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Items: 1 to 20 of 98

1.

miR128 up-regulation correlates with impaired amyloid β(1-42) degradation in monocytes from patients with sporadic Alzheimer's disease.

Tiribuzi R, Crispoltoni L, Porcellati S, Di Lullo M, Florenzano F, Pirro M, Bagaglia F, Kawarai T, Zampolini M, Orlacchio A, Orlacchio A.

Neurobiol Aging. 2014 Feb;35(2):345-56. doi: 10.1016/j.neurobiolaging.2013.08.003. Epub 2013 Sep 21.

PMID:
24064186
2.

Decreased expression of cathepsin D in monocytes is related to the defective degradation of amyloid-β in Alzheimer's disease.

Tian L, Zhang K, Tian ZY, Wang T, Shang DS, Li B, Liu DX, Fang WG, Wang ZY, Chen YH.

J Alzheimers Dis. 2014;42(2):511-20. doi: 10.3233/JAD-132192.

PMID:
24898658
3.

Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients.

Tiribuzi R, Crispoltoni L, Chiurchiù V, Casella A, Montecchiani C, Del Pino AM, Maccarrone M, Palmerini CA, Caltagirone C, Kawarai T, Orlacchio A, Orlacchio A.

J Neurol Sci. 2017 Jan 15;372:408-412. doi: 10.1016/j.jns.2016.11.004. Epub 2016 Nov 6.

PMID:
27865556
4.

Alzheimer's disease.

De-Paula VJ, Radanovic M, Diniz BS, Forlenza OV.

Subcell Biochem. 2012;65:329-52. doi: 10.1007/978-94-007-5416-4_14. Review.

PMID:
23225010
5.

Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease.

Hook V, Funkelstein L, Wegrzyn J, Bark S, Kindy M, Hook G.

Biochim Biophys Acta. 2012 Jan;1824(1):89-104. doi: 10.1016/j.bbapap.2011.08.015. Epub 2011 Sep 8. Review.

6.

Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis.

Xiao Q, Yan P, Ma X, Liu H, Perez R, Zhu A, Gonzales E, Burchett JM, Schuler DR, Cirrito JR, Diwan A, Lee JM.

J Neurosci. 2014 Jul 16;34(29):9607-20. doi: 10.1523/JNEUROSCI.3788-13.2014.

7.

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease.

Lue LF, Kuo YM, Roher AE, Brachova L, Shen Y, Sue L, Beach T, Kurth JH, Rydel RE, Rogers J.

Am J Pathol. 1999 Sep;155(3):853-62.

8.

Clearance of cerebral Aβ in Alzheimer's disease: reassessing the role of microglia and monocytes.

Zuroff L, Daley D, Black KL, Koronyo-Hamaoui M.

Cell Mol Life Sci. 2017 Jun;74(12):2167-2201. doi: 10.1007/s00018-017-2463-7. Epub 2017 Feb 14. Review.

9.

Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes.

Möhle L, Israel N, Paarmann K, Krohn M, Pietkiewicz S, Müller A, Lavrik IN, Buguliskis JS, Schott BH, Schlüter D, Gundelfinger ED, Montag D, Seifert U, Pahnke J, Dunay IR.

Acta Neuropathol Commun. 2016 Mar 16;4:25. doi: 10.1186/s40478-016-0293-8.

10.

Regulation of Alzheimer beta-amyloid precursor trafficking and metabolism.

Gandy S, Petanceska S.

Biochim Biophys Acta. 2000 Jul 26;1502(1):44-52. Review.

11.

TFEB Participates in the Aβ-Induced Pathogenesis of Alzheimer's Disease by Regulating the Autophagy-Lysosome Pathway.

Zhang YD, Zhao JJ.

DNA Cell Biol. 2015 Nov;34(11):661-8. doi: 10.1089/dna.2014.2738. Epub 2015 Sep 14.

PMID:
26368054
12.

Effects of vitamin C on fibroblasts from sporadic Alzheimer's disease patients.

Costanzi E, Martino S, Persichetti E, Tiribuzi R, Massini C, Bernardi G, Orlacchio A, Orlacchio A.

Neurochem Res. 2008 Dec;33(12):2510-5. Epub 2007 Nov 28.

PMID:
18046644
13.

Lysosomal β-galactosidase and β-hexosaminidase activities correlate with clinical stages of dementia associated with Alzheimer's disease and type 2 diabetes mellitus.

Tiribuzi R, Orlacchio A, Crispoltoni L, Maiotti M, Zampolini M, De Angeliz M, Mecocci P, Cecchetti R, Bernardi G, Datti A, Martino S, Orlacchio A.

J Alzheimers Dis. 2011;24(4):785-97. doi: 10.3233/JAD-2011-100525.

PMID:
21321400
14.

Downregulated miR-29c correlates with increased BACE1 expression in sporadic Alzheimer's disease.

Lei X, Lei L, Zhang Z, Zhang Z, Cheng Y.

Int J Clin Exp Pathol. 2015 Feb 1;8(2):1565-74. eCollection 2015.

15.

Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models.

Reinert J, Richard BC, Klafki HW, Friedrich B, Bayer TA, Wiltfang J, Kovacs GG, Ingelsson M, Lannfelt L, Paetau A, Bergquist J, Wirths O.

Acta Neuropathol Commun. 2016 Mar 8;4:24. doi: 10.1186/s40478-016-0294-7.

16.

Intravenous infusion of monocytes isolated from 2-week-old mice enhances clearance of Beta-amyloid plaques in an Alzheimer mouse model.

Hohsfield LA, Humpel C.

PLoS One. 2015 Apr 1;10(4):e0121930. doi: 10.1371/journal.pone.0121930. eCollection 2015.

17.

Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis.

Xiao Q, Yan P, Ma X, Liu H, Perez R, Zhu A, Gonzales E, Tripoli DL, Czerniewski L, Ballabio A, Cirrito JR, Diwan A, Lee JM.

J Neurosci. 2015 Sep 2;35(35):12137-51. doi: 10.1523/JNEUROSCI.0705-15.2015.

18.

Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer's disease.

Xiang Y, Bu XL, Liu YH, Zhu C, Shen LL, Jiao SS, Zhu XY, Giunta B, Tan J, Song WH, Zhou HD, Zhou XF, Wang YJ.

Acta Neuropathol. 2015 Oct;130(4):487-99. doi: 10.1007/s00401-015-1477-1. Epub 2015 Sep 12.

19.

Methods to monitor monocytes-mediated amyloid-beta uptake and phagocytosis in the context of adjuvanted immunotherapies.

Hallé M, Tribout-Jover P, Lanteigne AM, Boulais J, St-Jean JR, Jodoin R, Girouard MP, Constantin F, Migneault A, Renaud F, Didierlaurent AM, Mallett CP, Burkhart D, Pilorget A, Palmantier R, Larocque D.

J Immunol Methods. 2015 Sep;424:64-79. doi: 10.1016/j.jim.2015.05.002. Epub 2015 May 19.

20.

Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases.

Wirths O, Bethge T, Marcello A, Harmeier A, Jawhar S, Lucassen PJ, Multhaup G, Brody DL, Esparza T, Ingelsson M, Kalimo H, Lannfelt L, Bayer TA.

J Neural Transm (Vienna). 2010 Jan;117(1):85-96. doi: 10.1007/s00702-009-0314-x. Epub 2009 Oct 13.

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