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Items: 1 to 20 of 91

1.

Mitochondrial mutations and ageing: can mitochondrial deletion mutants accumulate via a size based replication advantage?

Kowald A, Dawson M, Kirkwood TB.

J Theor Biol. 2014 Jan 7;340:111-8. doi: 10.1016/j.jtbi.2013.09.009. Epub 2013 Sep 17.

PMID:
24055401
2.
3.

Transcription could be the key to the selection advantage of mitochondrial deletion mutants in aging.

Kowald A, Kirkwood TB.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):2972-7. doi: 10.1073/pnas.1314970111. Epub 2014 Feb 3.

4.

Mitochondrial DNA alterations as ageing-associated molecular events.

Wei YH.

Mutat Res. 1992 Sep;275(3-6):145-55. Review.

PMID:
1383757
5.

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development.

Ross JM, Stewart JB, Hagström E, Brené S, Mourier A, Coppotelli G, Freyer C, Lagouge M, Hoffer BJ, Olson L, Larsson NG.

Nature. 2013 Sep 19;501(7467):412-5. doi: 10.1038/nature12474. Epub 2013 Aug 21.

6.

Is selection required for the accumulation of somatic mitochondrial DNA mutations in post-mitotic cells?

Durham SE, Samuels DC, Chinnery PF.

Neuromuscul Disord. 2006 Jun;16(6):381-6. Epub 2006 May 8.

PMID:
16684599
7.

Contribution of common deletion to total deletion burden in mitochondrial DNA from inner ear of d-galactose-induced aging rats.

Zhong Y, Hu YJ, Yang Y, Peng W, Sun Y, Chen B, Huang X, Kong WJ.

Mutat Res. 2011 Jul 1;712(1-2):11-9. doi: 10.1016/j.mrfmmm.2011.03.013. Epub 2011 Apr 5.

PMID:
21473872
8.

On the relevance of mitochondrial fusions for the accumulation of mitochondrial deletion mutants: a modelling study.

Kowald A, Jendrach M, Pohl S, Bereiter-Hahn J, Hammerstein P.

Aging Cell. 2005 Oct;4(5):273-83.

9.
10.

Mutations of mitochondrial DNA - cause or consequence of the ageing process?

Meissner C.

Z Gerontol Geriatr. 2007 Oct;40(5):325-33. Review.

PMID:
17943235
11.

Mitochondria and ageing.

Müller-Höcker J.

Brain Pathol. 1992 Apr;2(2):149-58. Review.

PMID:
1341956
12.

In vivo interaction between mitochondria carrying mtDNAs from different mouse species.

Sato A, Nakada K, Shitara H, Yonekawa H, Hayashi J.

Genetics. 2004 Aug;167(4):1855-61.

13.

Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing.

Greaves LC, Nooteboom M, Elson JL, Tuppen HA, Taylor GA, Commane DM, Arasaradnam RP, Khrapko K, Taylor RW, Kirkwood TB, Mathers JC, Turnbull DM.

PLoS Genet. 2014 Sep 18;10(9):e1004620. doi: 10.1371/journal.pgen.1004620. eCollection 2014 Sep.

14.

Longevity Is Linked to Mitochondrial Mutation Rates in Rockfish: A Test Using Poisson Regression.

Hua X, Cowman P, Warren D, Bromham L.

Mol Biol Evol. 2015 Oct;32(10):2633-45. doi: 10.1093/molbev/msv137. Epub 2015 Jun 5.

PMID:
26048547
15.

Mitochondrial DNA mutation and the ageing process: bioenergy and pharmacological intervention.

Linnane AW, Zhang C, Baumer A, Nagley P.

Mutat Res. 1992 Sep;275(3-6):195-208. Review.

PMID:
1383761
17.

Mitochondrial DNA mutations in disease and ageing.

Cottrell DA, Blakely EL, Johnson MA, Borthwick GM, Ince PI, Turnbull DM.

Novartis Found Symp. 2001;235:234-43; discussion 243-6. Review.

PMID:
11280028
18.

Mathematical modeling of the role of mitochondrial fusion and fission in mitochondrial DNA maintenance.

Tam ZY, Gruber J, Halliwell B, Gunawan R.

PLoS One. 2013 Oct 11;8(10):e76230. doi: 10.1371/journal.pone.0076230. eCollection 2013.

19.

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.

Vermulst M, Wanagat J, Kujoth GC, Bielas JH, Rabinovitch PS, Prolla TA, Loeb LA.

Nat Genet. 2008 Apr;40(4):392-4. doi: 10.1038/ng.95. Epub 2008 Mar 2.

PMID:
18311139
20.

Context-Dependent Role of Mitochondrial Fusion-Fission in Clonal Expansion of mtDNA Mutations.

Tam ZY, Gruber J, Halliwell B, Gunawan R.

PLoS Comput Biol. 2015 May 21;11(5):e1004183. doi: 10.1371/journal.pcbi.1004183. eCollection 2015 May.

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