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Items: 1 to 20 of 117

1.

I2-mediated oxidative C-O bond formation for the synthesis of 1,3,4-oxadiazoles from aldehydes and hydrazides.

Yu W, Huang G, Zhang Y, Liu H, Dong L, Yu X, Li Y, Chang J.

J Org Chem. 2013 Oct 18;78(20):10337-43. doi: 10.1021/jo401751h. Epub 2013 Oct 8.

PMID:
24059837
2.

Synthesis of 2-amino-1,3,4-oxadiazoles and 2-amino-1,3,4-thiadiazoles via sequential condensation and I2-mediated oxidative C–O/C–S bond formation.

Niu P, Kang J, Tian X, Song L, Liu H, Wu J, Yu W, Chang J.

J Org Chem. 2015 Jan 16;80(2):1018-24.

PMID:
25506709
3.

I2-Mediated Intramolecular C-H Amidation for the Synthesis of N-Substituted Benzimidazoles.

Hu Z, Zhao T, Wang M, Wu J, Yu W, Chang J.

J Org Chem. 2017 Mar 17;82(6):3152-3158. doi: 10.1021/acs.joc.7b00142. Epub 2017 Mar 2.

PMID:
28233495
4.

Synthesis of 1,2,4-Triazolo[4,3-a]pyridines and Related Heterocycles by Sequential Condensation and Iodine-Mediated Oxidative Cyclization.

Li E, Hu Z, Song L, Yu W, Chang J.

Chemistry. 2016 Jul 25;22(31):11022-7. doi: 10.1002/chem.201601744. Epub 2016 Jun 29.

PMID:
27355559
5.

Simple and efficient preparation of 2,5-disubstituted oxazoles via a metal-free-catalyzed cascade cyclization.

Wan C, Gao L, Wang Q, Zhang J, Wang Z.

Org Lett. 2010 Sep 3;12(17):3902-5. doi: 10.1021/ol101596s.

PMID:
20681600
6.

Direct Annulation of Hydrazides to 1,3,4-Oxadiazoles via Oxidative C(CO)-C(Methyl) Bond Cleavage of Methyl Ketones.

Gao Q, Liu S, Wu X, Zhang J, Wu A.

Org Lett. 2015 Jun 19;17(12):2960-3. doi: 10.1021/acs.orglett.5b01241. Epub 2015 Jun 2.

PMID:
26035338
7.

Synthesis of Quinazolines from N,N'-Disubstituted Amidines via I2/KI-Mediated Oxidative C-C Bond Formation.

Lv Z, Wang B, Hu Z, Zhou Y, Yu W, Chang J.

J Org Chem. 2016 Oct 21;81(20):9924-9930. Epub 2016 Oct 3.

PMID:
27676133
8.

I2-mediated oxidative C-N bond formation for metal-free one-pot synthesis of di-, tri-, and tetrasubstituted pyrazoles from α,β-unsaturated aldehydes/ketones and hydrazines.

Zhang X, Kang J, Niu P, Wu J, Yu W, Chang J.

J Org Chem. 2014 Nov 7;79(21):10170-8. doi: 10.1021/jo501844x. Epub 2014 Oct 16.

PMID:
25279429
9.

Iodine-Mediated Domino Oxidative Cyclization: One-Pot Synthesis of 1,3,4-Oxadiazoles via Oxidative Cleavage of C(sp(2))-H or C(sp)-H Bond.

Fan Y, He Y, Liu X, Hu T, Ma H, Yang X, Luo X, Huang G.

J Org Chem. 2016 Aug 5;81(15):6820-5. doi: 10.1021/acs.joc.6b01135. Epub 2016 Jul 21.

PMID:
27387390
10.

Hypervalent iodine(III) mediated synthesis of novel unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles as antibacterial and antifungal agents.

Prakash O, Kumar M, Kumar R, Sharma C, Aneja KR.

Eur J Med Chem. 2010 Sep;45(9):4252-7. doi: 10.1016/j.ejmech.2010.06.023. Epub 2010 Jun 22.

PMID:
20630627
11.

