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Items: 1 to 20 of 142

1.

Efficacy of the prothrombin complex concentrate prothromplex in patients requiring urgent reversal of vitamin K antagonists or presenting with uncontrolled bleeding: a retrospective, single center study.

Leal-Noval SR, López-Irizo R, Bautista-Paloma J, Casado M, Arellano-Orden V, Leal-Romero M, Fernández-Hinojosa E, Puppo-Moreno A, Muñoz M.

Blood Coagul Fibrinolysis. 2013 Dec;24(8):862-8. doi: 10.1097/MBC.0b013e3283650cf9.

PMID:
24060736
2.

Prothrombin complex concentrate in surgical patients: retrospective evaluation of vitamin K antagonist reversal and treatment of severe bleeding.

Schick KS, Fertmann JM, Jauch KW, Hoffmann JN.

Crit Care. 2009;13(6):R191. doi: 10.1186/cc8186. Epub 2009 Nov 30.

3.

Reversal of Vitamin K Antagonist (VKA) effect in patients with severe bleeding: a French multicenter observational study (Optiplex) assessing the use of Prothrombin Complex Concentrate (PCC) in current clinical practice.

Desmettre T, Dehours E, Samama CM, Jhundoo S, Pujeau F, Guillaudin C, Hecquart C, Clerson P, Crave JC, Jaussaud R.

Crit Care. 2012 Oct 4;16(5):R185. doi: 10.1186/cc11669.

4.

Mortality in vitamin K antagonist-related intracerebral bleeding treated with plasma or 4-factor prothrombin complex concentrate.

Majeed A, Meijer K, Larrazabal R, Arnberg F, Luijckx GJ, Roberts RS, Schulman S.

Thromb Haemost. 2014 Feb;111(2):233-9. doi: 10.1160/TH13-07-0536. Epub 2013 Oct 24.

PMID:
24154891
5.

Efficacy and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists presenting with major bleeding: a randomized, plasma-controlled, phase IIIb study.

Sarode R, Milling TJ Jr, Refaai MA, Mangione A, Schneider A, Durn BL, Goldstein JN.

Circulation. 2013 Sep 10;128(11):1234-43. doi: 10.1161/CIRCULATIONAHA.113.002283. Epub 2013 Aug 9.

6.

Emergency reversal of anticoagulation with a three-factor prothrombin complex concentrate in patients with intracranial haemorrhage.

Imberti D, Barillari G, Biasioli C, Bianchi M, Contino L, Duce R, D'Incà M, Gnani MC, Mari E, Ageno W.

Blood Transfus. 2011 Apr;9(2):148-55. doi: 10.2450/2011.0065-10. Epub 2011 Jan 13.

7.

An international, multicenter, prospective study of a prothrombin complex concentrate, Prothromplex Total®, in anticoagulant reversal.

Altorjay Á, Szabó É, Boda Z, Kramer L, Ngo LY, Engl W, Firth CL, Ahlstrom ER, Gelmont DM, Pabinger I.

Thromb Res. 2015 Mar;135(3):485-91. doi: 10.1016/j.thromres.2014.12.026. Epub 2015 Jan 2.

PMID:
25613927
8.

Fixed versus variable dose of prothrombin complex concentrate for counteracting vitamin K antagonist therapy.

Khorsand N, Veeger NJ, Muller M, Overdiek JW, Huisman W, van Hest RM, Meijer K.

Transfus Med. 2011 Apr;21(2):116-23. doi: 10.1111/j.1365-3148.2010.01050.x. Epub 2010 Nov 15.

PMID:
21073580
9.

Prothrombin complex concentrates to reverse warfarin-induced coagulopathy in patients with intracranial bleeding.

Cabral KP, Fraser GL, Duprey J, Gibbons BA, Hayes T, Florman JE, Seder DB.

Clin Neurol Neurosurg. 2013 Jun;115(6):770-4. doi: 10.1016/j.clineuro.2012.07.006. Epub 2012 Jul 24.

