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Items: 1 to 20 of 142

1.

Calcineurin/NFAT pathway mediates wear particle-induced TNF-α release and osteoclastogenesis from mice bone marrow macrophages in vitro.

Liu FX, Wu CL, Zhu ZA, Li MQ, Mao YQ, Liu M, Wang XQ, Yu DG, Tang TT.

Acta Pharmacol Sin. 2013 Nov;34(11):1457-66. doi: 10.1038/aps.2013.99.

2.

Inhibition of titanium particle-induced osteoclastogenesis through inactivation of NFATc1 by VIVIT peptide.

Liu F, Zhu Z, Mao Y, Liu M, Tang T, Qiu S.

Biomaterials. 2009 Mar;30(9):1756-62. doi: 10.1016/j.biomaterials.2008.12.018.

PMID:
19118894
3.

NFAT2 is an essential mediator of orthopedic particle-induced osteoclastogenesis.

Yamanaka Y, Abu-Amer W, Foglia D, Otero J, Clohisy JC, Abu-Amer Y.

J Orthop Res. 2008 Dec;26(12):1577-84. doi: 10.1002/jor.20714.

4.

Molecular basis of requirement of receptor activator of nuclear factor κB signaling for interleukin 1-mediated osteoclastogenesis.

Jules J, Zhang P, Ashley JW, Wei S, Shi Z, Liu J, Michalek SM, Feng X.

J Biol Chem. 2012 May 4;287(19):15728-38. doi: 10.1074/jbc.M111.296228.

5.

Blockade of JNK and NFAT pathways attenuates orthopedic particle-stimulated osteoclastogenesis of human osteoclast precursors and murine calvarial osteolysis.

Yamanaka Y, Clohisy JC, Ito H, Matsuno T, Abu-Amer Y.

J Orthop Res. 2013 Jan;31(1):67-72. doi: 10.1002/jor.22200.

6.

Inhibitory effects of triptolide on titanium particle-induced osteolysis and receptor activator of nuclear factor-κB ligand-mediated osteoclast differentiation.

Kim JA, Ihn HJ, Park JY, Lim J, Hong JM, Kim SH, Kim SY, Shin HI, Park EK.

Int Orthop. 2015 Jan;39(1):173-82. doi: 10.1007/s00264-014-2596-3.

PMID:
25416122
7.

Arctigenin inhibits osteoclast differentiation and function by suppressing both calcineurin-dependent and osteoblastic cell-dependent NFATc1 pathways.

Yamashita T, Uehara S, Udagawa N, Li F, Kadota S, Esumi H, Kobayashi Y, Takahashi N.

PLoS One. 2014 Jan 17;9(1):e85878. doi: 10.1371/journal.pone.0085878.

8.

CTRP3 acts as a negative regulator of osteoclastogenesis through AMPK-c-Fos-NFATc1 signaling in vitro and RANKL-induced calvarial bone destruction in vivo.

Kim JY, Min JY, Baek JM, Ahn SJ, Jun HY, Yoon KH, Choi MK, Lee MS, Oh J.

Bone. 2015 Oct;79:242-51. doi: 10.1016/j.bone.2015.06.011.

PMID:
26103094
9.

Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-kappaB inhibitor, through downregulation of NFATc1.

Takatsuna H, Asagiri M, Kubota T, Oka K, Osada T, Sugiyama C, Saito H, Aoki K, Ohya K, Takayanagi H, Umezawa K.

J Bone Miner Res. 2005 Apr;20(4):653-62.

10.

TRAF2 is essential for TNF-alpha-induced osteoclastogenesis.

Kanazawa K, Kudo A.

J Bone Miner Res. 2005 May;20(5):840-7.

11.

Agelasine D suppresses RANKL-induced osteoclastogenesis via down-regulation of c-Fos, NFATc1 and NF-κB.

Kang MR, Jo SA, Yoon YD, Park KH, Oh SJ, Yun J, Lee CW, Nam KH, Kim Y, Han SB, Yu J, Rho J, Kang JS.

Mar Drugs. 2014 Nov 24;12(11):5643-56. doi: 10.3390/md12115643.

12.

BSP and RANKL induce osteoclastogenesis and bone resorption synergistically.

Valverde P, Tu Q, Chen J.

J Bone Miner Res. 2005 Sep;20(9):1669-79.

13.

Nuclear presence of nuclear factor of activated T cells (NFAT) c3 and c4 is required for Toll-like receptor-activated innate inflammatory response of monocytes/macrophages.

Minematsu H, Shin MJ, Celil Aydemir AB, Kim KO, Nizami SA, Chung GJ, Lee FY.

Cell Signal. 2011 Nov;23(11):1785-93. doi: 10.1016/j.cellsig.2011.06.013.

14.

FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans.

Yu H, Herbert BA, Valerio M, Yarborough L, Hsu LC, Argraves KM.

Lipids Health Dis. 2015 Jul 4;14:66. doi: 10.1186/s12944-015-0057-7.

15.

Zinc inhibits osteoclast differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway.

Park KH, Park B, Yoon DS, Kwon SH, Shin DM, Lee JW, Lee HG, Shim JH, Park JH, Lee JM.

Cell Commun Signal. 2013 Oct 2;11:74. doi: 10.1186/1478-811X-11-74.

16.

Geraniin suppresses RANKL-induced osteoclastogenesis in vitro and ameliorates wear particle-induced osteolysis in mouse model.

Xiao F, Zhai Z, Jiang C, Liu X, Li H, Qu X, Ouyang Z, Fan Q, Tang T, Qin A, Gu D.

Exp Cell Res. 2015 Jan 1;330(1):91-101. doi: 10.1016/j.yexcr.2014.07.005.

PMID:
25016282
17.

Angelica sinensis extract inhibits RANKL-mediated osteoclastogenesis by down-regulated the expression of NFATc1 in mouse bone marrow cells.

Kong L, Zhao Q, Wang X, Zhu J, Hao D, Yang C.

BMC Complement Altern Med. 2014 Dec 12;14:481. doi: 10.1186/1472-6882-14-481.

18.

Coptisine inhibits RANKL-induced NF-κB phosphorylation in osteoclast precursors and suppresses function through the regulation of RANKL and OPG gene expression in osteoblastic cells.

Lee JW, Iwahashi A, Hasegawa S, Yonezawa T, Jeon WB, Cha BY, Nagai K, Woo JT.

J Nat Med. 2012 Jan;66(1):8-16. doi: 10.1007/s11418-011-0537-7.

PMID:
21656335
19.

Inhibiting wear particles-induced osteolysis with doxycycline.

Zhang C, Tang TT, Ren WP, Zhang XL, Dai KR.

Acta Pharmacol Sin. 2007 Oct;28(10):1603-10.

20.

Adenovirus-mediated small interfering RNA targeting tumor necrosis factor-α inhibits titanium particle-induced osteoclastogenesis and bone resorption.

Guo H, Zhang J, Hao S, Jin Q.

Int J Mol Med. 2013 Aug;32(2):296-306. doi: 10.3892/ijmm.2013.1416.

PMID:
23760678

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