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Increased endoplasmic reticulum stress response is involved in clopidogrel-induced apoptosis of gastric epithelial cells.

Wu HL, Duan ZT, Jiang ZD, Cao WJ, Wang ZB, Hu KW, Gao X, Wang SK, He BS, Zhang ZY, Xie HG.

PLoS One. 2013 Sep 13;8(9):e74381. doi: 10.1371/journal.pone.0074381. eCollection 2013.


Attenuated expression of the tight junction proteins is involved in clopidogrel-induced gastric injury through p38 MAPK activation.

Wu HL, Gao X, Jiang ZD, Duan ZT, Wang SK, He BS, Zhang ZY, Xie HG.

Toxicology. 2013 Feb 8;304:41-8. doi: 10.1016/j.tox.2012.11.020. Epub 2012 Dec 7.


Helicobacter pylori and mitogen-activated protein kinases regulate the cell cycle, proliferation and apoptosis in gastric epithelial cells.

Ding SZ, Smith MF Jr, Goldberg JB.

J Gastroenterol Hepatol. 2008 Jul;23(7 Pt 2):e67-78. doi: 10.1111/j.1440-1746.2007.04912.x.


Sulforaphane enhances the ability of human retinal pigment epithelial cell against oxidative stress, and its effect on gene expression profile evaluated by microarray analysis.

Ye L, Yu T, Li Y, Chen B, Zhang J, Wen Z, Zhang B, Zhou X, Li X, Li F, Cao W, Huang Z.

Oxid Med Cell Longev. 2013;2013:413024. doi: 10.1155/2013/413024. Epub 2013 Sep 25.


[Effects of p38 mitogen-activated protein kinases on the apoptosis of human bronchial epithelial cells induced by refractory ceramic fibers in vitro].

Zhang M, Zhu LJ, Xiao Y, Zhang X.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2013 May;31(5):347-50. Chinese.


Genes and gene networks involved in sodium fluoride-elicited cell death accompanying endoplasmic reticulum stress in oral epithelial cells.

Tabuchi Y, Yunoki T, Hoshi N, Suzuki N, Kondo T.

Int J Mol Sci. 2014 May 20;15(5):8959-78. doi: 10.3390/ijms15058959.


Quantitative proteomic and transcriptional analysis of the response to the p38 mitogen-activated protein kinase inhibitor SB203580 in transformed follicular lymphoma cells.

Lin Z, Crockett DK, Jenson SD, Lim MS, Elenitoba-Johnson KS.

Mol Cell Proteomics. 2004 Aug;3(8):820-33. Epub 2004 May 28.


Sequential treatment of HPV E6 and E7-expressing TC-1 cells with bortezomib and celecoxib promotes apoptosis through p-p38 MAPK-mediated downregulation of cyclin D1 and CDK2.

Kim JE, Lee JI, Jin DH, Lee WJ, Park GB, Kim S, Kim YS, Wu TC, Hur DY, Kim D.

Oncol Rep. 2014 May;31(5):2429-37. doi: 10.3892/or.2014.3082. Epub 2014 Mar 12.


Clopidogrel delays gastric ulcer healing in rats.

Luo JC, Huo TI, Hou MC, Lin HY, Li CP, Lin HC, Chang FY, Lee FY.

Eur J Pharmacol. 2012 Nov 15;695(1-3):112-9. doi: 10.1016/j.ejphar.2012.07.054. Epub 2012 Sep 10.


HIV-1 gp120-induced tubular epithelial cell apoptosis is mediated through p38-MAPK phosphorylation.

Kapasi AA, Patel G, Franki N, Singhal PC.

Mol Med. 2002 Nov;8(11):676-85.


Differential regulation of ERK1/2 and p38 MAP kinases in VacA-induced apoptosis of gastric epithelial cells.

Ki MR, Lee HR, Goo MJ, Hong IH, Do SH, Jeong DH, Yang HJ, Yuan DW, Park JK, Jeong KS.

Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G635-47. Epub 2007 Dec 20.


Endoplasmic reticulum stress-induced hepatic stellate cell apoptosis through calcium-mediated JNK/P38 MAPK and Calpain/Caspase-12 pathways.

Huang Y, Li X, Wang Y, Wang H, Huang C, Li J.

Mol Cell Biochem. 2014 Sep;394(1-2):1-12. doi: 10.1007/s11010-014-2073-8. Epub 2014 Jun 25.


Aspirin induces gastric epithelial barrier dysfunction by activating p38 MAPK via claudin-7.

Oshima T, Miwa H, Joh T.

Am J Physiol Cell Physiol. 2008 Sep;295(3):C800-6. doi: 10.1152/ajpcell.00157.2008. Epub 2008 Jul 30.


Activation of p38 MAPK by reactive oxygen species is essential in a rat model of stress-induced gastric mucosal injury.

Jia YT, Wei W, Ma B, Xu Y, Liu WJ, Wang Y, Lv KY, Tang HT, Wei D, Xia ZF.

J Immunol. 2007 Dec 1;179(11):7808-19.


The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis.

Caba O, Rodríguez-Serrano F, Díaz-Gavilán M, Conejo-García A, Ortiz R, Martínez-Amat A, Alvarez P, Gallo MA, Campos JM, Marchal JA, Aránega A.

Eur J Med Chem. 2012 Apr;50:376-82. doi: 10.1016/j.ejmech.2012.02.017. Epub 2012 Feb 17.


Down-regulation of MSH2 expression by an Hsp90 inhibitor enhances pemetrexed-induced cytotoxicity in human non-small-cell lung cancer cells.

Tung CL, Chiu HC, Jian YJ, Jian YT, Chen CY, Syu JJ, Wo TY, Huang YJ, Tseng SC, Lin YW.

Exp Cell Res. 2014 Apr 1;322(2):345-54. doi: 10.1016/j.yexcr.2014.02.002. Epub 2014 Feb 12.


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