PMID:
22835715
10.

Reversal of coagulopathy using prothrombin complex concentrates is associated with improved outcome compared to fresh frozen plasma in warfarin-associated intracranial hemorrhage.

Frontera JA, Gordon E, Zach V, Jovine M, Uchino K, Hussain MS, Aledort L.

Neurocrit Care. 2014 Dec;21(3):397-406. doi: 10.1007/s12028-014-9972-0.

PMID:
24671832
11.

Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial.

Goldstein JN, Refaai MA, Milling TJ Jr, Lewis B, Goldberg-Alberts R, Hug BA, Sarode R.

Lancet. 2015 May 23;385(9982):2077-87. doi: 10.1016/S0140-6736(14)61685-8. Epub 2015 Feb 27.

PMID:
25728933
12.

Prothrombin complex concentrate (Octaplex) in patients requiring immediate reversal of oral anticoagulation.

Riess HB, Meier-Hellmann A, Motsch J, Elias M, Kursten FW, Dempfle CE.

Thromb Res. 2007;121(1):9-16. Epub 2007 Apr 3.

PMID:
17407788
13.

PROTHROMBINEX(®)-VF (PTX-VF) usage for reversal of coagulopathy: prospective evaluation of thrombogenic risk.

Bobbitt L, Merriman E, Raynes J, Henderson R, Blacklock H, Chunilal S.

Thromb Res. 2011 Dec;128(6):577-82. doi: 10.1016/j.thromres.2011.04.017. Epub 2011 May 28.

PMID:
21621251
14.

Optimal dose of prothrombin complex concentrate for acute reversal of oral anticoagulation.

Yasaka M, Sakata T, Naritomi H, Minematsu K.

Thromb Res. 2005;115(6):455-9.

PMID:
15792675
15.

The use of vitamin K in patients on anticoagulant therapy: a practical guide.

Hanslik T, Prinseau J.

Am J Cardiovasc Drugs. 2004;4(1):43-55. Review.

PMID:
14967065
16.

A French multicenter randomised trial comparing two dose-regimens of prothrombin complex concentrates in urgent anticoagulation reversal.

Kerebel D, Joly LM, Honnart D, Schmidt J, Galanaud D, Negrier C, Kursten F, Coriat P; Lex206 Investigator Group..

Crit Care. 2013 Jan 10;17(1):R4. doi: 10.1186/cc11923.

17.

Dosing of 3-factor prothrombin complex concentrate for international normalized ratio reversal.

Baggs JH, Patanwala AE, Williams EM, Erstad BL.

Ann Pharmacother. 2012 Jan;46(1):51-6. doi: 10.1345/aph.1Q588. Epub 2011 Dec 20.

PMID:
22190253
18.

Evaluation of Warfarin Reversal with 4-Factor Prothrombin Complex Concentrate Compared to 3-Factor Prothrombin Complex Concentrate at a Tertiary Academic Medical Center.

Al-Majzoub O, Rybak E, Reardon DP, Krause P, Connors JM.

J Emerg Med. 2016 Jan;50(1):7-13. doi: 10.1016/j.jemermed.2015.07.024.

PMID:
26433428
19.

Emergency reversal of anticoagulation with vitamin K antagonists with 3-factor prothrombin complex concentrates in patients with major bleeding.

Imberti D, Magnacavallo A, Dentali F, Condoleo E, Gallerani M, Benedetti R, Ageno W.

J Thromb Thrombolysis. 2013 Jul;36(1):102-8. doi: 10.1007/s11239-012-0817-4.

PMID:
23054464
20.

Real world usage of PCC to "rapidly" correct warfarin induced coagulopathy.

Toth P, van Veen JJ, Robinson K, Maclean RM, Hampton KK, Laidlaw S, Makris M.

Blood Transfus. 2013 Oct;11(4):500-5. doi: 10.2450/2012.0113-12. Epub 2012 Oct 10.

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