I2/TBPB mediated oxidative reaction of N-tosylhydrazones with anilines: practical construction of 1,4-disubstituted 1,2,3-triazoles under metal-free and azide-free conditions.

Cai ZJ, Lu XM, Zi Y, Yang C, Shen LJ, Li J, Wang SY, Ji SJ.

Org Lett. 2014 Oct 3;16(19):5108-11. doi: 10.1021/ol502431b. Epub 2014 Sep 24.

PMID:
25250817
12.

One-pot synthesis of 3,5-disubstituted 1,2,4-thiadiazoles from nitriles and thioamides via I2-mediated oxidative formation of an N-S bond.

Chai L, Xu Y, Ding T, Fang X, Zhang W, Wang Y, Lu M, Xu H, Yang X.

Org Biomol Chem. 2017 Oct 11;15(39):8410-8417. doi: 10.1039/c7ob01887h.

PMID:
28952634
13.

Synthesis of 5-Amino and 3,5-Diamino Substituted 1,2,4-Thiadiazoles by I2-Mediated Oxidative N-S Bond Formation.

Wang B, Meng Y, Zhou Y, Ren L, Wu J, Yu W, Chang J.

J Org Chem. 2017 Jun 2;82(11):5898-5903. doi: 10.1021/acs.joc.7b00814. Epub 2017 May 17.

PMID:
28494581
14.

I2-Catalyzed Oxidative N-S Bond Formation: Metal-Free Regiospecific Synthesis of N-Fused and 3,4-Disubstituted 5-Imino-1,2,4-thiadiazoles.

Tumula N, Jatangi N, Palakodety RK, Balasubramanian S, Nakka M.

J Org Chem. 2017 May 19;82(10):5310-5316. doi: 10.1021/acs.joc.7b00646. Epub 2017 May 4.

PMID:
28447462
15.

Synthesis of Novel Imidazo[1,2-a]pyridin-2-amines from Arylamines and Nitriles via Sequential Addition and I2 /KI-Mediated Oxidative Cyclization.

Tian X, Song L, Wang M, Lv Z, Wu J, Yu W, Chang J.

Chemistry. 2016 May 23;22(22):7617-22. doi: 10.1002/chem.201600849. Epub 2016 Apr 26.

PMID:
27112949
16.

Application of N-Acylbenzotriazoles in the Synthesis of 5-Substituted 2-Ethoxy-1,3,4-oxadiazoles as Building Blocks toward 3,5-Disubstituted 1,3,4-Oxadiazol-2(3H)-ones.

Wet-Osot S, Phakhodee W, Pattarawarapan M.

J Org Chem. 2017 Sep 15;82(18):9923-9929. doi: 10.1021/acs.joc.7b01863. Epub 2017 Sep 1.

PMID:
28862855
17.

Synthesis of 2-Aryl benzothiazoles via K2S2O8-mediated oxidative condensation of benzothiazoles with aryl aldehydes.

Yang Z, Chen X, Wang S, Liu J, Xie K, Wang A, Tan Z.

J Org Chem. 2012 Aug 17;77(16):7086-91. doi: 10.1021/jo300740j. Epub 2012 Aug 2.

PMID:
22835066
18.

From α-arylation of olefins to acylation with aldehydes: a journey in regiocontrol of the Heck reaction.

Ruan J, Xiao J.

Acc Chem Res. 2011 Aug 16;44(8):614-26. doi: 10.1021/ar200053d. Epub 2011 May 25. Review.

PMID:
21612205
19.

A convergent synthesis of 1,3,4-oxadiazoles from acyl hydrazides under semiaqueous conditions.

Tokumaru K, Johnston JN.

Chem Sci. 2017 Apr 1;8(4):3187-3191. doi: 10.1039/c7sc00195a. Epub 2017 Feb 23.

20.

An efficient synthesis and biological study of novel indolyl-1,3,4-oxadiazoles as potent anticancer agents.

Kumar D, Sundaree S, Johnson EO, Shah K.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4492-4. doi: 10.1016/j.bmcl.2009.03.172. Epub 2009 Jun 13.

PMID:
19559607

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