in vitro and in vivo.

Kennedy Norton S, Barnstein B, Brenzovich J, Bailey DP, Kashyap M, Speiran K, Ford J, Conrad D, Watowich S, Moralle MR, Kepley CL, Murray PJ, Ryan JJ.

J Immunol. 2008 Mar 1;180(5):2848-54.

10.

Autocrine hemokinin-1 functions as an endogenous adjuvant for IgE-mediated mast cell inflammatory responses.

Sumpter TL, Ho CH, Pleet AR, Tkacheva OA, Shufesky WJ, Rojas-Canales DM, Morelli AE, Larregina AT.

J Allergy Clin Immunol. 2015 Apr;135(4):1019-30.e8. doi: 10.1016/j.jaci.2014.07.036.

11.

Stat5 expression is required for IgE-mediated mast cell function.

Barnstein BO, Li G, Wang Z, Kennedy S, Chalfant C, Nakajima H, Bunting KD, Ryan JJ.

J Immunol. 2006 Sep 1;177(5):3421-6.

12.

FcepsilonRI-alpha siRNA inhibits the antigen-induced activation of mast cells.

Safaralizadeh R, Soheili ZS, Deezagi A, Pourpak Z, Samiei S, Moin M.

Iran J Allergy Asthma Immunol. 2009 Dec;8(4):177-83. doi: 08.04/ijaai.177183.

13.

The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells.

Barbu EA, Zhang J, Siraganian RP.

J Biol Chem. 2010 May 21;285(21):15761-8. doi: 10.1074/jbc.M110.109413.

14.

IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis.

Macey MR, Sturgill JL, Morales JK, Falanga YT, Morales J, Norton SK, Yerram N, Shim H, Fernando J, Gifillan AM, Gomez G, Schwartz L, Oskeritzian C, Spiegel S, Conrad D, Ryan JJ.

J Immunol. 2010 May 1;184(9):4688-95. doi: 10.4049/jimmunol.0903477.

15.
16.

TGF-beta1 inhibits late-stage mast cell maturation.

Kashyap M, Bailey DP, Gomez G, Rivera J, Huff TF, Ryan JJ.

Exp Hematol. 2005 Nov;33(11):1281-91.

PMID:
16263412
17.

The Src family kinase Fgr is critical for activation of mast cells and IgE-mediated anaphylaxis in mice.

Lee JH, Kim JW, Kim DK, Kim HS, Park HJ, Park DK, Kim AR, Kim B, Beaven MA, Park KL, Kim YM, Choi WS.

J Immunol. 2011 Aug 15;187(4):1807-15. doi: 10.4049/jimmunol.1100296.

18.

Human mast cell line-1 (HMC-1) cells transfected with FcεRIα are sensitive to IgE/antigen-mediated stimulation demonstrating selectivity towards cytokine production.

Xia YC, Sun S, Kuek LE, Lopata AL, Hulett MD, Mackay GA.

Int Immunopharmacol. 2011 Aug;11(8):1002-11. doi: 10.1016/j.intimp.2011.02.017.

PMID:
21356342
19.

Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses.

Akimoto M, Mishra K, Lim KT, Tani N, Hisanaga SI, Katagiri T, Elson A, Mizuno K, Yakura H.

Scand J Immunol. 2009 May;69(5):401-11. doi: 10.1111/j.1365-3083.2009.02235.x.

20.

The role of Src family kinases in mast cell effector function.

Furumoto Y, Gomez G, Gonzalez-Espinosa C, Kovarova M, Odom S, Ryan JJ, Rivera J.

Novartis Found Symp. 2005;271:39-47; discussion 47-53, 95-9. Review.

PMID:
16605127

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