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Role of S-palmitoylation on IFITM5 for the interaction with FKBP11 in osteoblast cells.

Tsukamoto T, Li X, Morita H, Minowa T, Aizawa T, Hanagata N, Demura M.

PLoS One. 2013 Sep 18;8(9):e75831. doi: 10.1371/journal.pone.0075831. eCollection 2013.


Osteoblast-enriched membrane protein IFITM5 regulates the association of CD9 with an FKBP11-CD81-FPRP complex and stimulates expression of interferon-induced genes.

Hanagata N, Li X.

Biochem Biophys Res Commun. 2011 Jun 10;409(3):378-84. doi: 10.1016/j.bbrc.2011.04.136. Epub 2011 May 11.


Characterization of the osteoblast-specific transmembrane protein IFITM5 and analysis of IFITM5-deficient mice.

Hanagata N, Li X, Morita H, Takemura T, Li J, Minowa T.

J Bone Miner Metab. 2011 May;29(3):279-90. doi: 10.1007/s00774-010-0221-0. Epub 2010 Sep 14.


Natural antisense transcripts enhance bone formation by increasing sense IFITM5 transcription.

Liu Y, Liu H, Titus L, Boden SD.

Bone. 2012 Nov;51(5):933-8. doi: 10.1016/j.bone.2012.07.024. Epub 2012 Aug 2.


Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3.

Yount JS, Moltedo B, Yang YY, Charron G, Moran TM, López CB, Hang HC.

Nat Chem Biol. 2010 Aug;6(8):610-4. doi: 10.1038/nchembio.405. Epub 2010 Jul 4.


Topological mapping of BRIL reveals a type II orientation and effects of osteogenesis imperfecta mutations on its cellular destination.

Patoine A, Gaumond MH, Jaiswal PK, Fassier F, Rauch F, Moffatt P.

J Bone Miner Res. 2014 Sep;29(9):2004-16. doi: 10.1002/jbmr.2243.


S-palmitoylation and ubiquitination differentially regulate interferon-induced transmembrane protein 3 (IFITM3)-mediated resistance to influenza virus.

Yount JS, Karssemeijer RA, Hang HC.

J Biol Chem. 2012 Jun 1;287(23):19631-41. doi: 10.1074/jbc.M112.362095. Epub 2012 Apr 17.


Specificity of transmembrane protein palmitoylation in yeast.

González Montoro A, Chumpen Ramirez S, Quiroga R, Valdez Taubas J.

PLoS One. 2011 Feb 24;6(2):e16969. doi: 10.1371/journal.pone.0016969.


Distinct palmitoylation events at the amino-terminal conserved cysteines of Env7 direct its stability, localization, and vacuolar fusion regulation in S. cerevisiae.

Manandhar SP, Calle EN, Gharakhanian E.

J Biol Chem. 2014 Apr 18;289(16):11431-42. doi: 10.1074/jbc.M113.524082. Epub 2014 Mar 7.


IFITMs from Mycobacteria Confer Resistance to Influenza Virus When Expressed in Human Cells.

Melvin WJ, McMichael TM, Chesarino NM, Hach JC, Yount JS.

Viruses. 2015 Jun 12;7(6):3035-52. doi: 10.3390/v7062759.


The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry.

Narayana SK, Helbig KJ, McCartney EM, Eyre NS, Bull RA, Eltahla A, Lloyd AR, Beard MR.

J Biol Chem. 2015 Oct 23;290(43):25946-59. doi: 10.1074/jbc.M115.657346. Epub 2015 Sep 9.


Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex.

Fredericks GJ, Hoffmann FW, Rose AH, Osterheld HJ, Hess FM, Mercier F, Hoffmann PR.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16478-83. doi: 10.1073/pnas.1417176111. Epub 2014 Nov 3.


Palmitoylation of membrane proteins (Review).

Charollais J, Van Der Goot FG.

Mol Membr Biol. 2009 Jan;26(1):55-66. doi: 10.1080/09687680802620369. Epub 2008 Dec 10. Review.


Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation.

Foster JD, Vaughan RA.

J Biol Chem. 2011 Feb 18;286(7):5175-86. doi: 10.1074/jbc.M110.187872. Epub 2010 Nov 30.


The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity.

McMichael TM, Zhang L, Chemudupati M, Hach JC, Kenney AD, Hang HC, Yount JS.

J Biol Chem. 2017 Dec 29;292(52):21517-21526. doi: 10.1074/jbc.M117.800482. Epub 2017 Oct 27.


Differential functions of phospholipid binding and palmitoylation of tumour suppressor EWI2/PGRL.

He B, Zhang YH, Richardson MM, Zhang JS, Rubinstein E, Zhang XA.

Biochem J. 2011 Aug 1;437(3):399-411. doi: 10.1042/BJ20101381.


The inhibitory effect of phospholemman on the sodium pump requires its palmitoylation.

Tulloch LB, Howie J, Wypijewski KJ, Wilson CR, Bernard WG, Shattock MJ, Fuller W.

J Biol Chem. 2011 Oct 14;286(41):36020-31. doi: 10.1074/jbc.M111.282145. Epub 2011 Aug 25.


What does S-palmitoylation do to membrane proteins?

Blaskovic S, Blanc M, van der Goot FG.

FEBS J. 2013 Jun;280(12):2766-74. doi: 10.1111/febs.12263. Epub 2013 Apr 18. Review.

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